sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 1.466 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 1.006 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.932 | |
| 1sny | NAP | LD36273p | / | 0.921 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.918 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.902 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.897 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.893 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.892 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.871 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.870 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.846 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.835 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.831 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.831 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.828 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.825 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.824 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.820 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.809 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.807 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.805 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.803 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.803 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.803 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.800 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.798 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.798 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.798 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.797 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.796 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.796 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.795 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.795 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.794 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.792 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.791 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.789 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.789 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.788 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.788 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.788 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.787 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.787 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.785 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.784 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.783 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.782 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.782 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.780 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.780 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.778 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.778 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.777 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.777 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.775 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.773 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.772 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.771 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.768 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.766 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.765 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.765 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.764 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.764 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.763 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.763 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.763 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.762 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.762 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.762 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.761 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.761 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.759 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.758 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.757 | |
| 4kwh | NAP | Reductase homolog | / | 0.757 | |
| 3mje | NDP | AmphB | / | 0.756 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.755 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.755 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.754 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.752 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.752 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.751 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.751 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.748 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.746 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.745 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.745 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.745 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.744 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.743 | |
| 1iy8 | NAD | Levodione reductase | / | 0.741 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.741 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.740 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.739 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.739 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.737 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.737 | |
| 3sju | NDP | Keto reductase | / | 0.736 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.736 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.736 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.735 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.734 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.734 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.734 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.731 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.730 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.730 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.729 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.728 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.728 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.727 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.727 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.726 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.726 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.725 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.724 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.724 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.724 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.723 | |
| 4qed | NAP | ElxO | / | 0.723 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.722 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.722 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.722 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.721 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.720 | |
| 4fda | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.720 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.719 | |
| 3uce | NDP | Dehydrogenase | / | 0.719 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.718 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.716 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.716 | |
| 4ccq | NAP | Thioredoxin reductase | / | 0.714 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.713 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.713 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.713 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.712 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.712 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.712 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.711 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.710 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.710 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.709 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.709 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.709 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.709 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.708 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.707 | |
| 3s5w | NAP | L-ornithine N(5)-monooxygenase | / | 0.707 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.706 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.705 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.705 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.705 | |
| 4u7w | NDP | MxaA | / | 0.705 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.703 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.703 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.702 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.700 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.700 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.697 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.696 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.695 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.695 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.695 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.694 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.693 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.693 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.693 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.693 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.693 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.692 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.692 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.691 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.691 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.690 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.686 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.685 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.685 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.685 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.684 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.684 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.684 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.683 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.683 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.683 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.682 | |
| 2iyp | A2P | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.682 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.682 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.678 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.678 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.677 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.677 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.677 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.677 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.677 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.676 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.676 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.674 | |
| 4qec | NAP | ElxO | / | 0.674 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.673 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.673 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.673 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.672 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.672 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.672 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.671 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.670 | |
| 3lzx | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.670 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.668 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.668 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.668 | |
| 4clo | NAP | Pteridine reductase | / | 0.668 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.667 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.667 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.667 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.667 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.666 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.666 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.666 | |
| 5d2e | NAP | MlnE | / | 0.666 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.664 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.663 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.663 | |
| 4cnz | ADP | Nitrogen regulatory protein P-II 1 | / | 0.663 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.661 | |
| 5a04 | NDP | Glucose-fructose oxidoreductase | / | 0.661 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.660 | |
| 1h6a | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.659 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.659 | |
| 2hk9 | ATR | Shikimate dehydrogenase (NADP(+)) | / | 0.659 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.658 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.658 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.657 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.657 | |
| 5a06 | NDP | Glucose-fructose oxidoreductase | / | 0.657 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.656 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.656 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.655 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.655 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.655 | |
| 3qfc | NAP | NADPH--cytochrome P450 reductase | / | 0.655 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.655 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.654 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.653 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.653 | |
| 4a5l | NDP | Thioredoxin reductase | / | 0.652 | |
| 4to4 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.652 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.651 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.651 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.651 |