sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xls | FAD | Putative flavin-containing monooxygenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 1.377 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 1.202 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 1.197 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 1.190 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 1.179 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 1.131 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 1.129 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 1.104 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 1.043 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.780 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.779 | |
| 2ylt | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.774 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.770 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.769 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.768 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.766 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.763 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.759 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.752 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.749 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.748 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.746 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.744 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.742 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.740 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.739 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.739 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.737 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.729 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.729 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.725 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.724 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.721 | |
| 2qa1 | FAD | PgaE | / | 0.720 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.720 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.720 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.720 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.718 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.717 | |
| 3rha | FDA | Putrescine oxidase | / | 0.713 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.712 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.711 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.710 | |
| 3ukk | FDA | UDP-galactopyranose mutase | / | 0.709 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.708 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.706 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.706 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.704 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.703 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.703 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.699 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.698 | |
| 4u8k | FDA | UDP-galactopyranose mutase | / | 0.697 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.696 | |
| 3ukl | FAD | UDP-galactopyranose mutase | / | 0.695 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.694 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.693 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.692 | |
| 4tm3 | FAD | KtzI | / | 0.692 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.690 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.689 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.689 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.689 | |
| 4tlz | FAD | KtzI | / | 0.689 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.686 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.686 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.686 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.685 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.685 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.684 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.684 | |
| 2bab | FAD | Putative aminooxidase | / | 0.683 | |
| 4u8p | FDA | UDP-galactopyranose mutase | / | 0.683 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.682 | |
| 3utf | FDA | UDP-galactopyranose mutase | / | 0.682 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.681 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.681 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.680 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.680 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.680 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.679 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.678 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.678 | |
| 4tlx | FDA | KtzI | / | 0.678 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.677 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.677 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.676 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.676 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.676 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.676 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.675 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.674 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.673 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.673 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.672 | |
| 4k5r | FAD | Oxygenase | / | 0.672 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.671 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.670 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.669 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.668 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.668 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.668 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.668 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.668 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.667 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.667 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.667 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.667 | |
| 4icy | FAD | PgaE | / | 0.667 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.666 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.665 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.664 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.663 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.663 | |
| 4u8j | FDA | UDP-galactopyranose mutase | / | 0.663 | |
| 4u8n | FDA | UDP-galactopyranose mutase | / | 0.663 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.662 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.661 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.661 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.661 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.660 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.660 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.659 | |
| 4u8o | FDA | UDP-galactopyranose mutase | / | 0.657 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.656 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.655 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.655 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.654 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.654 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.654 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.654 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.654 | |
| 4u8l | FDA | UDP-galactopyranose mutase | / | 0.654 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.653 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.653 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.653 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.652 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.652 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.651 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.651 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.651 | |
| 3uth | FDA | UDP-galactopyranose mutase | / | 0.650 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.650 |