sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 1.347 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 1.112 | |
| 3o26 | NDP | Salutaridine reductase | / | 1.006 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.981 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.952 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.855 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.846 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.840 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.836 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.836 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.833 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.833 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.830 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.828 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.825 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.824 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.823 | |
| 4kwh | NAP | Reductase homolog | / | 0.822 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.821 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.819 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.817 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.817 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.807 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.807 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.805 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.803 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.802 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.799 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.799 | |
| 1sny | NAP | LD36273p | / | 0.798 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.798 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.795 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.793 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.793 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.791 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.790 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.789 | |
| 4qec | NAP | ElxO | / | 0.789 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.788 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.788 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.786 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.786 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.786 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.785 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.785 | |
| 4u7w | NDP | MxaA | / | 0.785 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.784 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.783 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.783 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.783 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.780 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.779 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.779 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.778 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.777 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.777 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.776 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.774 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.773 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.771 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.771 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.770 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.770 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.768 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.767 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.766 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.765 | |
| 3uce | NDP | Dehydrogenase | / | 0.764 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.764 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.763 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.762 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.760 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.759 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.759 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.757 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.757 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.757 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.756 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.755 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.754 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.753 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.752 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.751 | |
| 1iy8 | NAD | Levodione reductase | / | 0.748 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.748 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.746 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.742 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.742 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.741 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.741 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.741 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.740 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.738 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.738 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.737 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.737 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.736 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.736 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.735 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.735 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.733 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.732 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.732 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.731 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.730 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.729 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.728 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.728 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.727 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.727 | |
| 4qed | NAP | ElxO | / | 0.727 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.726 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.726 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.725 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.724 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.723 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.722 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.722 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.722 | |
| 3bmo | NAP | Pteridine reductase | / | 0.721 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.720 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.720 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.720 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.719 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.719 | |
| 4hxy | NDP | Plm1 | / | 0.719 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.719 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.718 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.718 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.717 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.716 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.716 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.716 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.715 | |
| 4clo | NAP | Pteridine reductase | / | 0.715 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.714 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.714 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.714 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.712 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.711 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.710 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.710 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.709 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.709 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.709 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.709 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.709 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.709 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.709 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.708 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.708 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.708 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.706 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.706 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.705 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.704 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.704 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.704 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.704 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.703 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.702 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.702 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.701 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.701 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.700 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.700 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.697 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.697 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.697 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.696 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.694 | |
| 4ccq | NAP | Thioredoxin reductase | / | 0.694 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.694 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.693 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.691 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.690 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.690 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.690 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.689 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.689 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.688 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.687 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.686 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.684 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.684 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.683 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.683 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.682 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.681 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.679 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.679 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.679 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.678 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.678 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.677 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.677 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.677 | |
| 3mje | NDP | AmphB | / | 0.676 | |
| 1enp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.675 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.674 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.673 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.673 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.672 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.672 | |
| 3sju | NDP | Keto reductase | / | 0.671 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.670 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.670 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.669 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.669 | |
| 5cku | NAP | L-ornithine N(5)-monooxygenase | / | 0.669 | |
| 2bja | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.668 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.668 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.667 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.666 | |
| 5d2e | NAP | MlnE | / | 0.666 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.665 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.665 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.665 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.665 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.663 | |
| 2q0l | NAP | Thioredoxin reductase | 1.8.1.9 | 0.663 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.663 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.662 | |
| 2zzc | NAP | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.662 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.662 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.662 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.661 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.661 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.661 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.661 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.658 | |
| 2p9e | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.658 | |
| 1i36 | NAP | Conserved protein | / | 0.657 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.657 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.656 | |
| 4fda | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.655 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.654 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.654 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.653 | |
| 3qfs | NAP | NADPH--cytochrome P450 reductase | / | 0.653 | |
| 3qft | NAP | NADPH--cytochrome P450 reductase | / | 0.653 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.653 | |
| 3nt6 | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.652 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.652 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.652 | |
| 3lzx | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.651 | |
| 3qfc | NAP | NADPH--cytochrome P450 reductase | / | 0.651 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.650 |