sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1s14 | NOV | DNA topoisomerase 4 subunit B |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1s14 | NOV | DNA topoisomerase 4 subunit B | / | 1.000 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.485 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.479 | |
| 4hvg | 19Q | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.479 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.475 | |
| 3u2x | ASO | Glycogenin-1 | 2.4.1.186 | 0.474 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.471 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.468 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.468 | |
| 1aj8 | COA | Citrate synthase | / | 0.467 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.467 | |
| 1c2t | NHS | Phosphoribosylglycinamide formyltransferase | / | 0.466 | |
| 1njs | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.466 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.465 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.465 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.464 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.463 | |
| 3cr3 | ADP | PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.462 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.461 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.460 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.459 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 1rbq | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.459 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2ele | SAH | Diphthine synthase | / | 0.459 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.459 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.459 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.459 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.459 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.458 | |
| 3zsi | 52P | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.458 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.458 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.458 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2huv | SAH | Diphthine synthase | / | 0.457 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.457 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.457 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.456 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.456 | |
| 3nu3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.456 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.455 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.455 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2p6i | SAH | Diphthine synthase | / | 0.455 | |
| 2pck | SAH | Diphthine synthase | / | 0.455 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 1qvn | FRI | Interleukin-2 | / | 0.454 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.454 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.454 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.454 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.454 | |
| 3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3sqq | 99Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.454 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.454 | |
| 1sxj | ADP | Replication factor C subunit 5 | / | 0.453 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.453 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.453 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.453 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.453 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.452 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.452 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 1adc | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1c3e | NHR | Phosphoribosylglycinamide formyltransferase | / | 0.451 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1q0q | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.451 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.451 | |
| 2huq | SAH | Diphthine synthase | / | 0.451 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.451 | |
| 3ckt | YDP | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.451 | |
| 2owk | SAH | Diphthine synthase | / | 0.450 | |
| 3da1 | FAD | Glycerol-3-phosphate dehydrogenase | / | 0.450 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4ple | CPS | Nuclear receptor subfamily 5 group A member 2 | / | 0.450 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.449 | |
| 1xny | 191 | Propionyl-CoA carboxylase complex B subunit | / | 0.449 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2dwp | ACP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.449 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.449 | |
| 4an2 | EUI | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.449 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4k5p | 1OS | M1 family aminopeptidase | 3.4.11 | 0.449 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.449 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2e16 | SAH | Diphthine synthase | / | 0.448 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3c4x | ATP | Rhodopsin kinase | / | 0.448 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.448 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.448 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.448 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.447 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1z1r | HBH | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2e8r | SAH | Diphthine synthase | / | 0.447 | |
| 2i1v | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.447 | |
| 3mxd | K53 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3sls | 77D | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.447 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.447 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.447 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.447 | |
| 4pd6 | URI | Nucleoside permease | / | 0.447 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.446 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.446 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.446 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.446 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1g38 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.445 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.445 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.445 | |
| 3gep | 24H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.445 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.445 | |
| 4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.445 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.445 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.444 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.444 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.444 | |
| 2qd9 | LGF | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.444 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.444 | |
| 4nfh | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 4z9r | NAD | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.444 | |
| 1b3r | NAD | Adenosylhomocysteinase | 3.3.1.1 | 0.443 | |
| 1hvh | Q82 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.443 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.443 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.443 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.443 | |
| 2p9d | SAH | Diphthine synthase | / | 0.443 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.443 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.443 | |
| 3qa2 | XNA | Ketohexokinase | / | 0.443 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.443 | |
| 4hxy | NDP | Plm1 | / | 0.443 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.442 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.442 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.442 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.442 | |
| 1rc0 | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.442 | |
| 2b60 | RIT | Pol polyprotein | / | 0.442 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2i4u | DJR | Protease | / | 0.442 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.442 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.442 | |
| 2q6s | PLB | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.442 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.442 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.442 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.442 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 4fkl | CK2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.442 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.441 | |
| 2w17 | I19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.441 | |
| 3ekw | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3i2l | 2NC | Protease | / | 0.441 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.441 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3pwr | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4ema | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.441 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.441 | |
| 4ktc | 1X3 | Genome polyprotein | 3.4.21.98 | 0.441 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.441 | |
| 4pl4 | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.441 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 5bmv | VLB | Tubulin alpha-1B chain | / | 0.441 | |
| 5bmv | VLB | Tubulin beta chain | / | 0.441 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1sh9 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.440 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2e8h | SAH | Diphthine synthase | / | 0.440 | |
| 2ih2 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.440 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.440 | |
| 3djk | G55 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3dtw | A96 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 3gds | VAL_TYR_TYR_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.440 | |
| 3ieu | GDP | GTPase Era | / | 0.440 | |
| 3mje | NDP | AmphB | / | 0.440 | |
| 3pwm | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.440 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.440 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.440 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.440 | |
| 4fxf | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.440 | |
| 4o4e | ATP | Kinase | / | 0.440 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.440 |