scPDB - Distribution of Binding site Similarity values of 3l06 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3l06	SN0	N-acetylornithine carbamoyltransferase	2.1.3.9

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3l06	SN0	N-acetylornithine carbamoyltransferase	2.1.3.9	1.000
3l05	SN0	N-acetylornithine carbamoyltransferase	2.1.3.9	0.845
3kzo	AN0	N-acetylornithine carbamoyltransferase	2.1.3.9	0.710
3l04	SN0	N-acetylornithine carbamoyltransferase	2.1.3.9	0.700
3m4n	PA9	N-acetylornithine carbamoyltransferase	2.1.3.9	0.524
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.481
4eso	NAP	Putative oxidoreductase	/	0.481
1gj5	130	Prothrombin	3.4.21.5	0.480
1h60	STR	Pentaerythritol tetranitrate reductase	/	0.480
4pzs	ACO	Histone acetyltransferase p300	/	0.475
2wo7	ASV	Isopenicillin N synthase	1.21.3.1	0.472
2yq9	2AM	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.472
2qw0	34Z	4-chlorobenzoyl CoA ligase	/	0.469
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.469
3eu5	GBO	Protein farnesyltransferase subunit beta	2.5.1.58	0.468
3h3t	16H	Collagen type IV alpha-3-binding protein	/	0.467
1xom	CIO	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.466
3ba6	AN2	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.466
2cn0	F25	Prothrombin	3.4.21.5	0.465
4bfu	ZVU	Pantothenate kinase	2.7.1.33	0.465
1oc1	ASV	Isopenicillin N synthase	1.21.3.1	0.464
1ypg	UIR	Prothrombin	3.4.21.5	0.464
1w1w	AGS	Structural maintenance of chromosomes protein 1	/	0.463
4dyp	0MS	Nucleoprotein	/	0.463
1lke	DOG	Bilin-binding protein	/	0.462
1d3p	BT3	Prothrombin	3.4.21.5	0.461
3h3r	14H	Collagen type IV alpha-3-binding protein	/	0.461
5doz	NDP	JamJ	/	0.461
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.460
1n95	HFP	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	/	0.460
1n95	HFP	Protein farnesyltransferase subunit beta	2.5.1.58	0.460
4x7u	ZM3	Mycinamicin III 3''-O-methyltransferase	2.1.1.237	0.460
5bn3	ADP	V-type ATP synthase alpha chain	/	0.460
5bn3	ADP	NEQ263	/	0.460
1b2l	NDC	Alcohol dehydrogenase	1.1.1.1	0.459
2fm5	M99	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.459
1icv	FMN	Oxygen-insensitive NAD(P)H nitroreductase	/	0.458
2x7h	PFN	Prostaglandin reductase 3	1	0.458
3vf6	0H6	Glucokinase	2.7.1.2	0.458
4a6r	TA8	Probable aminotransferase	/	0.458
1uae	UD1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.457
1ype	UIP	Prothrombin	3.4.21.5	0.457
3h1v	TK1	Glucokinase	2.7.1.2	0.457
4ez8	DHF	Thymidylate synthase	2.1.1.45	0.457
2nom	DUT	Poly(A) polymerase, putative	/	0.456
4pzr	COA	Histone acetyltransferase p300	/	0.456
2zat	NAP	Dehydrogenase/reductase SDR family member 4	1.1.1.184	0.455
4ax9	N5N	Prothrombin	3.4.21.5	0.455
4tyq	AP5	Adenylate kinase	/	0.455
5std	UNN	Scytalone dehydratase	4.2.1.94	0.455
1wpg	ADP	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.454
3mjr	AC2	Deoxycytidine kinase	2.7.1.74	0.454
1gj4	132	Prothrombin	3.4.21.5	0.453
1wsv	THH	Aminomethyltransferase, mitochondrial	/	0.453
3zku	HCV	Isopenicillin N synthase	1.21.3.1	0.453
2d3a	ADP	Glutamine synthetase root isozyme 3	6.3.1.2	0.452
3hl0	NAD	Maleylacetate reductase	/	0.452
4wfr	2AM	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.452
1a4i	NDP	C-1-tetrahydrofolate synthase, cytoplasmic	1.5.1.5	0.451
1oyt	FSN	Prothrombin	3.4.21.5	0.451
3lfz	ADP	Uncharacterized protein MJ1225	/	0.451
4jyz	ATP	Glutamine--tRNA ligase	6.1.1.18	0.451
4lb2	DM5	Serum albumin	/	0.451
4bfz	ZVZ	Pantothenate kinase	2.7.1.33	0.450
3b9l	AZZ	Serum albumin	/	0.449
3hdy	GDU	UDP-galactopyranose mutase	/	0.449
3zg6	APR	NAD-dependent protein deacetylase sirtuin-6	3.5.1	0.449
4cuk	NAI	D-lactate dehydrogenase	/	0.449
1m2g	APR	NAD-dependent protein deacylase 1	/	0.448
2g25	TDK	Pyruvate dehydrogenase E1 component	1.2.4.1	0.448
3p2o	NAD	Bifunctional protein FolD	/	0.448
3ukf	GDU	UDP-galactopyranose mutase	/	0.448
1o2g	696	Prothrombin	3.4.21.5	0.447
2gvd	FKP	Adenylate cyclase type 2	/	0.447
2gvd	FKP	Adenylate cyclase type 5	/	0.447
3biy	01K	Histone acetyltransferase p300	/	0.447
3ckq	UPG	Glucosyl-3-phosphoglycerate synthase	2.4.1.266	0.447
3mey	ATP	Amino acid--[acyl-carrier-protein] ligase 1	6.2.1.n2	0.447
4ctj	SAM	Genome polyprotein	/	0.447
2vat	COA	Acetyl-CoA--deacetylcephalosporin C acetyltransferase	2.3.1.175	0.446
3h4v	DVP	Pteridine reductase 1	1.5.1.33	0.446
3sl2	ATP	Sensor histidine kinase WalK	/	0.446
4dan	2FA	Purine nucleoside phosphorylase DeoD-type	2.4.2.1	0.446
4ddl	0JQ	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.446
4rvg	TYD	D-mycarose 3-C-methyltransferase	/	0.446
1a9c	GTP	GTP cyclohydrolase 1	3.5.4.16	0.445
1f20	FAD	Nitric oxide synthase, brain	1.14.13.39	0.445
1xh8	R55	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.445
2ouu	35G	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.445
3dp9	BIG	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	/	0.445
4bge	PYW	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.445
4cth	RDF	Neprilysin	/	0.445
4dlc	UMP	Deoxyuridine triphosphatase, putative	/	0.445
2oth	NIM	Basic phospholipase A2 VRV-PL-VIIIa	3.1.1.4	0.444
3fgo	ACP	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.444
3h3s	H15	Collagen type IV alpha-3-binding protein	/	0.444
3qv1	NAD	Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic	1.2.1.13	0.444
4gyz	D5M	Tyrosyl-DNA phosphodiesterase 2	3.1.4	0.444
4i1n	FOL	Dihydrofolate reductase	1.5.1.3	0.444
4jlm	1NN	Deoxycytidine kinase	2.7.1.74	0.444
1ejb	INJ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.443
1nqv	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.443
1o5g	CR9	Prothrombin	3.4.21.5	0.443
1zg3	2HI	Isoflavone 4'-O-methyltransferase	/	0.443
1zgc	A2E	Acetylcholinesterase	3.1.1.7	0.443
2bf7	HBI	Pteridine reductase 1	1.5.1.33	0.443
3e32	ED2	Protein farnesyltransferase subunit beta	2.5.1.58	0.443
1e92	HBI	Pteridine reductase 1	1.5.1.33	0.442
1mvs	DTM	Dihydrofolate reductase	1.5.1.3	0.442
1n95	FTH	Protein farnesyltransferase subunit beta	2.5.1.58	0.442
1vkg	CRI	Histone deacetylase 8	3.5.1.98	0.442
2od7	A1R	NAD-dependent protein deacetylase HST2	3.5.1	0.442
3gwf	NAP	Cyclohexanone monooxygenase	/	0.442
3phj	DHK	Shikimate dehydrogenase (NADP(+))	/	0.442
1d6w	00R	Prothrombin	3.4.21.5	0.441
1tj0	FAD	Bifunctional protein PutA	1.5.5.2	0.441
3gnc	QQQ	Glutaryl-CoA dehydrogenase	/	0.441
3qj5	022	Alcohol dehydrogenase class-3	1.1.1.1	0.441
4uug	PXG	Branched-chain amino acid aminotransferase, putative	/	0.441
1oyn	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.440
1x2h	LPA	Lipoate-protein ligase A	6.3.1.20	0.440
1yqz	COA	Coenzyme A disulfide reductase	/	0.440
2ek4	SAH	Diphthine synthase	/	0.440
2v5a	LZL	Biotin carboxylase	6.3.4.14	0.440
3njo	PYV	Abscisic acid receptor PYR1	/	0.440