sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3bqd | DAY | Glucocorticoid receptor |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3bqd | DAY | Glucocorticoid receptor | / | 1.000 | |
| 1m2z | DEX | Glucocorticoid receptor | / | 0.555 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.537 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.537 | |
| 1p93 | DEX | Glucocorticoid receptor | / | 0.527 | |
| 3mnp | DEX | Glucocorticoid receptor | / | 0.522 | |
| 4udc | DEX | Glucocorticoid receptor | / | 0.519 | |
| 2abi | 1CA | Mineralocorticoid receptor | / | 0.517 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.508 | |
| 3mne | DEX | Glucocorticoid receptor | / | 0.508 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.504 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.501 | |
| 2ab2 | SNL | Mineralocorticoid receptor | / | 0.498 | |
| 3mno | DEX | Glucocorticoid receptor | / | 0.498 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.497 | |
| 3zrb | ORC | Progesterone receptor | / | 0.497 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.496 | |
| 2aa7 | 1CA | Mineralocorticoid receptor | / | 0.493 | |
| 3zrb | OR8 | Progesterone receptor | / | 0.492 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.492 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.488 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.488 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.487 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.486 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 3d90 | NOG | Progesterone receptor | / | 0.485 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.484 | |
| 3zr7 | OR8 | Progesterone receptor | / | 0.484 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 2aa6 | STR | Mineralocorticoid receptor | / | 0.483 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.482 | |
| 3vhu | SNL | Mineralocorticoid receptor | / | 0.481 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.480 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 2a3i | C0R | Mineralocorticoid receptor | / | 0.479 | |
| 2aa5 | STR | Mineralocorticoid receptor | / | 0.479 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.479 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.478 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.477 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.477 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.477 | |
| 2w8y | 486 | Progesterone receptor | / | 0.476 | |
| 4p6x | HCY | Glucocorticoid receptor | / | 0.476 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.475 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.473 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.473 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.473 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.472 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.472 | |
| 2w8y | NDR | Progesterone receptor | / | 0.471 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.471 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.471 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.470 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.469 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.469 | |
| 1e3k | R18 | Progesterone receptor | / | 0.468 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.468 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.468 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.468 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.468 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.467 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.466 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.466 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.466 | |
| 4apu | A2K | Progesterone receptor | / | 0.465 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.465 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.465 | |
| 2wpx | ACO | Orf14 | / | 0.464 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.464 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.463 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.463 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.463 | |
| 1jut | LYD | Thymidylate synthase | / | 0.462 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.462 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.462 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.462 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.461 | |
| 2amb | 17H | Androgen receptor | / | 0.461 | |
| 2iut | AGS | DNA translocase FtsK | / | 0.461 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.461 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.461 | |
| 3up0 | D7S | aceDAF-12 | / | 0.461 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4iah | 1DX | Alr2278 protein | / | 0.461 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2jfz | 003 | Glutamate racemase | / | 0.460 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.460 | |
| 3zra | ORB | Progesterone receptor | / | 0.460 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.460 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.460 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.460 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.460 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1fml | RTL | Retinol dehydratase | / | 0.459 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.459 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.459 | |
| 4apu | OR8 | Progesterone receptor | / | 0.459 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.458 | |
| 2aa2 | AS4 | Mineralocorticoid receptor | / | 0.458 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 3up3 | XCA | aceDAF-12 | / | 0.458 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.458 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.457 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.457 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.457 | |
| 3lu8 | IQX | Serum albumin | / | 0.457 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.456 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.456 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.456 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.456 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.456 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.456 | |
| 1y9r | 1CA | Mineralocorticoid receptor | / | 0.455 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.455 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.454 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.454 | |
| 1ppj | ANY | Cytochrome b | / | 0.454 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1sqn | NDR | Progesterone receptor | / | 0.454 | |
| 1zdw | FLV | Prenyltransferase | / | 0.454 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.454 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.454 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.453 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.453 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.453 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.453 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.453 | |
| 3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.453 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.453 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.452 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.452 | |
| 5doz | NDP | JamJ | / | 0.452 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1f4e | TPR | Thymidylate synthase | / | 0.451 | |
| 1zuc | T98 | Progesterone receptor | / | 0.451 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.451 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.451 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.451 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.451 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.451 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.450 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.450 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.450 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.450 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.450 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.450 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.450 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.450 | |
| 3qly | 55V | Uncharacterized protein | / | 0.450 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.450 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.450 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.450 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.450 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.449 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.449 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.449 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.449 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.449 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.449 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.449 | |
| 1eio | GCH | Gastrotropin | / | 0.448 | |
| 1err | RAL | Estrogen receptor | / | 0.448 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.448 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.448 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.448 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.448 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.448 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.448 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.448 | |
| 4awi | AQ2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.448 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.448 | |
| 4l9k | EHF | Serum albumin | / | 0.448 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.448 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.448 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.447 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.447 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.447 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.447 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.446 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.446 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.446 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.446 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.446 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.446 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.446 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.445 | |
| 1x7r | GEN | Estrogen receptor | / | 0.445 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.445 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.445 | |
| 2piu | DHT | Androgen receptor | / | 0.445 | |
| 2pkl | DHT | Androgen receptor | / | 0.445 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.445 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.445 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.445 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.445 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.445 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.445 | |
| 4l9q | 9TP | Serum albumin | / | 0.445 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.445 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.445 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.445 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.444 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.444 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.444 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.444 | |
| 1xj7 | DHT | Androgen receptor | / | 0.444 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.444 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
| 2pio | DHT | Androgen receptor | / | 0.444 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.444 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.444 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.444 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.444 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.444 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.443 | |
| 2piv | DHT | Androgen receptor | / | 0.443 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.443 | |
| 2ylo | TES | Androgen receptor | / | 0.443 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.443 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.443 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.443 | |
| 4iae | 1DX | Alr2278 protein | / | 0.443 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.443 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.443 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1tw2 | ERT | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.442 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.442 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.442 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.442 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.442 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.442 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4b1f | KRH | Glutamate racemase | / | 0.442 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.442 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.442 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.441 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.441 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1s9p | DES | Estrogen-related receptor gamma | / | 0.441 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.441 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.441 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
| 2pix | DHT | Androgen receptor | / | 0.441 | |
| 3cse | N22 | Uncharacterized protein | / | 0.441 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.441 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.441 | |
| 3zuy | TCH | Transporter | / | 0.441 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.441 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.441 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.440 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.440 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.440 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.440 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.440 | |
| 3zqt | TES | Androgen receptor | / | 0.440 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.440 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.440 | |
| 4njt | 017 | Protease | / | 0.440 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.440 |