Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3sfe FAD Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3sfe FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.458
3sfd FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.370
3aeb FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.228
4yxd FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.211
4ytn FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.143
5c2t FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.116
3ae4 FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.057
5c3j FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial / 1.052
1kf6 FADFumarate reductase flavoprotein subunit 1.3.5.4 0.924
1knp FADL-aspartate oxidase 1.4.3.16 0.922
4kx6 FADFumarate reductase flavoprotein subunit 1.3.5.4 0.916
1knr FADL-aspartate oxidase 1.4.3.16 0.879
4yjd FADD-amino-acid oxidase 1.4.3.3 0.818
3cuk FADD-amino-acid oxidase 1.4.3.3 0.811
1c0l FADD-amino-acid oxidase 1.4.3.3 0.805
1d4c FADFumarate reductase flavoprotein subunit 1.3.5.4 0.803
1kif FADD-amino-acid oxidase 1.4.3.3 0.802
1c0k FADD-amino-acid oxidase 1.4.3.3 0.800
1ryi FADGlycine oxidase 1.4.3.19 0.797
1d4d FADFumarate reductase flavoprotein subunit 1.3.5.4 0.786
2du8 FADD-amino-acid oxidase 1.4.3.3 0.772
1ng4 FADGlycine oxidase 1.4.3.19 0.750
4opc FDAConserved Archaeal protein / 0.748
2c4c FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.745
4jn9 FADDepH / 0.740
3znp FADD-amino-acid oxidase 1.4.3.3 0.739
4c3y FAD3-ketosteroid dehydrogenase / 0.739
1ng3 FADGlycine oxidase 1.4.3.19 0.736
4opi FDAConserved Archaeal protein / 0.735
3atr FDAConserved Archaeal protein / 0.734
4opd FDAConserved Archaeal protein / 0.733
1tde FADThioredoxin reductase 1.8.1.9 0.730
4nwz FADFAD-dependent pyridine nucleotide-disulfide oxidoreductase / 0.730
1tdf FADThioredoxin reductase 1.8.1.9 0.729
4cnj FADL-amino acid oxidase / 0.727
1trb FADThioredoxin reductase 1.8.1.9 0.726
5ez7 FADProbable FAD-dependent oxidoreductase PA4991 / 0.726
4x9n FADUncharacterized protein MG039 homolog / 0.725
4o5q FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.718
4opg FDAConserved Archaeal protein / 0.718
2gmh FADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial 1.5.5.1 0.717
1ve9 FADD-amino-acid oxidase 1.4.3.3 0.716
4opt FDAConserved Archaeal protein / 0.716
4opl FDAConserved Archaeal protein / 0.715
3t37 FADPyridoxine 4-oxidase / 0.714
4c3x FAD3-ketosteroid dehydrogenase / 0.712
1gth FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.710
4opu FDAConserved Archaeal protein / 0.709
2dw4 FADLysine-specific histone demethylase 1A 1 0.708
3hjk FADVivid PAS protein VVD / 0.708
3axb FADPutative oxidoreductase / 0.707
3gsi FADDimethylglycine oxidase 1.5.3.10 0.707
3pvc FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.706
3atq FDAConserved Archaeal protein / 0.704
1gal FADGlucose oxidase 1.1.3.4 0.703
3ntd FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.703
4gut FADLysine-specific histone demethylase 1B 1 0.701
3bg7 FADPyranose 2-oxidase / 0.700
4em4 FADCoenzyme A disulfide reductase / 0.700
1xdi FADNAD(P)H dehydrogenase (quinone) / 0.699
3cge FADCoenzyme A disulfide reductase / 0.699
2c3c FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.698
4wct FADFructosyl amine:oxygen oxidoreductase / 0.697
2rab FADGlutathione amide reductase / 0.696
4gdp FADPolyamine oxidase FMS1 / 0.695
3cty FADProbable thioredoxin reductase / 0.694
4xwz FADFructosyl amine:oxygen oxidoreductase / 0.694
4gcm FADThioredoxin reductase 1.8.1.9 0.693
4guu FA9Lysine-specific histone demethylase 1B 1 0.693
1qo8 FADFumarate reductase flavoprotein subunit / 0.692
1grh FADGlutathione reductase, mitochondrial 1.8.1.7 0.691
1rsg FADPolyamine oxidase FMS1 / 0.690
4o5u FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.689
2gqf FADUncharacterized protein HI_0933 / 0.688
2whd FADThioredoxin reductase / 0.688
3ad9 FADSubunit beta of sarcosine oxidase / 0.688
2ign FADPyranose 2-oxidase / 0.686
1fl2 FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.684
3cox FADCholesterol oxidase 1.1.3.6 0.684
4u2t FADCholesterol oxidase 1.1.3.6 0.684
5i39 FADL-amino acid deaminase / 0.684
3sgl FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.682
2iw5 FADLysine-specific histone demethylase 1A 1 0.681
1zy8 FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.680
2z6c FMNPhototropin-1 2.7.11.1 0.680
3nyc FADFAD-dependent catabolic D-arginine dehydrogenase DauA / 0.679
4x9m FADUncharacterized protein MG039 homolog / 0.679
1h7w FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.678
2ok7 FADFerredoxin--NADP reductase, apicoplast / 0.678
4qi5 FADCellobiose dehydrogenase / 0.678
4ysh FADGlycine oxidase / 0.678
1gte FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.677
3k7m FAD6-hydroxy-L-nicotine oxidase / 0.677
4xbf FADLysine-specific histone demethylase 1A 1 0.677
5eb5 FAD(R)-mandelonitrile lyase 1 4.1.2.10 0.677
4cy8 FDA2-hydroxybiphenyl-3-monooxygenase / 0.676
4mok FADPyranose 2-oxidase / 0.676
4udr FAD5-(hydroxymethyl)furfural oxidase / 0.676
1h83 FADPolyamine oxidase 1.5.3.14 0.675
3cgc FADCoenzyme A disulfide reductase / 0.675
4em3 FADCoenzyme A disulfide reductase / 0.675
4emw FADCoenzyme A disulfide reductase / 0.675
3sm8 FNKFAD-dependent catabolic D-arginine dehydrogenase DauA / 0.674
2pd8 FADVivid PAS protein VVD / 0.673
3hji FADVivid PAS protein VVD / 0.673
3vqr FADPutative oxidoreductase / 0.673
4ees FMNPhototropin-2 2.7.11.1 0.673
4qi4 FADCellobiose dehydrogenase / 0.673
4udq FAD5-(hydroxymethyl)furfural oxidase / 0.672
4up3 FADThioredoxin reductase / 0.672
4wuj FMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy / 0.672
1get FADGlutathione reductase 1.8.1.7 0.671
1zmc FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.671
2uxx FAJLysine-specific histone demethylase 1A 1 0.671
2y48 FADLysine-specific histone demethylase 1A 1 0.671
4eep FMNPhototropin-2 2.7.11.1 0.671
2b9x FADPutative aminooxidase / 0.670
2gew FADCholesterol oxidase 1.1.3.6 0.670
3oc4 FADOxidoreductase, pyridine nucleotide-disulfide family / 0.670
4fwe FADLysine-specific histone demethylase 1B 1 0.670
1ju2 FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.669
1siq FADGlutaryl-CoA dehydrogenase, mitochondrial 1.3.8.6 0.669
2b9w FADPutative aminooxidase / 0.668
3cn8 FADPolyamine oxidase FMS1 / 0.668
2gv8 FADThiol-specific monooxygenase 1.14.13 0.667
3gwd FADCyclohexanone monooxygenase / 0.667
3mkh FADNitroalkane oxidase / 0.667
4nm9 FADBifunctional protein PutA / 0.667
3m13 FADMonomeric sarcosine oxidase 1.5.3.1 0.666
4eer FMNPhototropin-2 2.7.11.1 0.666
4eqx FADCoenzyme A disulfide reductase / 0.666
4gus FADLysine-specific histone demethylase 1B 1 0.666
4eet FMNPhototropin-2 2.7.11.1 0.665
2e1m FADL-glutamate oxidase / 0.664
3fbs FADOxidoreductase / 0.664
3lov FADProtoporphyrinogen oxidase / 0.664
4hsu FADLysine-specific histone demethylase 1B 1 0.664
4jdr FADDihydrolipoyl dehydrogenase 1.8.1.4 0.664
4lii FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.664
1h81 FADPolyamine oxidase 1.5.3.14 0.663
2iyg FMNAppA, antirepressor of ppsR, sensor of blue light / 0.663
3cnd FADPolyamine oxidase FMS1 / 0.663
4wf0 FMNNPH1-1 / 0.663
1sez FADProtoporphyrinogen oxidase, mitochondrial 1.3.3.4 0.662
2a87 FADThioredoxin reductase 1.8.1.9 0.662
3jqr FADFerredoxin--NADP reductase, apicoplast / 0.662
4r38 RBFBlue-light-activated histidine kinase 2 2.7.13.3 0.662
2j3n FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.661
3d72 FADVivid PAS protein VVD / 0.661
4gur FADLysine-specific histone demethylase 1B 1 0.661
5j60 FADThioredoxin reductase / 0.661
1kyv RBF6,7-dimethyl-8-ribityllumazine synthase 2.5.1.78 0.660
2h94 FADLysine-specific histone demethylase 1A 1 0.660
3nt6 FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.660
1yrx FMNAppA protein / 0.659
2bab FADPutative aminooxidase / 0.659
3uoz FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.659
2ar8 FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.658
3cnt FADPolyamine oxidase FMS1 / 0.658
3dme FADPutative conserved exported protein / 0.658
4at0 FADPossible succinate dehydrogenase / 0.658
4jnq FDAThioredoxin reductase / 0.658
1yy5 FADPolyamine oxidase FMS1 / 0.657
4m52 FADDihydrolipoyl dehydrogenase 1.8.1.4 0.657
4r3a RBFBlue-light-activated histidine kinase 2 2.7.13.3 0.657
4ykf FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.657
1m6i FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.656
2ok8 FADFerredoxin--NADP reductase, apicoplast / 0.656
2z6d FMNPhototropin-2 2.7.11.1 0.656
3dh9 FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.656
3djj FADGlutathione reductase, mitochondrial 1.8.1.7 0.656
3k4c FADPyranose 2-oxidase / 0.656
4ccq FADThioredoxin reductase / 0.656
1amo FADNADPH--cytochrome P450 reductase / 0.655
2b9y FADPutative aminooxidase / 0.655
2pdt FADVivid PAS protein VVD / 0.655
3cnj FADCholesterol oxidase 1.1.3.6 0.655
3gdp FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.655
3kkj FADRenalase / 0.655
2rgo FADAlpha-Glycerophosphate Oxidase / 0.654
2vvl FADMonoamine oxidase N 1.4.3.4 0.654
3is2 FADVivid PAS protein VVD / 0.654
2bac FADPutative aminooxidase / 0.653
2q0k FADThioredoxin reductase 1.8.1.9 0.653
3up5 FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.653
4hh0 FMNAppA protein / 0.653
1gpe FADGlucose oxidase 1.1.3.4 0.652
2byc FMNBlue-light receptor of the BLUF-family / 0.652
3if9 FADGlycine oxidase 1.4.3.19 0.652
2hfo FMNActivator of photopigment and puc expression / 0.651
4ntc FADThioredoxin reductase gliT / 0.651
1ebd FADDihydrolipoyl dehydrogenase 1.8.1.4 0.650
1mok FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.650
1tdo FADL-amino-acid oxidase 1.4.3.2 0.650
1z6l FADPolyamine oxidase FMS1 / 0.650
2cdu FADNADH oxidase / 0.650
3hgo FMN12-oxophytodienoate reductase 3 1.3.1.42 0.650
3qvp FADGlucose oxidase 1.1.3.4 0.650