sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2aib | ERG | Beta-elicitin cinnamomin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2aib | ERG | Beta-elicitin cinnamomin | / | 1.000 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.693 | |
| 2y03 | Y01 | Beta-1 adrenergic receptor | / | 0.522 | |
| 1osv | CHC | Bile acid receptor | / | 0.518 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.509 | |
| 2y00 | Y01 | Beta-1 adrenergic receptor | / | 0.505 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.501 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.498 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.495 | |
| 2y01 | Y01 | Beta-1 adrenergic receptor | / | 0.494 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.492 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.491 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.491 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.490 | |
| 2y02 | Y01 | Beta-1 adrenergic receptor | / | 0.490 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.490 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.489 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.487 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.486 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.486 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.484 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.484 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.481 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.480 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.479 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.479 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.479 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.479 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.478 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.477 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.477 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.477 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.476 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.476 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.476 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.475 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.474 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.474 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.473 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.473 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.472 | |
| 2xyn | VX6 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.472 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.472 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.472 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.471 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.471 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.471 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.471 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.471 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.471 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.470 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.469 | |
| 3zuy | TCH | Transporter | / | 0.469 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.468 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.468 | |
| 2jd0 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.468 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.468 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.468 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.468 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.467 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.467 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.467 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 2dji | FAD | Pyruvate oxidase | / | 0.466 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.466 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.466 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.465 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.464 | |
| 4oze | 24G | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.464 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.463 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.463 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.463 | |
| 1fbm | RTL | Cartilage oligomeric matrix protein | / | 0.462 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.462 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.462 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 3u1y | 03I | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.461 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.461 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.460 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.460 | |
| 3abi | NAD | Uncharacterized protein | / | 0.460 | |
| 3nal | DBK | Calcium-transporting ATPase | / | 0.460 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.460 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.460 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.460 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 3h1j | SMA | Cytochrome b | / | 0.459 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.459 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.459 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.459 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.458 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.458 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.458 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.458 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.458 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.458 | |
| 3w18 | N13 | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.458 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.457 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.457 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.457 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.457 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.456 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.456 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.456 | |
| 1v5e | FAD | Pyruvate oxidase | / | 0.456 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.456 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.456 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.456 | |
| 2oye | IM8 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.456 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.456 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.456 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.456 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.456 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.456 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.455 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.455 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.455 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.455 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.455 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.455 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.454 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.454 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.454 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.454 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.454 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.454 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.454 | |
| 5a3b | APR | SIR2 family protein | / | 0.454 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.453 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.453 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.452 | |
| 1pp9 | SMA | Cytochrome b | / | 0.452 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.452 | |
| 3i99 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.452 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.452 | |
| 3zxt | ACP | Death-associated protein kinase 1 | 2.7.11.1 | 0.452 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.452 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 4pd6 | URI | Nucleoside permease | / | 0.452 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.451 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.451 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.451 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.451 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.451 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.451 | |
| 5l7d | CLR | Smoothened homolog | / | 0.451 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.450 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.450 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1ppj | SMA | Cytochrome b | / | 0.450 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 2wet | FAD | Tryptophan 5-halogenase | / | 0.450 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.450 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.450 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.450 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.450 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.450 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.449 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.449 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.449 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.449 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.449 | |
| 3fcj | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.449 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.449 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.449 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.449 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.449 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.449 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.449 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.449 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.448 | |
| 3vs1 | VSA | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.448 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.448 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.448 | |
| 4l06 | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.448 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.448 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.448 | |
| 1kb9 | SMA | Cytochrome b | / | 0.447 | |
| 1kgj | FL8 | Transthyretin | / | 0.447 | |
| 1kk4 | ACO | Streptogramin A acetyltransferase | 2.3.1 | 0.447 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.447 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.447 | |
| 2gtm | LID | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.447 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.447 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.447 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.447 | |
| 3dei | RXB | Caspase-3 | 3.4.22.56 | 0.447 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.447 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.447 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.447 | |
| 4ez7 | 2AN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.447 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.447 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.447 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.446 | |
| 2ibz | SMA | Cytochrome b | / | 0.446 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.446 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 2qu6 | 857 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.446 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.446 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3iup | NDP | Possible NADH oxidoreductase | / | 0.446 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.446 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.446 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.446 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.446 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.446 | |
| 4u8n | FDA | UDP-galactopyranose mutase | / | 0.446 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.445 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2c6h | PXI | Cytochrome P450 monooxygenase PikC | / | 0.445 | |
| 2yaa | ATP | Death-associated protein kinase 2 | / | 0.445 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.445 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.445 | |
| 3mkh | FAD | Nitroalkane oxidase | / | 0.445 | |
| 3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.445 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.445 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.445 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.445 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.445 | |
| 1ezv | SMA | Cytochrome b | / | 0.444 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2c6e | HPM | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.444 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.444 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.444 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.444 | |
| 3zux | TCH | Transporter | / | 0.444 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.444 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.443 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.443 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.443 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.443 | |
| 2rr1 | W8R | Genome polyprotein | / | 0.443 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.443 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.443 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.443 | |
| 3hng | 8ST | Vascular endothelial growth factor receptor 1 | 2.7.10.1 | 0.443 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.443 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.443 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.443 | |
| 4u8j | FDA | UDP-galactopyranose mutase | / | 0.443 | |
| 5ag7 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.443 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.442 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.442 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.442 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.442 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.442 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4fv2 | EK5 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.442 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.442 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4u8p | FDA | UDP-galactopyranose mutase | / | 0.442 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.442 | |
| 1fml | RTL | Retinol dehydratase | / | 0.441 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.441 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.441 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.441 | |
| 1zgd | NAP | Chalcone reductase | / | 0.441 | |
| 2apg | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.441 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.441 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.441 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.441 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.441 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.441 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.441 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.441 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.441 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.440 | |
| 3w2c | N15 | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 4gdd | FAD | UDP-galactopyranose mutase | / | 0.440 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.440 | |
| 4lgh | 0JN | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 |