sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 1.355 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.940 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.918 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.917 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.895 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.894 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.888 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.888 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.878 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.877 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.876 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.873 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.871 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.863 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.858 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.851 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.848 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.845 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.843 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.843 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.843 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.840 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.837 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.836 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.835 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.830 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.829 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.826 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.824 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.824 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.823 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.818 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.817 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.815 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.811 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.811 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.810 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.810 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.809 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.809 | |
| 4kwh | NAP | Reductase homolog | / | 0.808 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.808 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.806 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.801 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.797 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.796 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.796 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.794 | |
| 1sny | NAP | LD36273p | / | 0.792 | |
| 3sju | NDP | Keto reductase | / | 0.792 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.792 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.790 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.790 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.789 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.788 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.788 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.788 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.788 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.786 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.785 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.785 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.780 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.779 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.779 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.778 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.776 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.774 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.774 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.773 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.773 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.773 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.769 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.769 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.768 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.768 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.767 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.764 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.763 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.763 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.762 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.761 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.760 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.759 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.759 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.758 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.758 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.757 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.757 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.757 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.755 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.755 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.753 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.751 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.751 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.751 | |
| 4qed | NAP | ElxO | / | 0.748 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.747 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.744 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.742 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.741 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.737 | |
| 4u7w | NDP | MxaA | / | 0.732 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.731 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.730 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.727 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.727 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.726 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.726 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.726 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.726 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.724 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.724 | |
| 5d2e | NAP | MlnE | / | 0.724 | |
| 4qec | NAP | ElxO | / | 0.723 | |
| 4hxy | NDP | Plm1 | / | 0.722 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.720 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.719 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.719 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.718 | |
| 1iy8 | NAD | Levodione reductase | / | 0.718 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.717 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.717 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.715 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.713 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.713 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.713 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.712 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.712 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.709 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.709 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.706 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.706 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.705 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.705 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.704 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.700 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.699 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.699 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.699 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.698 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.698 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.698 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.695 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.695 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.694 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.693 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.693 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.692 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.692 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.691 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.691 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.691 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.689 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.689 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.689 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.688 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.688 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.688 | |
| 4h0u | UMP | Thymidylate synthase | / | 0.687 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.686 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.683 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.682 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.682 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.682 | |
| 3pdu | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.682 | |
| 3mje | NDP | AmphB | / | 0.681 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.681 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.680 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.680 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.680 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.680 | |
| 3baz | NAP | Hydroxyphenylpyruvate reductase | 1.1.1.237 | 0.679 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.677 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.676 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.676 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.675 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.675 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.673 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.672 | |
| 3bmo | NAP | Pteridine reductase | / | 0.672 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.671 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.670 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.669 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.669 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.669 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.668 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.668 | |
| 4clo | NAP | Pteridine reductase | / | 0.667 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.667 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.667 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.666 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.666 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.666 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.666 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.665 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.665 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.664 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.663 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.663 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.663 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.662 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.661 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.661 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.661 | |
| 5j23 | A2R | Putative 2-hydroxyacid dehydrogenase | / | 0.661 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.659 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.658 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.658 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.658 | |
| 1aj2 | 2PH | Dihydropteroate synthase | / | 0.657 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.657 | |
| 4xb2 | NDP | 319aa long hypothetical homoserine dehydrogenase | / | 0.657 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.656 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.656 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.655 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.654 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.654 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.653 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.653 | |
| 3uce | NDP | Dehydrogenase | / | 0.653 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.653 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.652 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.652 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.651 | |
| 4a5l | NDP | Thioredoxin reductase | / | 0.651 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.651 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.650 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.650 | |
| 5a03 | NDP | Glucose-fructose oxidoreductase | / | 0.650 |