sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1bfd | TPP | Benzoylformate decarboxylase | 4.1.1.7 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1bfd | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 1.000 | |
| 2fwn | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.761 | |
| 4qel | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.756 | |
| 5dgt | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.756 | |
| 4ju8 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.716 | |
| 4mzx | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.659 | |
| 4jd5 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.623 | |
| 4mq5 | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.608 | |
| 4gm0 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.593 | |
| 4ju9 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.591 | |
| 4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.587 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.574 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.573 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.570 | |
| 4k9p | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.563 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.560 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.548 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.536 | |
| 4juc | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.527 | |
| 4gm1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.502 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.492 | |
| 4mpp | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.491 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.486 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.482 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.482 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.481 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.480 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.480 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.480 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.478 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.478 | |
| 4zol | GTP | Tubulin alpha-1B chain | / | 0.477 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.476 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.474 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.474 | |
| 4y38 | 0A9 | Endothiapepsin | 3.4.23.22 | 0.474 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.474 | |
| 4wbn | GTP | Tubulin alpha-1B chain | / | 0.473 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.472 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.471 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.469 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.469 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.469 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.469 | |
| 1iy8 | NAD | Levodione reductase | / | 0.468 | |
| 2uyi | ADP | Kinesin-like protein KIF11 | / | 0.468 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.468 | |
| 3zcs | CAW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.468 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.467 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.467 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.466 | |
| 3ua8 | 08W | Glutamate receptor 2 | / | 0.466 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.465 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.465 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.465 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.464 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.464 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.463 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.463 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.463 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.463 | |
| 3daa | PDD | D-alanine aminotransferase | 2.6.1.21 | 0.462 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.462 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.462 | |
| 4o4l | GTP | Tubulin alpha-1B chain | / | 0.462 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.460 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.460 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.460 | |
| 2wb2 | FAD | RE11660p | / | 0.460 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.460 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.460 | |
| 4ihj | GTP | Tubulin alpha-1B chain | / | 0.460 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.459 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.459 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.459 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.459 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.458 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.458 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.458 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.457 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.457 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.457 | |
| 5a3b | APR | SIR2 family protein | / | 0.457 | |
| 5la6 | GTP | Tubulin alpha-1B chain | / | 0.457 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.456 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.456 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.456 | |
| 3ieu | GDP | GTPase Era | / | 0.456 | |
| 4y4j | LNR | Endothiapepsin | 3.4.23.22 | 0.456 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.455 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.455 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.455 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.455 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.455 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.455 | |
| 4o4i | GTP | Tubulin alpha-1B chain | / | 0.455 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.455 | |
| 1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.454 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.454 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.454 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.454 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.454 | |
| 5a3c | NAD | SIR2 family protein | / | 0.454 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.453 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.453 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.453 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.453 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.453 | |
| 3ll9 | ADP | Isopentenyl phosphate kinase | / | 0.453 | |
| 3o3p | GDD | Glycosyl transferase, family 2 | / | 0.453 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.452 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.452 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.451 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.451 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.451 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.451 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.451 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.450 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.450 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.450 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.450 | |
| 2pk3 | GDD | GDP-6-deoxy-D-mannose reductase | / | 0.450 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.450 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.450 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.450 | |
| 3r6c | 17N | Anthranilate phosphoribosyltransferase | / | 0.450 | |
| 5c3j | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.450 | |
| 5c3j | UQ1 | Succinate dehydrogenase cytochrome b560 | / | 0.450 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.449 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.449 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.449 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.449 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 4m10 | ICD | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.449 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.449 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.448 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.448 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.448 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 3pm4 | F5N | Endothiapepsin | 3.4.23.22 | 0.448 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.448 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.448 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.448 | |
| 5dp2 | NAP | CurF | / | 0.448 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.447 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.447 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.447 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.447 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.447 | |
| 2hu4 | G39 | Neuraminidase | / | 0.447 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.447 | |
| 4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.446 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.446 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.446 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 3a3g | DLZ | Lumazine protein | / | 0.446 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.446 | |
| 3prs | RIT | Endothiapepsin | 3.4.23.22 | 0.446 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.446 | |
| 1by5 | GLY_GLY_GLY_AHO_AHO_AHO_FE | Ferrichrome-iron receptor | / | 0.445 | |
| 1kqg | MGD | Formate dehydrogenase, nitrate-inducible, major subunit | 1.1.5.6 | 0.445 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 3iwj | NAD | Aminoaldehyde dehydrogenase | / | 0.445 | |
| 3jvv | ACP | Twitching mobility protein | / | 0.445 | |
| 3wag | TYD | Glycosyltransferase | / | 0.445 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.445 | |
| 4tuy | GTP | Tubulin alpha-1B chain | / | 0.445 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 5a8a | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.445 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.444 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.444 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.444 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.444 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.444 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.444 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.444 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 4yd7 | F5N | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.444 | |
| 6req | 3CP | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.444 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.443 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.443 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.443 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.443 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.443 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.443 | |
| 3p8z | 36A | Genome polyprotein | 2.1.1.56 | 0.443 | |
| 3ska | 053 | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.443 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
| 4hxm | 1A8 | Bromodomain-containing protein 4 | / | 0.443 | |
| 4kqq | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.443 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 5eso | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.443 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.442 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.442 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.442 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.442 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.442 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.442 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.442 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.441 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 1zdw | FLV | Prenyltransferase | / | 0.441 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.441 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.441 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.441 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3ha7 | B32 | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.441 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.441 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.441 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.441 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.441 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.440 | |
| 1e2n | RCA | Thymidine kinase | / | 0.440 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.440 | |
| 2ejz | SAH | Diphthine synthase | / | 0.440 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.440 | |
| 3ju8 | NAD | N-succinylglutamate 5-semialdehyde dehydrogenase | 1.2.1.71 | 0.440 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3pi0 | F91 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.440 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.440 | |
| 3x21 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.440 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.440 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.440 | |
| 5c41 | ACP | Ribokinase | / | 0.440 |