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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2r3p3SCCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2r3p3SCCyclin-dependent kinase 22.7.11.221.000
2r3mSCXCyclin-dependent kinase 22.7.11.220.699
4fkt48KCyclin-dependent kinase 22.7.11.220.659
2c6iDT1Cyclin-dependent kinase 22.7.11.220.652
2r3fSC8Cyclin-dependent kinase 22.7.11.220.642
2r3iSCFCyclin-dependent kinase 22.7.11.220.632
2btrU73Cyclin-dependent kinase 22.7.11.220.628
2r3q5SCCyclin-dependent kinase 22.7.11.220.626
2r3jSCJCyclin-dependent kinase 22.7.11.220.623
3r7yZ04Cyclin-dependent kinase 22.7.11.220.606
1ykr628Cyclin-dependent kinase 22.7.11.220.603
3r1yX76Cyclin-dependent kinase 22.7.11.220.595
2r3kSCQCyclin-dependent kinase 22.7.11.220.588
4ek816KCyclin-dependent kinase 22.7.11.220.582
3lfsA07Cyclin-dependent kinase 22.7.11.220.580
4ek610KCyclin-dependent kinase 22.7.11.220.577
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.575
3iggEFQCyclin-dependent kinase 22.7.11.220.574
2a0cCK9Cyclin-dependent kinase 22.7.11.220.572
2r3r6SCCyclin-dependent kinase 22.7.11.220.566
2c6o4SPCyclin-dependent kinase 22.7.11.220.565
3qxoX65Cyclin-dependent kinase 22.7.11.220.565
1b39ATPCyclin-dependent kinase 22.7.11.220.562
3fz1B98Cyclin-dependent kinase 22.7.11.220.562
2r3o2SCCyclin-dependent kinase 22.7.11.220.556
3lfqA28Cyclin-dependent kinase 22.7.11.220.556
2j9mPY8Cyclin-dependent kinase 22.7.11.220.554
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.548
3r7uX96Cyclin-dependent kinase 22.7.11.220.548
1w0xOLOCyclin-dependent kinase 22.7.11.220.546
2r3lSCWCyclin-dependent kinase 22.7.11.220.544
4fkpLS5Cyclin-dependent kinase 22.7.11.220.544
4fkq42KCyclin-dependent kinase 22.7.11.220.544
3rpv26ZCyclin-dependent kinase 22.7.11.220.542
4fklCK2Cyclin-dependent kinase 22.7.11.220.542
3r8lZ30Cyclin-dependent kinase 22.7.11.220.541
3r7vZ02Cyclin-dependent kinase 22.7.11.220.540
3rm719ZCyclin-dependent kinase 22.7.11.220.534
3s2pPMUCyclin-dependent kinase 22.7.11.220.532
2uznC96Cyclin-dependent kinase 22.7.11.220.531
3ezvEZVCyclin-dependent kinase 22.7.11.220.531
1ke5LS1Cyclin-dependent kinase 22.7.11.220.530
1oitHDTCyclin-dependent kinase 22.7.11.220.530
3raiX85Cyclin-dependent kinase 22.7.11.220.528
1gii1PUCyclin-dependent kinase 22.7.11.220.525
4fki09KCyclin-dependent kinase 22.7.11.220.525
1pxoCK7Cyclin-dependent kinase 22.7.11.220.524
1pxmCK5Cyclin-dependent kinase 22.7.11.220.523
3r83Z14Cyclin-dependent kinase 22.7.11.220.523
2uzoC62Cyclin-dependent kinase 22.7.11.220.521
3ral04ZCyclin-dependent kinase 22.7.11.220.521
3ezrEZRCyclin-dependent kinase 22.7.11.220.520
3pj8404Cyclin-dependent kinase 22.7.11.220.520
2c6lDT4Cyclin-dependent kinase 22.7.11.220.518
3r7iX9ICyclin-dependent kinase 22.7.11.220.517
3qxpX64Cyclin-dependent kinase 22.7.11.220.515
4fkg4CKCyclin-dependent kinase 22.7.11.220.515
1p2a5BNCyclin-dependent kinase 22.7.11.220.513
3rni21ZCyclin-dependent kinase 22.7.11.220.513
3qzgX67Cyclin-dependent kinase 22.7.11.220.511
4bgh3I6Cyclin-dependent kinase 22.7.11.220.511
2vthLZ2Cyclin-dependent kinase 22.7.11.220.510
1vyzN5BCyclin-dependent kinase 22.7.11.220.509
2r64740Cyclin-dependent kinase 22.7.11.220.508
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.508
2c69CT8Cyclin-dependent kinase 22.7.11.220.507
3s1h56ZCyclin-dependent kinase 22.7.11.220.507
1pxpCK8Cyclin-dependent kinase 22.7.11.220.506
2w06FRVCyclin-dependent kinase 22.7.11.220.506
3lfnA27Cyclin-dependent kinase 22.7.11.220.505
3rak03ZCyclin-dependent kinase 22.7.11.220.505
3sw719KCyclin-dependent kinase 22.7.11.220.503
3ig7EFPCyclin-dependent kinase 22.7.11.220.502
3qruX19Cyclin-dependent kinase 22.7.11.220.502
3roy22ZCyclin-dependent kinase 22.7.11.220.502
1y8yCT7Cyclin-dependent kinase 22.7.11.220.501
3rjc06ZCyclin-dependent kinase 22.7.11.220.501
2btsU32Cyclin-dependent kinase 22.7.11.220.499
2fvdLIACyclin-dependent kinase 22.7.11.220.499
2r3gSC9Cyclin-dependent kinase 22.7.11.220.499
3qqhX0ACyclin-dependent kinase 22.7.11.220.499
2a4lRRCCyclin-dependent kinase 22.7.11.220.498
3r9nZ68Cyclin-dependent kinase 22.7.11.220.498
2exmZIPCyclin-dependent kinase 22.7.11.220.497
3pxyJWSCyclin-dependent kinase 22.7.11.220.497
3qwjX6ACyclin-dependent kinase 22.7.11.220.496
4fks46KCyclin-dependent kinase 22.7.11.220.496
1w8cN69Cyclin-dependent kinase 22.7.11.220.495
3r73X87Cyclin-dependent kinase 22.7.11.220.495
1fvt106Cyclin-dependent kinase 22.7.11.220.494
3r28XA0Cyclin-dependent kinase 22.7.11.220.494
3rm618ZCyclin-dependent kinase 22.7.11.220.494
3rahO1ZCyclin-dependent kinase 22.7.11.220.493
2w17I19Cyclin-dependent kinase 22.7.11.220.491
2b53D23Cyclin-dependent kinase 22.7.11.220.489
1gih1PUCyclin-dependent kinase 22.7.11.220.488
2c6kDT2Cyclin-dependent kinase 22.7.11.220.487
3r1sX73Cyclin-dependent kinase 22.7.11.220.487
3r9dX6BCyclin-dependent kinase 22.7.11.220.487
3wblPDYCyclin-dependent kinase 22.7.11.220.487
3sqq99ZCyclin-dependent kinase 22.7.11.220.486
1vyw292Cyclin-dependent kinase 22.7.11.220.485
4fkr45KCyclin-dependent kinase 22.7.11.220.485
2xmyCDKCyclin-dependent kinase 22.7.11.220.482
3qqlX03Cyclin-dependent kinase 22.7.11.220.482
2b52D42Cyclin-dependent kinase 22.7.11.220.481
1oiyN41Cyclin-dependent kinase 22.7.11.220.480
1ke6LS2Cyclin-dependent kinase 22.7.11.220.479
3qzfX66Cyclin-dependent kinase 22.7.11.220.479
3qzhX69Cyclin-dependent kinase 22.7.11.220.479
4nj32KDCyclin-dependent kinase 22.7.11.220.479
2vu3LZECyclin-dependent kinase 22.7.11.220.477
3qrtX14Cyclin-dependent kinase 22.7.11.220.477
3r8zZ63Cyclin-dependent kinase 22.7.11.220.476
3rpy27ZCyclin-dependent kinase 22.7.11.220.476
1ke7LS3Cyclin-dependent kinase 22.7.11.220.475
1pxlCK4Cyclin-dependent kinase 22.7.11.220.475
2vttLZDCyclin-dependent kinase 22.7.11.220.475
2wpa889Cyclin-dependent kinase 22.7.11.220.474
3qqfX07Cyclin-dependent kinase 22.7.11.220.473
3qtxX43Cyclin-dependent kinase 22.7.11.220.473
1v1k3FPCyclin-dependent kinase 22.7.11.220.472
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.472
1h0vUN4Cyclin-dependent kinase 22.7.11.220.471
3qtrX36Cyclin-dependent kinase 22.7.11.220.471
1oiqHDUCyclin-dependent kinase 22.7.11.220.469
2iw84SPCyclin-dependent kinase 22.7.11.220.469
3qtsX46Cyclin-dependent kinase 22.7.11.220.469
4fkj11KCyclin-dependent kinase 22.7.11.220.469
1g5sI17Cyclin-dependent kinase 22.7.11.220.468
4kd11QKCyclin-dependent kinase 22.7.11.220.468
3r9hZ67Cyclin-dependent kinase 22.7.11.220.467
3qtuX44Cyclin-dependent kinase 22.7.11.220.466
3r8pZ46Cyclin-dependent kinase 22.7.11.220.466
3rk909ZCyclin-dependent kinase 22.7.11.220.466
4acm7YGCyclin-dependent kinase 22.7.11.220.466
4ez30S0Cyclin-dependent kinase 22.7.11.220.464
1h0w207Cyclin-dependent kinase 22.7.11.220.462
3r6xX84Cyclin-dependent kinase 22.7.11.220.462
3qqkX02Cyclin-dependent kinase 22.7.11.220.461
2b54D05Cyclin-dependent kinase 22.7.11.220.460
3rk708ZCyclin-dependent kinase 22.7.11.220.460
4fx360KCyclin-dependent kinase 22.7.11.220.460
2c6mDT5Cyclin-dependent kinase 22.7.11.220.459
1urwI1PCyclin-dependent kinase 22.7.11.220.458
2i40BLZCyclin-dependent kinase 22.7.11.220.458
3r1qX75Cyclin-dependent kinase 22.7.11.220.458
1finATPCyclin-dependent kinase 22.7.11.220.457
1oguST8Cyclin-dependent kinase 22.7.11.220.457
1oi9N20Cyclin-dependent kinase 22.7.11.220.457
1oirHDYCyclin-dependent kinase 22.7.11.220.457
3qtzX42Cyclin-dependent kinase 22.7.11.220.457
1fvv107Cyclin-dependent kinase 22.7.11.220.455
4fko20KCyclin-dependent kinase 22.7.11.220.455
1ckpPVBCyclin-dependent kinase 22.7.11.220.454
4eok4SPCyclin-dependent kinase 22.7.11.220.454
1dm2HMDCyclin-dependent kinase 22.7.11.220.453
3my5RFZCyclin-dependent kinase 22.7.11.220.452
3tnwF18Cyclin-dependent kinase 22.7.11.220.452
1b38ATPCyclin-dependent kinase 22.7.11.220.451
1pyePM1Cyclin-dependent kinase 22.7.11.220.451
3unk0BYCyclin-dependent kinase 22.7.11.220.451
4lyn1YGCyclin-dependent kinase 22.7.11.220.451
1pxkCK3Cyclin-dependent kinase 22.7.11.220.449
2w1hL0FCyclin-dependent kinase 22.7.11.220.449
3ddpRC8Cyclin-dependent kinase 22.7.11.220.449
1ke9LS5Cyclin-dependent kinase 22.7.11.220.448
1y91CT9Cyclin-dependent kinase 22.7.11.220.448
3qu0X40Cyclin-dependent kinase 22.7.11.220.448
3ti1B49Cyclin-dependent kinase 22.7.11.220.448
4fkw62KCyclin-dependent kinase 22.7.11.220.448
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.447
3qx2X63Cyclin-dependent kinase 22.7.11.220.447
3rk507ZCyclin-dependent kinase 22.7.11.220.447
3sw418KCyclin-dependent kinase 22.7.11.220.447
3qqgX06Cyclin-dependent kinase 22.7.11.220.446
1ke8LS4Cyclin-dependent kinase 22.7.11.220.445
3ddqRRCCyclin-dependent kinase 22.7.11.220.445
3qziX72Cyclin-dependent kinase 22.7.11.220.445
3r8vZ62Cyclin-dependent kinase 22.7.11.220.445
4eol1ROCyclin-dependent kinase 22.7.11.220.445
4fkv61KCyclin-dependent kinase 22.7.11.220.445
2wxvWXVCyclin-dependent kinase 22.7.11.220.444
3r8uZ31Cyclin-dependent kinase 22.7.11.220.442
1h1s4SPCyclin-dependent kinase 22.7.11.220.441
2c6tDT5Cyclin-dependent kinase 22.7.11.220.441
1unlRRCCyclin-dependent-like kinase 52.7.11.10.440
2c5yMTWCyclin-dependent kinase 22.7.11.220.440
3rzb02ZCyclin-dependent kinase 22.7.11.220.440
4erwSTUCyclin-dependent kinase 22.7.11.220.440