sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 1.000 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.657 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.644 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.638 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.623 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.619 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.611 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.606 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.584 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.583 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.578 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.565 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.555 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.507 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.502 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.489 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.488 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.488 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.487 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.486 | |
| 1fml | RTL | Retinol dehydratase | / | 0.485 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.484 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.484 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.482 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.482 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.481 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.481 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.480 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.480 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.477 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.476 | |
| 1c7o | PPG | Hemolysin | / | 0.475 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.475 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.474 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.473 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.473 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.473 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.473 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.472 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.471 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.471 | |
| 1lke | DOG | Bilin-binding protein | / | 0.469 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.469 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.469 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.469 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.469 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.469 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.468 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.468 | |
| 4jyz | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.468 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.467 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.466 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.466 | |
| 3eks | CY9 | Actin-5C | / | 0.466 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.466 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.465 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.464 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.463 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4h6p | FMN | Chromate reductase | / | 0.462 | |
| 4n1g | CEI | Obelin | / | 0.462 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.462 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.461 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.460 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.459 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.459 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.459 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.459 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.459 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.458 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.458 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.458 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.457 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.457 | |
| 3hf8 | ML0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.457 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.457 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.457 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.456 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.456 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1thz | 326 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.455 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.455 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 4ha6 | PXM | Pyridoxine 4-oxidase | / | 0.455 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.453 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.453 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.453 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 4j7g | TRH | PCZA361.3 | / | 0.453 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1osv | CHC | Bile acid receptor | / | 0.452 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.452 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.452 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.451 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.451 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 3r94 | FLR | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.451 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.450 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.450 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.450 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.449 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.449 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.449 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.449 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.449 | |
| 3b9l | AZZ | Serum albumin | / | 0.449 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 4boe | CLR | Japanin | / | 0.449 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.448 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.448 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.448 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.448 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 3e30 | ED4 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.448 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 1o1t | 2NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.447 | |
| 2rcw | AAI | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 3c4h | DRL | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.447 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.447 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.447 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.447 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.446 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.446 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.446 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.446 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.446 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.445 | |
| 2r97 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.445 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.445 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.444 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.444 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.444 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.444 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 3c1o | NAP | Eugenol synthase | / | 0.444 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 4hcy | 0YN | Transketolase | / | 0.444 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.444 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.443 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.443 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.443 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 3hgg | CHD | CmeR | / | 0.443 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.443 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.443 | |
| 4h1q | 0XX | Matrix metalloproteinase-9 | 3.4.24.35 | 0.443 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.443 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.443 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.443 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.442 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.442 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.442 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.442 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.441 | |
| 1uhj | CZB | Aequorin-2 | / | 0.441 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.441 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.441 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.441 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.440 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.440 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.440 | |
| 2b4d | COA | Diamine acetyltransferase 1 | / | 0.440 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.440 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.440 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.440 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.440 |