sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1swe | BTN | Streptavidin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1swe | BTN | Streptavidin | / | 1.000 | |
| 1mep | BTN | Streptavidin | / | 0.657 | |
| 1n9m | BTN | Streptavidin | / | 0.618 | |
| 1swn | BTN | Streptavidin | / | 0.593 | |
| 1ndj | BTN | Streptavidin | / | 0.591 | |
| 1nc9 | IMI | Streptavidin | / | 0.585 | |
| 2izh | BTN | Streptavidin | / | 0.585 | |
| 1swp | BTN | Streptavidin | / | 0.582 | |
| 1swp | BTQ | Streptavidin | / | 0.578 | |
| 2zsc | BTN | Tamavidin2 | / | 0.573 | |
| 1swd | BTN | Streptavidin | / | 0.570 | |
| 2rtf | BTN | Streptavidin | / | 0.566 | |
| 1sri | DMB | Streptavidin | / | 0.562 | |
| 4yvb | BTN | Streptavidin | / | 0.560 | |
| 3wyp | BSO | Streptavidin | / | 0.547 | |
| 1stp | BTN | Streptavidin | / | 0.546 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.545 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.532 | |
| 4gda | BTN | Streptavidin | / | 0.531 | |
| 1nqm | BTN | Streptavidin | / | 0.528 | |
| 2rto | IMI | Streptavidin | / | 0.528 | |
| 4bx7 | B4F | Streptavidin | / | 0.528 | |
| 1lcw | SHM | Streptavidin | / | 0.527 | |
| 2izf | BTN | Streptavidin | / | 0.527 | |
| 2rtq | IMI | Streptavidin | / | 0.527 | |
| 4dne | DTB | Streptavidin | / | 0.527 | |
| 1mk5 | BTN | Streptavidin | / | 0.526 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.525 | |
| 2rtg | BTN | Streptavidin | / | 0.525 | |
| 2rtr | IMI | Streptavidin | / | 0.525 | |
| 2y3f | BTN | Streptavidin | / | 0.523 | |
| 2izl | IMI | Streptavidin | / | 0.522 | |
| 4gd9 | BTN | Streptavidin | / | 0.522 | |
| 1srg | MHB | Streptavidin | / | 0.521 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.520 | |
| 1n43 | BTN | Streptavidin | / | 0.519 | |
| 1swt | BTN | Streptavidin | / | 0.518 | |
| 2rte | BTN | Streptavidin | / | 0.517 | |
| 1df8 | BTN | Streptavidin | / | 0.514 | |
| 2avi | BTN | Avidin | / | 0.511 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.511 | |
| 3ry2 | BTN | Streptavidin | / | 0.511 | |
| 2rtd | BTN | Streptavidin | / | 0.510 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.508 | |
| 1rxh | BNI | Streptavidin | / | 0.505 | |
| 1srf | MTB | Streptavidin | / | 0.505 | |
| 2izi | BTN | Streptavidin | / | 0.505 | |
| 3wzn | BTN | Streptavidin | / | 0.505 | |
| 4ggz | BTN | Bll1558 protein | / | 0.505 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.504 | |
| 2izg | BTN | Streptavidin | / | 0.504 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.504 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.504 | |
| 2rtn | IMI | Streptavidin | / | 0.503 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.501 | |
| 4bj8 | BTN | Avidin | / | 0.501 | |
| 1srj | NAB | Streptavidin | / | 0.500 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.499 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.499 | |
| 3rdq | DTB | Streptavidin | / | 0.499 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.496 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.495 | |
| 1srh | MOB | Streptavidin | / | 0.494 | |
| 1luq | BTN | Streptavidin | / | 0.493 | |
| 1swr | BTN | Streptavidin | / | 0.493 | |
| 3vgw | NVZ | Avidin | / | 0.493 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 1avd | BTN | Avidin | / | 0.489 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.489 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 1i9h | BNI | Streptavidin | / | 0.488 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 3vhh | VHH | Avidin | / | 0.486 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 1sre | HAB | Streptavidin | / | 0.481 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.479 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.479 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.478 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.478 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.478 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.477 | |
| 3eks | CY9 | Actin-5C | / | 0.477 | |
| 4kxj | P34 | Nucleoprotein | / | 0.477 | |
| 1c7o | PPG | Hemolysin | / | 0.476 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.476 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.476 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 1lcz | BH7 | Streptavidin | / | 0.475 | |
| 2rtp | IMI | Streptavidin | / | 0.475 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.474 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.474 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.474 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.474 | |
| 2c4i | BTN | Avidin | / | 0.474 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.474 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.474 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.472 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.470 | |
| 2uz2 | BTN | Avd protein | / | 0.470 | |
| 3wyq | BTN | Streptavidin | / | 0.470 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.469 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.468 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.467 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.467 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.467 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.466 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.466 | |
| 4e32 | DWN | Methyltransferase | / | 0.466 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.465 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.465 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.465 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.465 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.465 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.465 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.464 | |
| 2jgs | BTN | Avidin | / | 0.464 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.464 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.464 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.464 | |
| 4phl | PIL | Phosphodiesterase | / | 0.464 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 3ndj | JHZ | Methyltransferase | / | 0.463 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.462 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.462 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.462 | |
| 2rtm | IMI | Streptavidin | / | 0.461 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.461 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3v2u | ATP | Protein GAL3 | / | 0.461 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.460 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.460 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4e2y | JHZ | Methyltransferase | / | 0.460 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.459 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.459 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.459 | |
| 2uyw | BTN | Avd protein | / | 0.459 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.459 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.458 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.457 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.457 | |
| 1vp5 | NAP | Oxidoreductase, aldo/keto reductase family | / | 0.457 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.457 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.457 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.457 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.457 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.457 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.456 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.456 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.456 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.456 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.456 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.456 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.456 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.455 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.455 | |
| 1txz | APR | Probable ADP-ribose 1''-phosphate phosphatase YML087W | 3.1.3.84 | 0.455 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.455 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.455 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.454 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.454 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.454 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.454 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.454 | |
| 4z28 | BTN | Hoefavidin | / | 0.454 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.453 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.453 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.453 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.453 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.452 | |
| 1r2j | FAD | FkbI | / | 0.452 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.452 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.452 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.452 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.452 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.452 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.451 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.451 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.451 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.451 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.451 | |
| 1dtp | APU | Diphtheria toxin | / | 0.450 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.450 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.450 | |
| 2bgs | NDP | Aldose reductase | 1.1.1.21 | 0.450 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.450 | |
| 4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.450 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.449 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.449 | |
| 1yc2 | APR | NAD-dependent protein deacylase 2 | / | 0.449 | |
| 1zdw | FLV | Prenyltransferase | / | 0.449 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.449 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.449 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.449 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.449 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.449 | |
| 4e2z | JHZ | Methyltransferase | / | 0.449 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.449 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.448 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.448 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.448 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.448 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.448 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.448 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.448 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.447 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.447 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.447 | |
| 2mok | FMN | Flavodoxin 1 | / | 0.447 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.447 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.447 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.447 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1m2h | APR | NAD-dependent protein deacylase 1 | / | 0.446 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.446 | |
| 2a5c | 8DA | Avidin | / | 0.446 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.446 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.446 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.446 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.445 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.445 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.445 | |
| 4kwh | NAP | Reductase homolog | / | 0.445 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.444 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.444 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.444 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.444 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.444 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.444 | |
| 4dve | BTN | Biotin transporter BioY | / | 0.444 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.444 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.443 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.443 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.443 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.443 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.443 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.443 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.443 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.443 | |
| 4hlf | 15Z | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4mry | CEI | Obelin | / | 0.443 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.443 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.443 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.442 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.442 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.442 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.442 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.442 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.442 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.442 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4bxk | 1IU | Angiotensin-converting enzyme | 3.2.1 | 0.442 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.442 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.442 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.441 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.441 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.441 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.441 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.441 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.441 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.441 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.441 | |
| 4hlg | 20B | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.441 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.441 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.441 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.440 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1gqy | ACP | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.440 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.440 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.440 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.440 | |
| 1thz | 326 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.440 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.440 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.440 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2pu2 | DK2 | Beta-lactamase | 3.5.2.6 | 0.440 | |
| 2v2v | V12 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.440 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.440 | |
| 3irh | DTP | HD domain protein | / | 0.440 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 4j7h | TRH | PCZA361.3 | / | 0.440 | |
| 4l34 | 1VG | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.440 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.440 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.440 |