scPDB - Distribution of Binding site Similarity values of 1q0b entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1q0b	NAT	Kinesin-like protein KIF11

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1q0b	NAT	Kinesin-like protein KIF11	/	1.000
2ieh	MOY	Kinesin-like protein KIF11	/	0.692
2x7d	EGB	Kinesin-like protein KIF11	/	0.681
3k3b	L31	Kinesin-like protein KIF11	/	0.641
2g1q	N9H	Kinesin-like protein KIF11	/	0.629
1x88	NAT	Kinesin-like protein KIF11	/	0.623
2q2z	MKK	Kinesin-like protein KIF11	/	0.622
2fme	3QC	Kinesin-like protein KIF11	/	0.618
2x7c	KZ9	Kinesin-like protein KIF11	/	0.614
2wog	ZZD	Kinesin-like protein KIF11	/	0.607
3k5e	K5E	Kinesin-like protein KIF11	/	0.607
4bbg	V02	Kinesin-like protein KIF11	/	0.604
3ken	ZZD	Kinesin-like protein KIF11	/	0.603
2x7e	X7E	Kinesin-like protein KIF11	/	0.598
2x2r	X2O	Kinesin-like protein KIF11	/	0.596
4a51	DQ8	Kinesin-like protein KIF11	/	0.569
2gm1	2AZ	Kinesin-like protein KIF11	/	0.562
2xae	2XA	Kinesin-like protein KIF11	/	0.540
4as7	6LX	Kinesin-like protein KIF11	/	0.538
4a5y	G7X	Kinesin-like protein KIF11	/	0.525
2uxh	QUE	HTH-type transcriptional regulator TtgR	/	0.486
4m37	SAH	Protein arginine N-methyltransferase 7	2.1.1	0.483
3gwf	NAP	Cyclohexanone monooxygenase	/	0.480
2bxe	1FL	Serum albumin	/	0.475
1w2x	RCP	Acetyl-CoA carboxylase	/	0.474
4i1n	FOL	Dihydrofolate reductase	1.5.1.3	0.471
1f20	FAD	Nitric oxide synthase, brain	1.14.13.39	0.469
2rh9	IGP	Tryptophan synthase alpha chain	/	0.466
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.466
1rx4	DDF	Dihydrofolate reductase	1.5.1.3	0.465
2w05	FRT	Cyclin-dependent kinase 2	2.7.11.22	0.464
3cin	NAD	Myo-inositol-1-phosphate synthase-related protein	/	0.463
3tki	S25	Serine/threonine-protein kinase Chk1	2.7.11.1	0.462
3h0s	B38	Acetyl-CoA carboxylase	/	0.460
1nvs	UCM	Serine/threonine-protein kinase Chk1	2.7.11.1	0.459
4ysw	NAI	Xanthine dehydrogenase/oxidase	/	0.459
1pq9	44B	Oxysterols receptor LXR-beta	/	0.458
3otb	DGT	Probable tRNA(His) guanylyltransferase	2.7.7.79	0.458
1e8w	QUE	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.457
2cgw	3C3	Serine/threonine-protein kinase Chk1	2.7.11.1	0.457
2piu	DHT	Androgen receptor	/	0.457
4jaz	STL	Peroxisome proliferator-activated receptor gamma	/	0.457
5ack	ATP	3-phosphoinositide-dependent protein kinase 1	2.7.11.1	0.457
3s0o	50Z	Cyclin-dependent kinase 2	2.7.11.22	0.456
3say	OFT	Glycogen synthase kinase-3 beta	2.7.11.26	0.456
4xj3	GTP	Cyclic GMP-AMP synthase	/	0.456
3p2o	NAD	Bifunctional protein FolD	/	0.455
4iyg	1HU	Strictosidine synthase	4.3.3.2	0.454
4l4f	CAM	Camphor 5-monooxygenase	1.14.15.1	0.454
4u03	GTP	Cyclic GMP-AMP synthase	/	0.454
4z34	ON7	Lysophosphatidic acid receptor 1	/	0.454
1nvq	UCN	Serine/threonine-protein kinase Chk1	2.7.11.1	0.453
2a1m	CAM	Camphor 5-monooxygenase	1.14.15.1	0.453
2nr4	FMN	Conserved protein	/	0.453
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.453
3u9e	COA	Lmo1369 protein	/	0.453
2yj5	ATP	Copper-transporting ATPase	/	0.452
2yy8	MTA	tRNA (cytidine(56)-2'-O)-methyltransferase	/	0.452
4c9o	CAM	Cytochrome P450	/	0.452
5eku	SAH	Arginine N-methyltransferase, putative	/	0.452
1o76	CAM	Camphor 5-monooxygenase	1.14.15.1	0.451
4yqf	GDP	Septin-9	/	0.451
3mtf	A3F	Activin receptor type-1	2.7.11.30	0.450
4a30	QMI	Glycylpeptide N-tetradecanoyltransferase	/	0.450
4czt	CPS	CBL-interacting serine/threonine-protein kinase 23	2.7.11.1	0.450
5djt	FMN	NPH1-2	/	0.450
1fdw	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.449
3fp0	FP0	15-O-acetyltransferase	/	0.449
4asg	814	ATP-dependent molecular chaperone HSP82	/	0.449
4h3y	SAH	tRNA (guanine-N(1)-)-methyltransferase	/	0.449
2c3k	ABO	Serine/threonine-protein kinase Chk1	2.7.11.1	0.448
4hhd	FMN	Phototropin-1	2.7.11.1	0.448
4l9k	EHF	Serum albumin	/	0.448
4yry	FAD	Glutamate synthase, beta subunit	/	0.448
1fml	RTL	Retinol dehydratase	/	0.447
4ftr	5HK	Serine/threonine-protein kinase Chk1	2.7.11.1	0.447
4iay	ADP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.447
1kfc	IPL	Tryptophan synthase alpha chain	/	0.446
1r35	I58	Nitric oxide synthase, inducible	1.14.13.39	0.446
3a8w	ATP	Protein kinase C iota type	2.7.11.13	0.446
3v49	PK0	Androgen receptor	/	0.446
3zxs	FAD	Deoxyribodipyrimidine photolyase-related protein	/	0.446
4boe	CLR	Japanin	/	0.446
4i13	FOL	Dihydrofolate reductase	1.5.1.3	0.446
4xuh	SFI	Peroxisome proliferator-activated receptor gamma	/	0.446
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.445
4fx9	FAD	Coenzyme A disulfide reductase	1.8.1.14	0.445
1l2t	ATP	Uncharacterized ABC transporter ATP-binding protein MJ0796	/	0.444
2a7r	5GP	GMP reductase 2	/	0.444
2hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.444
2ivp	ATP	tRNA N6-adenosine threonylcarbamoyltransferase	/	0.444
2y9q	ANP	Mitogen-activated protein kinase 1	2.7.11.24	0.444
3e8n	VRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.444
4hyh	1AM	Serine/threonine-protein kinase Chk1	2.7.11.1	0.444
4kky	CAM	Camphor 5-monooxygenase	1.14.15.1	0.444
4ldk	FAD	FAD-linked sulfhydryl oxidase ALR	1.8.3.2	0.444
4rbs	0RV	Metallo-beta-lactamase type 2	/	0.444
1oc1	ASV	Isopenicillin N synthase	1.21.3.1	0.443
1rek	B8L	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.443
2b35	TCL	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.443
2egs	SAH	Diphthine synthase	/	0.443
2pmd	GNP	Translation initiation factor 2 subunit gamma	/	0.443
2uxp	CLM	HTH-type transcriptional regulator TtgR	/	0.443
3qtt	ANP	Pantothenate synthetase	/	0.443
4w9w	YDJ	BMP-2-inducible protein kinase	2.7.11.1	0.443
1dhr	NAD	Dihydropteridine reductase	1.5.1.34	0.442
1fm4	DXC	Major pollen allergen Bet v 1-L	/	0.442
1svl	ADP	Large T antigen	3.6.4	0.442
2brn	DF1	Serine/threonine-protein kinase Chk1	2.7.11.1	0.442
2ojg	19A	Mitogen-activated protein kinase 1	2.7.11.24	0.442
3e68	AT6	Nitric oxide synthase, inducible	1.14.13.39	0.442
3eah	327	Nitric oxide synthase, endothelial	1.14.13.39	0.442
3jus	BCD	Lanosterol 14-alpha demethylase	1.14.13.70	0.442
3lzv	017	Gag-Pol polyprotein	3.4.23.16	0.442
4iwo	1H4	Serine/threonine-protein kinase TBK1	2.7.11.1	0.442
1h1p	CMG	Cyclin-dependent kinase 2	2.7.11.22	0.441
1p91	SAM	23S rRNA (guanine(745)-N(1))-methyltransferase	/	0.441
1sui	SAH	Caffeoyl-CoA O-methyltransferase	2.1.1.104	0.441
2egb	SAH	Diphthine synthase	/	0.441
2iyg	FMN	AppA, antirepressor of ppsR, sensor of blue light	/	0.441
2xvv	9DN	Serum albumin	/	0.441
3n65	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.441
3qx4	X4B	Cyclin-dependent kinase 2	2.7.11.22	0.441
1q6y	COA	Formyl-CoA:oxalate CoA-transferase	/	0.440
1snu	STU	Tyrosine-protein kinase ITK/TSK	2.7.10.2	0.440
2ieb	ZID	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.440
2itp	AEE	Epidermal growth factor receptor	2.7.10.1	0.440
2ptf	FMN	Uncharacterized protein MTH_863	/	0.440
3ddp	RC8	Cyclin-dependent kinase 2	2.7.11.22	0.440
3dga	NDP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.440
3is2	FAD	Vivid PAS protein VVD	/	0.440
3rjc	06Z	Cyclin-dependent kinase 2	2.7.11.22	0.440
3smk	CW7	14-3-3 protein sigma	/	0.440
4cdm	FAD	Deoxyribodipyrimidine photolyase	/	0.440
4k9n	TZD	Benzoylformate decarboxylase	4.1.1.7	0.440
4l4e	CAM	Camphor 5-monooxygenase	1.14.15.1	0.440
4u0m	GTP	Cyclic GMP-AMP synthase	/	0.440