sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 1.000 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 1.000 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.494 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.486 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.485 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.484 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.482 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.481 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.480 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.479 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.479 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.479 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.474 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.474 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.474 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.473 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.472 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.471 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.471 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.471 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.470 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.470 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.469 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.468 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.468 | |
| 2p3b | 3TL | V-1 protease | / | 0.468 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.468 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.467 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.466 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.466 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.465 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.465 | |
| 3ii4 | 3II | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.465 | |
| 3pwm | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 3s43 | 478 | Protease | / | 0.464 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.464 | |
| 3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.464 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.464 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.462 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.462 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.461 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.461 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.460 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.460 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.459 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.459 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.459 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.458 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.458 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4a4q | UX9 | Pol protein | / | 0.458 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.458 | |
| 1ivq | 0PX | Gag-Pol polyprotein | / | 0.457 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3el9 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.457 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.456 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.456 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.456 | |
| 3s3r | 0IW | Cathepsin B-like peptidase (C01 family) | / | 0.456 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 3up0 | D7S | aceDAF-12 | / | 0.456 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.455 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.455 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.455 | |
| 3nu4 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.455 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.455 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.455 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.454 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.454 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.454 | |
| 3uka | FAD | UDP-galactopyranose mutase | / | 0.454 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.454 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.454 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.454 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.454 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 4qgi | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.453 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.453 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.453 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.453 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.453 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.453 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.453 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.452 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2r3t | G4G | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.452 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.452 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.452 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.452 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.452 | |
| 3ohf | 3HF | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.452 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.451 | |
| 3bva | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3nyg | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.451 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4irn | FAD | AnaB | / | 0.451 | |
| 4kb9 | G79 | Protease | / | 0.451 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.450 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.450 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.450 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3ieu | GDP | GTPase Era | / | 0.450 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3wag | TYD | Glycosyltransferase | / | 0.450 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.450 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.450 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.449 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.449 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.449 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.448 | |
| 1gqt | ACP | Ribokinase | / | 0.448 | |
| 1iiq | 0ZR | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.448 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.448 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.448 | |
| 3d1y | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.448 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.448 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.448 | |
| 4dl9 | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.448 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.448 | |
| 1fej | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.447 | |
| 1rv1 | IMZ | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.447 | |
| 2fxd | DR7 | Pol polyprotein | / | 0.447 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.447 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.447 | |
| 4kvm | SER_ALA_SER_GLU_1XE | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.447 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.447 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.447 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.447 | |
| 5dp2 | NAP | CurF | / | 0.447 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.446 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.446 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.446 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3umo | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.446 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.446 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.445 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.445 | |
| 1yxq | SWI | Actin, alpha skeletal muscle | / | 0.445 | |
| 2fxe | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2i4x | KGQ | Protease | / | 0.445 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.445 | |
| 3cyx | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3ekp | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3qaa | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3zkp | ERB | Erythromycin C-12 hydroxylase | 1.14.13.154 | 0.445 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.445 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.445 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.445 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1z1r | HBH | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.444 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.444 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.444 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.444 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.444 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.444 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.444 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.444 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.444 | |
| 4h49 | L29 | Macrophage metalloelastase | 3.4.24.65 | 0.444 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.443 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 2qnn | QN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3liq | E14 | Protease | / | 0.443 | |
| 3liv | E16 | Protease | / | 0.443 | |
| 3nu3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.443 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.443 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1idb | 0DO | Gag-Pol polyprotein | / | 0.442 | |
| 2bhh | RYU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.442 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.442 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.442 | |
| 3q5l | KX2 | Heat shock protein 83-1 | / | 0.442 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.442 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4gdd | FAD | UDP-galactopyranose mutase | / | 0.442 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 5eox | ADP | Type 4 fimbrial biogenesis protein PilM | / | 0.442 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2f81 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3kdd | JZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3o9g | F53 | Gag-Pol polyprotein | / | 0.441 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.441 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.441 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.441 | |
| 5cts | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.441 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.440 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.440 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.440 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.440 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.440 | |
| 3gga | GGW | Gag-Pol polyprotein | / | 0.440 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.440 | |
| 3lin | E13 | Protease | / | 0.440 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.440 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.440 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.440 | |
| 4hdf | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 |