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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2r64740Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2r64740Cyclin-dependent kinase 22.7.11.221.000
3s2pPMUCyclin-dependent kinase 22.7.11.220.626
3qwjX6ACyclin-dependent kinase 22.7.11.220.570
2uznC96Cyclin-dependent kinase 22.7.11.220.569
2w05FRTCyclin-dependent kinase 22.7.11.220.568
3r9dX6BCyclin-dependent kinase 22.7.11.220.563
3qtzX42Cyclin-dependent kinase 22.7.11.220.557
1ckpPVBCyclin-dependent kinase 22.7.11.220.555
1gih1PUCyclin-dependent kinase 22.7.11.220.555
1v1k3FPCyclin-dependent kinase 22.7.11.220.551
3lfqA28Cyclin-dependent kinase 22.7.11.220.550
2duv371Cyclin-dependent kinase 22.7.11.220.545
3qxoX65Cyclin-dependent kinase 22.7.11.220.545
4erwSTUCyclin-dependent kinase 22.7.11.220.540
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.538
3le62BZCyclin-dependent kinase 22.7.11.220.534
1oiqHDUCyclin-dependent kinase 22.7.11.220.533
2w06FRVCyclin-dependent kinase 22.7.11.220.533
4fkpLS5Cyclin-dependent kinase 22.7.11.220.530
2j9mPY8Cyclin-dependent kinase 22.7.11.220.529
1ke5LS1Cyclin-dependent kinase 22.7.11.220.528
1oitHDTCyclin-dependent kinase 22.7.11.220.528
4lyn1YGCyclin-dependent kinase 22.7.11.220.527
2btrU73Cyclin-dependent kinase 22.7.11.220.525
1ke6LS2Cyclin-dependent kinase 22.7.11.220.524
4fkq42KCyclin-dependent kinase 22.7.11.220.524
1ke7LS3Cyclin-dependent kinase 22.7.11.220.523
3r7iX9ICyclin-dependent kinase 22.7.11.220.523
2btsU32Cyclin-dependent kinase 22.7.11.220.522
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.521
4ek610KCyclin-dependent kinase 22.7.11.220.521
1ke9LS5Cyclin-dependent kinase 22.7.11.220.520
2b52D42Cyclin-dependent kinase 22.7.11.220.520
4fkt48KCyclin-dependent kinase 22.7.11.220.520
2w1hL0FCyclin-dependent kinase 22.7.11.220.519
3lfsA07Cyclin-dependent kinase 22.7.11.220.518
4ez30S0Cyclin-dependent kinase 22.7.11.220.518
4fkj11KCyclin-dependent kinase 22.7.11.220.518
3lfnA27Cyclin-dependent kinase 22.7.11.220.517
3roy22ZCyclin-dependent kinase 22.7.11.220.516
4fki09KCyclin-dependent kinase 22.7.11.220.515
3sqq99ZCyclin-dependent kinase 22.7.11.220.514
2vtrLZBCyclin-dependent kinase 22.7.11.220.512
3r1sX73Cyclin-dependent kinase 22.7.11.220.512
3r73X87Cyclin-dependent kinase 22.7.11.220.511
3iggEFQCyclin-dependent kinase 22.7.11.220.510
4fkr45KCyclin-dependent kinase 22.7.11.220.509
3rmf20ZCyclin-dependent kinase 22.7.11.220.508
1vyzN5BCyclin-dependent kinase 22.7.11.220.507
3r7yZ04Cyclin-dependent kinase 22.7.11.220.507
1v0pPVBCell division control protein 2 homolog2.7.11.220.505
1oguST8Cyclin-dependent kinase 22.7.11.220.504
3qzgX67Cyclin-dependent kinase 22.7.11.220.504
3r7vZ02Cyclin-dependent kinase 22.7.11.220.504
1aq1STUCyclin-dependent kinase 22.7.11.220.503
3ti1B49Cyclin-dependent kinase 22.7.11.220.503
3r1yX76Cyclin-dependent kinase 22.7.11.220.502
1di8DTQCyclin-dependent kinase 22.7.11.220.501
2bheBRYCyclin-dependent kinase 22.7.11.220.500
3ddpRC8Cyclin-dependent kinase 22.7.11.220.498
3qzhX69Cyclin-dependent kinase 22.7.11.220.498
3r71X86Cyclin-dependent kinase 22.7.11.220.498
2r3lSCWCyclin-dependent kinase 22.7.11.220.497
1pxmCK5Cyclin-dependent kinase 22.7.11.220.496
3qqfX07Cyclin-dependent kinase 22.7.11.220.495
3qwkX62Cyclin-dependent kinase 22.7.11.220.495
3ezvEZVCyclin-dependent kinase 22.7.11.220.494
3rm719ZCyclin-dependent kinase 22.7.11.220.494
2fvdLIACyclin-dependent kinase 22.7.11.220.493
1vyw292Cyclin-dependent kinase 22.7.11.220.492
3rni21ZCyclin-dependent kinase 22.7.11.220.492
3rpv26ZCyclin-dependent kinase 22.7.11.220.490
3ezrEZRCyclin-dependent kinase 22.7.11.220.489
3qxpX64Cyclin-dependent kinase 22.7.11.220.489
4fkv61KCyclin-dependent kinase 22.7.11.220.489
3r7uX96Cyclin-dependent kinase 22.7.11.220.488
3ral04ZCyclin-dependent kinase 22.7.11.220.488
1h1r6CPCyclin-dependent kinase 22.7.11.220.486
3r1qX75Cyclin-dependent kinase 22.7.11.220.486
1oi9N20Cyclin-dependent kinase 22.7.11.220.485
2a4lRRCCyclin-dependent kinase 22.7.11.220.485
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.485
1ke8LS4Cyclin-dependent kinase 22.7.11.220.484
4acm7YGCyclin-dependent kinase 22.7.11.220.483
2iw94SPCyclin-dependent kinase 22.7.11.220.482
3r28XA0Cyclin-dependent kinase 22.7.11.220.482
4bgh3I6Cyclin-dependent kinase 22.7.11.220.482
3rpy27ZCyclin-dependent kinase 22.7.11.220.481
1h1s4SPCyclin-dependent kinase 22.7.11.220.480
1urwI1PCyclin-dependent kinase 22.7.11.220.480
2r3iSCFCyclin-dependent kinase 22.7.11.220.480
4bcpT3CCyclin-dependent kinase 22.7.11.220.479
3unk0BYCyclin-dependent kinase 22.7.11.220.478
1unlRRCCyclin-dependent-like kinase 52.7.11.10.477
2b55D31Cyclin-dependent kinase 22.7.11.220.477
3r8zZ63Cyclin-dependent kinase 22.7.11.220.477
3uli1N3Cyclin-dependent kinase 22.7.11.220.477
1fvt106Cyclin-dependent kinase 22.7.11.220.475
2ds11CDCyclin-dependent kinase 22.7.11.220.475
1oiyN41Cyclin-dependent kinase 22.7.11.220.474
1p2a5BNCyclin-dependent kinase 22.7.11.220.474
2xmyCDKCyclin-dependent kinase 22.7.11.220.474
3rak03ZCyclin-dependent kinase 22.7.11.220.474
1b39ATPCyclin-dependent kinase 22.7.11.220.472
3r9hZ67Cyclin-dependent kinase 22.7.11.220.472
1h0w207Cyclin-dependent kinase 22.7.11.220.469
3r9oZ71Cyclin-dependent kinase 22.7.11.220.465
3s0o50ZCyclin-dependent kinase 22.7.11.220.465
1ykr628Cyclin-dependent kinase 22.7.11.220.464
2vthLZ2Cyclin-dependent kinase 22.7.11.220.464
3ddqRRCCyclin-dependent kinase 22.7.11.220.463
4eor4SPCyclin-dependent kinase 22.7.11.220.463
1pxpCK8Cyclin-dependent kinase 22.7.11.220.462
1w0xOLOCyclin-dependent kinase 22.7.11.220.462
2iw84SPCyclin-dependent kinase 22.7.11.220.462
3sw418KCyclin-dependent kinase 22.7.11.220.462
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.461
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.459
3qx2X63Cyclin-dependent kinase 22.7.11.220.459
2c5nCK8Cyclin-dependent kinase 22.7.11.220.458
3nup3NUCyclin-dependent kinase 62.7.11.220.458
4fko20KCyclin-dependent kinase 22.7.11.220.458
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.457
1gii1PUCyclin-dependent kinase 22.7.11.220.456
3r7eX88Cyclin-dependent kinase 22.7.11.220.455
3qtuX44Cyclin-dependent kinase 22.7.11.220.453
3raiX85Cyclin-dependent kinase 22.7.11.220.452
2b53D23Cyclin-dependent kinase 22.7.11.220.451
2bhhRYUCyclin-dependent kinase 22.7.11.220.451
2vv9IM9Cyclin-dependent kinase 22.7.11.220.451
4fkw62KCyclin-dependent kinase 22.7.11.220.451
1b38ATPCyclin-dependent kinase 22.7.11.220.450
1pxkCK3Cyclin-dependent kinase 22.7.11.220.450
1w8cN69Cyclin-dependent kinase 22.7.11.220.450
3rk507ZCyclin-dependent kinase 22.7.11.220.450
4fklCK2Cyclin-dependent kinase 22.7.11.220.450
3ig7EFPCyclin-dependent kinase 22.7.11.220.449
3qqhX0ACyclin-dependent kinase 22.7.11.220.449
2r3gSC9Cyclin-dependent kinase 22.7.11.220.448
3qruX19Cyclin-dependent kinase 22.7.11.220.448
2c6iDT1Cyclin-dependent kinase 22.7.11.220.447
2r3jSCJCyclin-dependent kinase 22.7.11.220.447
1r78FMDCyclin-dependent kinase 22.7.11.220.446
1h0vUN4Cyclin-dependent kinase 22.7.11.220.445
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.445
4ez50RSCyclin-dependent kinase 62.7.11.220.445
1pyePM1Cyclin-dependent kinase 22.7.11.220.444
3qtxX43Cyclin-dependent kinase 22.7.11.220.444
4eok4SPCyclin-dependent kinase 22.7.11.220.444
1dm2HMDCyclin-dependent kinase 22.7.11.220.443
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.443
2c6tDT5Cyclin-dependent kinase 22.7.11.220.442
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.442
1h1q2A6Cyclin-dependent kinase 22.7.11.220.441
3qx4X4BCyclin-dependent kinase 22.7.11.220.441
2vtsLZCCyclin-dependent kinase 22.7.11.220.440
4eon1ROCyclin-dependent kinase 22.7.11.220.440