scPDB - Distribution of Binding site Similarity values of 3ik7 entry / Site 4

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3ik7	BOB	Glutathione S-transferase A4	2.5.1.18

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3ik7	BOB	Glutathione S-transferase A4	2.5.1.18	1.000
3ik9	BOB	Glutathione S-transferase A1	2.5.1.18	0.532
3sni	546	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.506
2r6k	GTX	Glutathione S-transferase A1	2.5.1.18	0.492
3l0h	GTX	Glutathione S-transferase A1	2.5.1.18	0.491
4j8t	DOG	Uncharacterized PhzA/B-like protein PA3332	/	0.491
1q0z	AKA	Aclacinomycin methylesterase RdmC	3.1.1.95	0.487
3sn7	540	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.480
2zs9	ADP	Pantothenate kinase	2.7.1.33	0.479
2jl1	NAP	Triphenylmethane reductase	/	0.478
1xom	CIO	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.476
2ouu	35G	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.476
3ktl	GTX	Glutathione S-transferase A1	2.5.1.18	0.474
4fcb	0T7	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.474
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.472
1ro9	8BR	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.472
2zsb	ADP	Pantothenate kinase	2.7.1.33	0.471
1gsf	EAA	Glutathione S-transferase A1	2.5.1.18	0.470
4a1o	AMZ	Bifunctional purine biosynthesis protein PurH	2.1.2.3	0.470
1pl2	ABY	Glutathione S-transferase A1	2.5.1.18	0.469
1gul	GLY_GGL_ICY	Glutathione S-transferase A4	2.5.1.18	0.467
1obn	ASV	Isopenicillin N synthase	1.21.3.1	0.467
1q0r	AKT	Aclacinomycin methylesterase RdmC	3.1.1.95	0.467
1dgg	NDP	Catalase	1.11.1.6	0.466
1gg5	E09	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.466
1h69	ARH	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.466
1y2e	5DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.466
3uyk	0CX	Probable NDP-rhamnosyltransferase	/	0.463
1oc1	ASV	Isopenicillin N synthase	1.21.3.1	0.462
1x8l	OXR	Retinol dehydratase	/	0.462
1el4	CTZ	Obelin	/	0.461
3h3s	H15	Collagen type IV alpha-3-binding protein	/	0.461
3dd1	25D	Glycogen phosphorylase, liver form	2.4.1.1	0.460
4gxs	0YS	Glutamate receptor 2	/	0.460
3c0g	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.458
4lm4	JPZ	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.458
4uug	PXG	Branched-chain amino acid aminotransferase, putative	/	0.458
5irn	ADP	Nucleotide binding oligomerization domain containing 2	/	0.458
1xon	PIL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.457
2a5h	SAM	L-lysine 2,3-aminomutase	5.4.3.2	0.457
3iak	EV1	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.457
5p2p	DHG	Phospholipase A2, major isoenzyme	3.1.1.4	0.457
1soj	IBM	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	3.1.4.17	0.456
3zhv	TDW	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.456
1dgb	NDP	Catalase	1.11.1.6	0.455
1ry0	PG2	Aldo-keto reductase family 1 member C3	/	0.455
2vd0	D27	Hematopoietic prostaglandin D synthase	/	0.455
1i5r	HYC	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.454
2nn7	M29	Carbonic anhydrase 1	4.2.1.1	0.454
2our	CMP	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.454
2ouy	CMP	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.454
2rqf	JH3	Hemolymph juvenile hormone binding protein	/	0.454
4hf4	15H	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.454
4llk	MEW	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.454
2vbp	VB1	Isopenicillin N synthase	1.21.3.1	0.453
2vcw	ZZA	Hematopoietic prostaglandin D synthase	/	0.453
3h3t	16H	Collagen type IV alpha-3-binding protein	/	0.453
3jsx	CC2	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.453
3k4s	0MO	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.453
3vjl	W94	Dipeptidyl peptidase 4	/	0.453
1b48	HAG	Glutathione S-transferase A4	2.5.1.18	0.452
2zs8	ADP	Pantothenate kinase	2.7.1.33	0.452
3kxo	KXO	Hematopoietic prostaglandin D synthase	/	0.452
2a4x	BLM	Mitomycin-binding protein	/	0.451
2g1o	2IG	Renin	3.4.23.15	0.451
2vcx	D26	Hematopoietic prostaglandin D synthase	/	0.451
2yp0	OVE	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.451
3k1w	BFX	Renin	3.4.23.15	0.451
4dxl	C5P	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	/	0.450
4kp6	1S1	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.450
1dgh	NDP	Catalase	1.11.1.6	0.449
1y2b	DEE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.449
2ixk	TDO	dTDP-4-dehydrorhamnose 3,5-epimerase	5.1.3.13	0.449
2vqo	TFG	Histone deacetylase 4	3.5.1.98	0.449
3ihg	VAK	Aklavinone 12-hydroxylase RdmE	/	0.449
4eqk	MGT	Polymerase basic protein 2	/	0.449
4zzi	1NS	NAD-dependent protein deacetylase sirtuin-1	3.5.1	0.449
4c1i	EH9	cGMP-dependent 3',5'-cyclic phosphodiesterase	3.1.4.17	0.448
4dbs	0HV	Aldo-keto reductase family 1 member C3	/	0.448
4f0r	MTA	5-methylthioadenosine/S-adenosylhomocysteine deaminase	/	0.448
5cc9	DDF	Dihydrofolate reductase	1.5.1.3	0.448
2qo5	CHD	Fatty acid-binding protein 10-A, liver basic	/	0.447
3h3q	H13	Collagen type IV alpha-3-binding protein	/	0.447
3w0u	HPW	Lactoylglutathione lyase	4.4.1.5	0.447
1y2k	7DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.446
4hw3	19G	Induced myeloid leukemia cell differentiation protein Mcl-1	/	0.446
4uy6	SAH	Histidine N-alpha-methyltransferase	/	0.446
1fxu	GU7	Purine nucleoside phosphorylase	2.4.2.1	0.445
2acl	L05	Oxysterols receptor LXR-alpha	/	0.445
1aqu	EST	Estrogen sulfotransferase, testis isoform	2.8.2.4	0.444
1tow	CRZ	Fatty acid-binding protein, adipocyte	/	0.444
1uhh	CZP	Aequorin-2	/	0.444
2gpj	FAD	Siderophore-interacting protein	/	0.444
4fcd	0T6	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.444
4ise	1FW	Glucokinase	2.7.1.2	0.444
1rx0	FAD	Isobutyryl-CoA dehydrogenase, mitochondrial	1.3.99	0.443
2a0x	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.443
4obu	PLP	Pyridoxal-dependent decarboxylase domain protein	/	0.443
4pgt	GBX	Glutathione S-transferase P	2.5.1.18	0.443
1enp	NAD	Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic	1.3.1.9	0.442
1fml	RTL	Retinol dehydratase	/	0.442
1vf3	GDN	Glutathione S-transferase 3	2.5.1.18	0.442
3d3p	20A	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.442
1k3y	GTX	Glutathione S-transferase A1	2.5.1.18	0.441
1mxf	MTX	Putative pteridine reductase 2	/	0.441
1uho	VDN	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.441
1ut6	A8N	Acetylcholinesterase	3.1.1.7	0.441
2g25	TDK	Pyruvate dehydrogenase E1 component	1.2.4.1	0.441
2j3q	TFL	Acetylcholinesterase	3.1.1.7	0.441
2y0j	AXC	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.441
3k2f	NKX	Carbonic anhydrase 2	4.2.1.1	0.441
4k8s	1QT	Beta-secretase 1	3.4.23.46	0.441
4mr7	2BV	Gamma-aminobutyric acid type B receptor subunit 1	/	0.441
4r5w	XAV	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.441
8cat	NDP	Catalase	1.11.1.6	0.441
2dxi	ATP	Glutamate--tRNA ligase	6.1.1.17	0.440
3hl0	NAD	Maleylacetate reductase	/	0.440
3n14	FMN	Xenobiotic reductase	/	0.440
3wav	DWV	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	3.1.4.39	0.440
4b68	NAP	L-ornithine N(5)-monooxygenase	/	0.440
4eso	NAP	Putative oxidoreductase	/	0.440