Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3f88 | 3HT | Glycogen synthase kinase-3 beta | 2.7.11.26 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3f88 | 3HT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 1.000 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.614 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.588 | |
| 4acd | GR9 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.583 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.576 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.575 | |
| 4afj | SJJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.568 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.545 | |
| 4b7t | CWT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.542 | |
| 3du8 | 553 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.540 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.539 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.538 | |
| 3gb2 | G3B | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.537 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.533 | |
| 3f7z | 34O | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.531 | |
| 2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.529 | |
| 3zrm | ZRM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.526 | |
| 3q3b | 55E | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.522 | |
| 1uv5 | BRW | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.521 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.521 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.521 | |
| 1pyx | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.519 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.515 | |
| 3sd0 | TSK | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.513 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.509 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.508 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.508 | |
| 3zrk | ZRK | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.507 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.505 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.504 | |
| 3dtc | VIN | Mitogen-activated protein kinase kinase kinase 9 | 2.7.11.25 | 0.503 | |
| 4j71 | 1JX | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.503 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.502 | |
| 4nm0 | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.502 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.500 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.500 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.498 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.493 | |
| 2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.492 | |
| 3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.490 | |
| 3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.490 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.489 | |
| 4i0t | 1B6 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.489 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.488 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.488 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.486 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.486 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.485 | |
| 1q4l | 679 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.485 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.485 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.485 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.484 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.483 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.482 | |
| 4mbl | 26L | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.482 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.482 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.481 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.480 | |
| 3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.479 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.479 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.478 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.478 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.477 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.477 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.476 | |
| 3blr | CPB | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.475 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.474 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.474 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.473 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.473 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.473 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.473 | |
| 4oth | DRN | Serine/threonine-protein kinase N1 | / | 0.473 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 1pme | SB2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.471 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.471 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.471 | |
| 3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.471 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.469 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.469 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.468 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.467 | |
| 3zrl | ZRL | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.467 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.467 | |
| 1mq4 | ADP | Aurora kinase A | 2.7.11.1 | 0.466 | |
| 3eb0 | DRK | Uncharacterized protein | / | 0.466 | |
| 5dgz | L20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.465 | |
| 1q3d | STU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.464 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.464 | |
| 4nm7 | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.464 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.463 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.463 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.463 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.463 | |
| 5dp2 | NAP | CurF | / | 0.463 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.462 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.462 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.462 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.461 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.461 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.461 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.461 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.461 | |
| 4nm5 | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.461 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.460 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.460 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.460 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.459 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.459 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.458 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.458 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.458 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.458 | |
| 2chl | DKI | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.457 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.457 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.457 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.456 | |
| 3zdi | UGJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.456 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.456 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.456 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.455 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.455 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.454 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.454 | |
| 2jdv | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.454 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.454 | |
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.454 | |
| 4b1f | KRH | Glutamate racemase | / | 0.454 | |
| 4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.453 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.453 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 4dfl | 0K0 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.453 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.453 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.453 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.453 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.452 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.452 | |
| 1ppj | ANY | Cytochrome b | / | 0.452 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.452 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.452 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.452 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.452 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.452 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.452 | |
| 4j1r | I5R | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 1ao0 | 5GP | Amidophosphoribosyltransferase | / | 0.451 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 1ryw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.451 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.451 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.451 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.451 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.451 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.451 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.451 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.451 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.450 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2wmw | ZYW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 3of4 | FMN | Nitroreductase | / | 0.450 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.450 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.449 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.449 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.449 | |
| 2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.449 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.449 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 4b8m | VX6 | Aurora kinase B-A | 2.7.11.1 | 0.449 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.449 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.449 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.448 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 3js2 | VM1 | Fibroblast growth factor receptor 1 | / | 0.448 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.448 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.448 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.447 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.447 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.447 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.447 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.447 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.447 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 4ix4 | ADP | Uncharacterized protein | / | 0.447 | |
| 4n6z | 2HW | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.447 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.447 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.446 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.446 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.446 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.446 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.446 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 5dt4 | ATP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.445 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.445 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.444 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 3ddq | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.444 | |
| 3w18 | N13 | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.443 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.443 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.443 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.443 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.443 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1tw2 | ERT | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.442 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.442 | |
| 3arv | SAU | Chitinase A | / | 0.442 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.442 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.442 | |
| 3vf9 | 477 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.442 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4g3e | 0WC | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.442 | |
| 4g6o | E28 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.442 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.442 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.442 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.441 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.441 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.441 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.441 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 3ezr | EZR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.441 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.441 | |
| 4zvm | DM2 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1hk1 | T44 | Serum albumin | / | 0.440 | |
| 1hk3 | T44 | Serum albumin | / | 0.440 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.440 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.440 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.440 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 3hu1 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.440 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.440 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 3uxe | 465 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.440 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.440 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 5dn3 | ATP | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.440 |