sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ziq | 26U | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 1.000 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.850 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.837 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.785 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.765 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.765 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.759 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.756 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.742 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.735 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.735 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.734 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.712 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.702 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.679 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.677 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.670 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.663 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.660 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.658 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.655 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.652 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.648 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.646 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.642 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.641 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.641 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.640 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.638 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.634 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.630 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.629 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.628 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.627 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.627 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.625 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.625 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.624 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.624 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.618 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.617 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.611 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.611 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.606 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.605 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.604 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.604 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.603 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.602 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.598 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.598 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.597 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.597 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.596 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.595 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.594 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.594 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.593 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.592 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.591 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.590 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.588 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.586 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.586 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.584 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.584 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.582 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.581 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.580 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.580 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.578 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.577 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.577 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.576 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.574 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.574 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.570 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.566 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.564 | |
| 1kts | C24 | Prothrombin | 3.4.21.5 | 0.561 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.557 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.557 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.556 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.555 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.550 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.550 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.549 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.545 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.544 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.543 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.540 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.537 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.535 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.535 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.534 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.534 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.531 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.531 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.527 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.525 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.524 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.521 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.518 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.518 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.518 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.514 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.513 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.513 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.511 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.511 | |
| 1zsk | 421 | Coagulation factor XI | 3.4.21.27 | 0.506 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.505 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.501 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.498 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.498 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.494 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.487 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.486 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.485 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 1sl3 | 170 | Prothrombin | 3.4.21.5 | 0.483 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.479 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.475 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.475 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.475 | |
| 3v2u | ATP | Protein GAL3 | / | 0.472 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.468 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.467 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.465 | |
| 2nr4 | FMN | Conserved protein | / | 0.465 | |
| 1wqv | PSM | Coagulation factor VII | 3.4.21.21 | 0.464 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.464 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.463 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.462 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2vqz | MGT | Polymerase basic protein 2 | / | 0.461 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.461 | |
| 3wag | TYD | Glycosyltransferase | / | 0.461 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.461 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.460 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.460 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.458 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.458 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.457 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.457 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.457 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.456 | |
| 1sqt | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.456 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.456 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.456 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.455 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.455 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.455 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.455 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.455 | |
| 5dp2 | NAP | CurF | / | 0.455 | |
| 1wli | FMN | FMN-binding protein | / | 0.454 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.454 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.453 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 3tg4 | SAM | N-lysine methyltransferase SMYD2 | / | 0.453 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.452 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 5ex0 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.452 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.451 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.451 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 1khe | GCP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.450 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.450 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3pdn | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.450 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.450 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.449 | |
| 2j4l | UTP | Uridylate kinase | 2.7.4.22 | 0.449 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 3v0x | ANH | Cationic trypsin | 3.4.21.4 | 0.449 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.449 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.448 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2viv | VG2 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.448 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.448 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.447 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.447 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.447 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.447 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.446 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.446 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.445 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.445 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.444 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.444 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.444 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.444 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.443 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.443 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.443 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.443 | |
| 2xvv | 9DN | Serum albumin | / | 0.443 | |
| 3q9o | NAD | Cholix toxin | 2.4.2.36 | 0.443 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.443 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.442 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2zp0 | PI0 | Coagulation factor VII | 3.4.21.21 | 0.442 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.442 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.442 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.442 | |
| 1cne | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.441 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.441 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.441 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.441 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.441 | |
| 2xls | NAP | Putative flavin-containing monooxygenase | / | 0.441 | |
| 3mo0 | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.441 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.441 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.441 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.441 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.440 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.440 | |
| 1pt5 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.440 | |
| 2o2y | TCL | Enoyl-ACP reductase | / | 0.440 | |
| 2p2m | PRX | Acetyl-coenzyme A synthetase | / | 0.440 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.440 | |
| 4fub | 4UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.440 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.440 |