sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2gr1 | FAD | Ferredoxin reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2gr1 | FAD | Ferredoxin reductase | / | 1.487 | |
| 2yvf | FAD | Ferredoxin reductase | / | 1.463 | |
| 4h4y | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.459 | |
| 4h4s | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.455 | |
| 4h4w | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.407 | |
| 4h4u | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.377 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.355 | |
| 4h50 | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.345 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.167 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.167 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.163 | |
| 2gqw | FAD | Ferredoxin reductase | / | 1.155 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 1.149 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 1.145 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.144 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.113 | |
| 1d7y | FAD | Ferredoxin reductase | / | 1.087 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 1.078 | |
| 1f3p | FAD | Ferredoxin reductase | / | 1.006 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.890 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.874 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.866 | |
| 2yvj | FAD | Ferredoxin reductase | / | 0.864 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.861 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.860 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.844 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.840 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.839 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.820 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.815 | |
| 3rha | FDA | Putrescine oxidase | / | 0.799 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.790 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.766 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.762 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.759 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.755 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.753 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.752 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.751 | |
| 3gd3 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.748 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.747 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.743 | |
| 4emw | FAD | Coenzyme A disulfide reductase | / | 0.742 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.740 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.732 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.732 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.728 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.727 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.725 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.722 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.719 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.719 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.718 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.717 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.717 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.717 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.716 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.716 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.715 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.714 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.712 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.711 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.711 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.711 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.710 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.707 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.706 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.704 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.703 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.703 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.702 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.702 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.700 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.700 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.699 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.698 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.698 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.697 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.695 | |
| 4nte | FAD | DepH | / | 0.695 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.694 | |
| 3ihg | FAD | Aklavinone 12-hydroxylase RdmE | / | 0.693 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.691 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.691 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.691 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.691 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.690 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.688 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.688 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.687 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.686 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.685 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.684 | |
| 2cdu | FAD | NADH oxidase | / | 0.683 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.682 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.680 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.680 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.678 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.678 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.674 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.673 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.673 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.672 | |
| 4rje | FNR | Lactate oxidase | / | 0.672 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.669 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.668 | |
| 3fbs | FAD | Oxidoreductase | / | 0.668 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.668 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.665 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.665 | |
| 4txi | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.665 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.664 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.663 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.663 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.663 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.662 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.661 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.660 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.660 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.660 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.659 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.659 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.659 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.658 | |
| 4u8o | FDA | UDP-galactopyranose mutase | / | 0.658 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.657 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.657 | |
| 4jn9 | FAD | DepH | / | 0.656 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.656 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.655 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.655 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.655 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.655 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.655 | |
| 3qj4 | FAD | Renalase | / | 0.654 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.654 | |
| 4x4j | FAD | Putative oxygenase | / | 0.654 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.653 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.653 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.653 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.653 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.653 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.652 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.652 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.652 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.652 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.652 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.651 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.651 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.651 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.651 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.651 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.651 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.651 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.651 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.650 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.650 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.650 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.650 |