Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3rpy27ZCyclin-dependent kinase 22.7.11.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3rpy27ZCyclin-dependent kinase 22.7.11.221.000
3rmf20ZCyclin-dependent kinase 22.7.11.220.795
3ral04ZCyclin-dependent kinase 22.7.11.220.698
3s1h56ZCyclin-dependent kinase 22.7.11.220.641
3rak03ZCyclin-dependent kinase 22.7.11.220.622
3sw418KCyclin-dependent kinase 22.7.11.220.607
3r9dX6BCyclin-dependent kinase 22.7.11.220.602
3rk507ZCyclin-dependent kinase 22.7.11.220.586
3ezvEZVCyclin-dependent kinase 22.7.11.220.583
4fkg4CKCyclin-dependent kinase 22.7.11.220.581
1pxlCK4Cyclin-dependent kinase 22.7.11.220.576
4bgh3I6Cyclin-dependent kinase 22.7.11.220.576
3qxpX64Cyclin-dependent kinase 22.7.11.220.574
2w06FRVCyclin-dependent kinase 22.7.11.220.571
1p2a5BNCyclin-dependent kinase 22.7.11.220.570
4ek610KCyclin-dependent kinase 22.7.11.220.565
4fkj11KCyclin-dependent kinase 22.7.11.220.564
3uli1N3Cyclin-dependent kinase 22.7.11.220.562
3unk0BYCyclin-dependent kinase 22.7.11.220.562
4fkq42KCyclin-dependent kinase 22.7.11.220.562
3rk708ZCyclin-dependent kinase 22.7.11.220.560
3qtzX42Cyclin-dependent kinase 22.7.11.220.557
1urwI1PCyclin-dependent kinase 22.7.11.220.554
4fko20KCyclin-dependent kinase 22.7.11.220.554
1ke5LS1Cyclin-dependent kinase 22.7.11.220.552
3qu0X40Cyclin-dependent kinase 22.7.11.220.551
2xmyCDKCyclin-dependent kinase 22.7.11.220.550
3qtxX43Cyclin-dependent kinase 22.7.11.220.550
4fkr45KCyclin-dependent kinase 22.7.11.220.550
3rzb02ZCyclin-dependent kinase 22.7.11.220.549
4acm7YGCyclin-dependent kinase 22.7.11.220.547
3py0SU9Cyclin-dependent kinase 22.7.11.220.546
1pxmCK5Cyclin-dependent kinase 22.7.11.220.543
3qzgX67Cyclin-dependent kinase 22.7.11.220.541
3wblPDYCyclin-dependent kinase 22.7.11.220.541
3r1sX73Cyclin-dependent kinase 22.7.11.220.538
1v1k3FPCyclin-dependent kinase 22.7.11.220.535
1y91CT9Cyclin-dependent kinase 22.7.11.220.535
1pxkCK3Cyclin-dependent kinase 22.7.11.220.534
2r64740Cyclin-dependent kinase 22.7.11.220.534
2w17I19Cyclin-dependent kinase 22.7.11.220.533
2uznC96Cyclin-dependent kinase 22.7.11.220.532
1ke6LS2Cyclin-dependent kinase 22.7.11.220.531
1ke8LS4Cyclin-dependent kinase 22.7.11.220.531
1oitHDTCyclin-dependent kinase 22.7.11.220.531
3qtuX44Cyclin-dependent kinase 22.7.11.220.531
1oiyN41Cyclin-dependent kinase 22.7.11.220.529
2vv9IM9Cyclin-dependent kinase 22.7.11.220.528
4fx360KCyclin-dependent kinase 22.7.11.220.528
3qtrX36Cyclin-dependent kinase 22.7.11.220.527
1ke9LS5Cyclin-dependent kinase 22.7.11.220.526
1vyzN5BCyclin-dependent kinase 22.7.11.220.526
3qqfX07Cyclin-dependent kinase 22.7.11.220.526
3unj0BXCyclin-dependent kinase 22.7.11.220.526
2w05FRTCyclin-dependent kinase 22.7.11.220.525
1fvv107Cyclin-dependent kinase 22.7.11.220.524
1gih1PUCyclin-dependent kinase 22.7.11.220.524
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.522
3r8zZ63Cyclin-dependent kinase 22.7.11.220.521
3roy22ZCyclin-dependent kinase 22.7.11.220.521
3s0o50ZCyclin-dependent kinase 22.7.11.220.521
4fkt48KCyclin-dependent kinase 22.7.11.220.520
3qxoX65Cyclin-dependent kinase 22.7.11.220.519
2btsU32Cyclin-dependent kinase 22.7.11.220.518
3r7uX96Cyclin-dependent kinase 22.7.11.220.518
1w0xOLOCyclin-dependent kinase 22.7.11.220.517
1ykr628Cyclin-dependent kinase 22.7.11.220.516
1gii1PUCyclin-dependent kinase 22.7.11.220.515
2iw84SPCyclin-dependent kinase 22.7.11.220.515
2r3lSCWCyclin-dependent kinase 22.7.11.220.515
4ek816KCyclin-dependent kinase 22.7.11.220.515
3qzhX69Cyclin-dependent kinase 22.7.11.220.514
3r9oZ71Cyclin-dependent kinase 22.7.11.220.514
3rjc06ZCyclin-dependent kinase 22.7.11.220.514
3rpv26ZCyclin-dependent kinase 22.7.11.220.514
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.513
1oi9N20Cyclin-dependent kinase 22.7.11.220.511
4fkpLS5Cyclin-dependent kinase 22.7.11.220.511
2c6o4SPCyclin-dependent kinase 22.7.11.220.510
3ti1B49Cyclin-dependent kinase 22.7.11.220.510
4fkv61KCyclin-dependent kinase 22.7.11.220.510
2w1hL0FCyclin-dependent kinase 22.7.11.220.509
4ez30S0Cyclin-dependent kinase 22.7.11.220.508
1fvt106Cyclin-dependent kinase 22.7.11.220.507
1ke7LS3Cyclin-dependent kinase 22.7.11.220.507
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.507
2a0cCK9Cyclin-dependent kinase 22.7.11.220.506
2wihP48Cyclin-dependent kinase 22.7.11.220.506
4fkw62KCyclin-dependent kinase 22.7.11.220.506
3r71X86Cyclin-dependent kinase 22.7.11.220.505
3rm719ZCyclin-dependent kinase 22.7.11.220.504
1di8DTQCyclin-dependent kinase 22.7.11.220.503
3qzfX66Cyclin-dependent kinase 22.7.11.220.503
1oguST8Cyclin-dependent kinase 22.7.11.220.502
3rni21ZCyclin-dependent kinase 22.7.11.220.502
3sqq99ZCyclin-dependent kinase 22.7.11.220.502
2uzoC62Cyclin-dependent kinase 22.7.11.220.501
4fks46KCyclin-dependent kinase 22.7.11.220.501
3lfnA27Cyclin-dependent kinase 22.7.11.220.500
3r7iX9ICyclin-dependent kinase 22.7.11.220.500
3r9hZ67Cyclin-dependent kinase 22.7.11.220.499
2bheBRYCyclin-dependent kinase 22.7.11.220.498
3s2pPMUCyclin-dependent kinase 22.7.11.220.497
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.495
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.495
2fvdLIACyclin-dependent kinase 22.7.11.220.494
2c6iDT1Cyclin-dependent kinase 22.7.11.220.493
2j9mPY8Cyclin-dependent kinase 22.7.11.220.493
3qruX19Cyclin-dependent kinase 22.7.11.220.493
3qtqX35Cyclin-dependent kinase 22.7.11.220.492
2r3iSCFCyclin-dependent kinase 22.7.11.220.491
3iggEFQCyclin-dependent kinase 22.7.11.220.491
1oirHDYCyclin-dependent kinase 22.7.11.220.490
1pkdUCNCyclin-dependent kinase 22.7.11.220.490
3rkb12ZCyclin-dependent kinase 22.7.11.220.490
4qmpDKISerine/threonine-protein kinase 242.7.11.10.490
1e9hINRCyclin-dependent kinase 22.7.11.220.489
2r3kSCQCyclin-dependent kinase 22.7.11.220.489
3qtwX3ACyclin-dependent kinase 22.7.11.220.487
3sw719KCyclin-dependent kinase 22.7.11.220.486
3rk909ZCyclin-dependent kinase 22.7.11.220.485
3raiX85Cyclin-dependent kinase 22.7.11.220.484
4fki09KCyclin-dependent kinase 22.7.11.220.484
1oiqHDUCyclin-dependent kinase 22.7.11.220.483
3r73X87Cyclin-dependent kinase 22.7.11.220.483
3r8lZ30Cyclin-dependent kinase 22.7.11.220.483
3r6xX84Cyclin-dependent kinase 22.7.11.220.482
4lyn1YGCyclin-dependent kinase 22.7.11.220.482
2btrU73Cyclin-dependent kinase 22.7.11.220.481
3tiz3TICyclin-dependent kinase 22.7.11.220.481
2b54D05Cyclin-dependent kinase 22.7.11.220.480
2wxvWXVCyclin-dependent kinase 22.7.11.220.480
1g5sI17Cyclin-dependent kinase 22.7.11.220.479
2bhhRYUCyclin-dependent kinase 22.7.11.220.479
2i40BLZCyclin-dependent kinase 22.7.11.220.479
3ddpRC8Cyclin-dependent kinase 22.7.11.220.479
3ezrEZRCyclin-dependent kinase 22.7.11.220.479
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.477
3qqkX02Cyclin-dependent kinase 22.7.11.220.475
1ckpPVBCyclin-dependent kinase 22.7.11.220.474
1r78FMDCyclin-dependent kinase 22.7.11.220.474
1vyw292Cyclin-dependent kinase 22.7.11.220.474
1y8yCT7Cyclin-dependent kinase 22.7.11.220.474
2duv371Cyclin-dependent kinase 22.7.11.220.474
1aq1STUCyclin-dependent kinase 22.7.11.220.473
3r7vZ02Cyclin-dependent kinase 22.7.11.220.473
3tnwF18Cyclin-dependent kinase 22.7.11.220.473
4eok4SPCyclin-dependent kinase 22.7.11.220.472
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.471
2c6tDT5Cyclin-dependent kinase 22.7.11.220.471
3fz1B98Cyclin-dependent kinase 22.7.11.220.471
1gij2PUCyclin-dependent kinase 22.7.11.220.470
3qwjX6ACyclin-dependent kinase 22.7.11.220.470
3r1qX75Cyclin-dependent kinase 22.7.11.220.469
1pxpCK8Cyclin-dependent kinase 22.7.11.220.468
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.468
2r3mSCXCyclin-dependent kinase 22.7.11.220.468
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.468
3qqhX0ACyclin-dependent kinase 22.7.11.220.468
1dm2HMDCyclin-dependent kinase 22.7.11.220.467
3pj8404Cyclin-dependent kinase 22.7.11.220.467
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.467
1h1s4SPCyclin-dependent kinase 22.7.11.220.466
3qx2X63Cyclin-dependent kinase 22.7.11.220.466
2vttLZDCyclin-dependent kinase 22.7.11.220.465
3r1yX76Cyclin-dependent kinase 22.7.11.220.465
3r7eX88Cyclin-dependent kinase 22.7.11.220.465
2c5nCK8Cyclin-dependent kinase 22.7.11.220.464
3qwkX62Cyclin-dependent kinase 22.7.11.220.464
3lfsA07Cyclin-dependent kinase 22.7.11.220.463
2r3p3SCCyclin-dependent kinase 22.7.11.220.462
3nynSGVG protein-coupled receptor kinase 62.7.11.160.462
4au8Z3RCyclin-dependent-like kinase 52.7.11.10.462
4bcmT7ZCyclin-dependent kinase 22.7.11.220.462
2wpa889Cyclin-dependent kinase 22.7.11.220.461
2vu3LZECyclin-dependent kinase 22.7.11.220.460
2b55D31Cyclin-dependent kinase 22.7.11.220.459
2iw94SPCyclin-dependent kinase 22.7.11.220.459
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.459
2c6kDT2Cyclin-dependent kinase 22.7.11.220.458
3ig7EFPCyclin-dependent kinase 22.7.11.220.458
3pxyJWSCyclin-dependent kinase 22.7.11.220.458
3ql8X01Cyclin-dependent kinase 22.7.11.220.458
3r83Z14Cyclin-dependent kinase 22.7.11.220.457
2uzbC75Cyclin-dependent kinase 22.7.11.220.456
1h1r6CPCyclin-dependent kinase 22.7.11.220.455
3nux3NVCyclin-dependent kinase 62.7.11.220.455
3r7yZ04Cyclin-dependent kinase 22.7.11.220.455
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.455
2x1nX1NCyclin-dependent kinase 22.7.11.220.454
2xnbY8LCyclin-dependent kinase 22.7.11.220.454
2pvnP63Casein kinase II subunit alpha2.7.11.10.453
2vtsLZCCyclin-dependent kinase 22.7.11.220.453
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.453
4eol1ROCyclin-dependent kinase 22.7.11.220.453
4eor4SPCyclin-dependent kinase 22.7.11.220.453
2b53D23Cyclin-dependent kinase 22.7.11.220.452
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.451
4erwSTUCyclin-dependent kinase 22.7.11.220.451
2cchATPCyclin-dependent kinase 22.7.11.220.450
3lfqA28Cyclin-dependent kinase 22.7.11.220.450
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.450
1unlRRCCyclin-dependent-like kinase 52.7.11.10.449
2a4lRRCCyclin-dependent kinase 22.7.11.220.449
3r8pZ46Cyclin-dependent kinase 22.7.11.220.449
1h0w207Cyclin-dependent kinase 22.7.11.220.448
3ddqRRCCyclin-dependent kinase 22.7.11.220.448
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.448
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.447
2c5yMTWCyclin-dependent kinase 22.7.11.220.447
2uzeC95Cyclin-dependent kinase 22.7.11.220.447
3le62BZCyclin-dependent kinase 22.7.11.220.447
3r28XA0Cyclin-dependent kinase 22.7.11.220.447
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.446
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.446
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.445
2r3fSC8Cyclin-dependent kinase 22.7.11.220.445
3dogNNNCyclin-dependent kinase 22.7.11.220.445
3s00Z60Cyclin-dependent kinase 22.7.11.220.445
3mvl38PMitogen-activated protein kinase 14/0.443
3qqlX03Cyclin-dependent kinase 22.7.11.220.443
3rpo24ZCyclin-dependent kinase 22.7.11.220.443
4aua4AUCyclin-dependent kinase 62.7.11.220.443
4bcpT3CCyclin-dependent kinase 22.7.11.220.443
3my5RFZCyclin-dependent kinase 22.7.11.220.442
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.442
1pyePM1Cyclin-dependent kinase 22.7.11.220.441
2r3q5SCCyclin-dependent kinase 22.7.11.220.441
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.441
3be9P04Casein kinase II subunit alpha2.7.11.10.441
2r3jSCJCyclin-dependent kinase 22.7.11.220.440
2vthLZ2Cyclin-dependent kinase 22.7.11.220.440
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.440
3bhy7CPDeath-associated protein kinase 3/0.440
4kd11QKCyclin-dependent kinase 22.7.11.220.440