Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1e3l NAD Alcohol dehydrogenase 4 1.1.1.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1e3l NADAlcohol dehydrogenase 4 1.1.1.1 1.099
4dlb NADS-(hydroxymethyl)glutathione dehydrogenase / 0.856
2oxi NADAlcohol dehydrogenase E chain 1.1.1.1 0.817
1adc PADAlcohol dehydrogenase E chain 1.1.1.1 0.816
4dl9 NADS-(hydroxymethyl)glutathione dehydrogenase / 0.814
3uko NADAlcohol dehydrogenase class-3 / 0.804
2ohx NADAlcohol dehydrogenase E chain 1.1.1.1 0.797
1hf3 NADAlcohol dehydrogenase E chain 1.1.1.1 0.795
4jji NADAlcohol dehydrogenase class-3 / 0.792
4xd2 NAIAlcohol dehydrogenase E chain 1.1.1.1 0.789
4l0q NADAlcohol dehydrogenase class-3 / 0.786
5kjf NAJAlcohol dehydrogenase E chain 1.1.1.1 0.781
1ma0 NADAlcohol dehydrogenase class-3 1.1.1.1 0.778
1axe NADAlcohol dehydrogenase E chain 1.1.1.1 0.775
1u3v NADAlcohol dehydrogenase 1B 1.1.1.1 0.775
2fzw NADAlcohol dehydrogenase class-3 1.1.1.1 0.771
1hsz NADAlcohol dehydrogenase 1B 1.1.1.1 0.768
1mgo NADAlcohol dehydrogenase E chain 1.1.1.1 0.767
2jhf NADAlcohol dehydrogenase E chain 1.1.1.1 0.767
5kjc NAJAlcohol dehydrogenase E chain 1.1.1.1 0.767
1heu NADAlcohol dehydrogenase E chain 1.1.1.1 0.766
5kj6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.766
3cos NADAlcohol dehydrogenase 4 1.1.1.1 0.765
1cdo NADAlcohol dehydrogenase 1 1.1.1.1 0.764
1ht0 NADAlcohol dehydrogenase 1C 1.1.1.1 0.764
4rqu NADAlcohol dehydrogenase class-P / 0.763
1het NADAlcohol dehydrogenase E chain 1.1.1.1 0.761
1mp0 NADAlcohol dehydrogenase class-3 1.1.1.1 0.761
6adh NADAlcohol dehydrogenase E chain 1.1.1.1 0.759
4dwv NAJAlcohol dehydrogenase E chain 1.1.1.1 0.757
4dxh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.757
5cds NAJAlcohol dehydrogenase E chain 1.1.1.1 0.757
5kcz NAJAlcohol dehydrogenase E chain 1.1.1.1 0.757
1f8f NADBenzyl alcohol dehydrogenase / 0.756
1lde NADAlcohol dehydrogenase E chain 1.1.1.1 0.756
1axg NADAlcohol dehydrogenase E chain 1.1.1.1 0.752
3oq6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.752
5kj1 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.752
4gl4 NAIAlcohol dehydrogenase class-3 / 0.749
1uxk NADMalate dehydrogenase / 0.745
5cdt NAJAlcohol dehydrogenase E chain 1.1.1.1 0.743
5kcp NAJAlcohol dehydrogenase E chain 1.1.1.1 0.743
4nfh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.742
5cdg NAJAlcohol dehydrogenase E chain 1.1.1.1 0.742
2vhx NADAlanine dehydrogenase 1.4.1.1 0.739
5kje NAJAlcohol dehydrogenase E chain 1.1.1.1 0.737
2fze APRAlcohol dehydrogenase class-3 1.1.1.1 0.736
1hdz NADAlcohol dehydrogenase 1B 1.1.1.1 0.732
4oaq NDPR-specific carbonyl reductase / 0.731
1a71 NADAlcohol dehydrogenase E chain 1.1.1.1 0.730
1adb CNDAlcohol dehydrogenase E chain 1.1.1.1 0.727
4nfs NAJAlcohol dehydrogenase E chain 1.1.1.1 0.727
3wle NAD(R)-specific carbonyl reductase / 0.726
3jv7 NADSecondary alcohol dehydrogenase / 0.724
1h2b NAJNAD-dependent alcohol dehydrogenase / 0.722
2vhz NAIAlanine dehydrogenase 1.4.1.1 0.722
1uxj NADMalate dehydrogenase / 0.720
3x2f NAIAdenosylhomocysteinase / 0.719
1hld NADAlcohol dehydrogenase E chain 1.1.1.1 0.715
1hyh NADL-2-hydroxyisocaproate dehydrogenase / 0.714
4nd3 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.713
4ng5 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.711
1agn NADAlcohol dehydrogenase class 4 mu/sigma chain 1.1.1.1 0.710
2d8a NADL-threonine 3-dehydrogenase / 0.708
2dph NADFormaldehyde dismutase / 0.708
1e3e NAIAlcohol dehydrogenase 4 1.1.1.1 0.707
2vhw NAIAlanine dehydrogenase 1.4.1.1 0.706
4okn NAIL-lactate dehydrogenase A chain 1.1.1.27 0.706
1il0 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.705
1r37 NADNAD-dependent alcohol dehydrogenase 1.1.1.1 0.705
2fn7 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.704
2vhv NAIAlanine dehydrogenase 1.4.1.1 0.703
1t2c NAIL-lactate dehydrogenase 1.1.1.27 0.702
1kol NADGlutathione-independent formaldehyde dehydrogenase / 0.700
4nd4 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.699
1pl8 NADSorbitol dehydrogenase 1.1.1.14 0.698
4gkv NADAlcohol dehydrogenase, propanol-preferring 1.1.1.1 0.698
1m76 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.696
1t2d NADL-lactate dehydrogenase 1.1.1.27 0.696
2xaa NADSecondary alcohol dehydrogenase / 0.696
3h3j NADL-lactate dehydrogenase 1 1.1.1.27 0.696
2voj NADAlanine dehydrogenase 1.4.1.1 0.693
2aa3 AP0L-lactate dehydrogenase / 0.690
4ejm NAPPutative zinc-binding dehydrogenase / 0.688
4l4s NAIL-lactate dehydrogenase A chain 1.1.1.27 0.688
4jnk NAIL-lactate dehydrogenase A chain 1.1.1.27 0.687
3m6i NADL-arabinitol 4-dehydrogenase 1.1.1.12 0.686
1vsv NADGlyceraldehyde-3-phosphate dehydrogenase / 0.685
4uun NAIL-lactate dehydrogenase / 0.685
2eer NADNAD-dependent alcohol dehydrogenase 1.1.1.1 0.682
3ikt NADRedox-sensing transcriptional repressor Rex / 0.679
4cpd NADAlcohol dehydrogenase / 0.679
1pl6 NADSorbitol dehydrogenase 1.1.1.14 0.678
1wwk NAD307aa long hypothetical phosphoglycerate dehydrogenase / 0.678
2ejv NADL-threonine 3-dehydrogenase / 0.678
3kbo NDPGlyoxylate/hydroxypyruvate reductase A / 0.678
1lso NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.676
1u8f NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.673
2a92 NAIL-lactate dehydrogenase / 0.669
2dt5 NADRedox-sensing transcriptional repressor Rex / 0.669
4mdh NADMalate dehydrogenase, cytoplasmic 1.1.1.37 0.669
4w6z 8IDAlcohol dehydrogenase 1 1.1.1.1 0.669
1cer NADGlyceraldehyde-3-phosphate dehydrogenase / 0.666
1f0y NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.666
1teh NADAlcohol dehydrogenase class-3 1.1.1.1 0.666
1x7d NADPutative ornithine cyclodeaminase / 0.666
3wsw NADL-lactate dehydrogenase / 0.666
5c7o NADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific 1.2.1.12 0.666
2hu2 NADC-terminal binding protein 1 / 0.665
2qg4 NADUDP-glucose 6-dehydrogenase 1.1.1.22 0.664
3d4p NADL-lactate dehydrogenase 1 1.1.1.27 0.664
1bdm NAXMalate dehydrogenase / 0.663
1up7 NAD6-phospho-beta-glucosidase BglT 3.2.1.86 0.663
1u7h NADPutative ornithine cyclodeaminase / 0.662
1ur5 NADMalate dehydrogenase / 0.662
2d2i NAPGlyceraldehyde-3-phosphate dehydrogenase / 0.662
2a94 AP0L-lactate dehydrogenase 1.1.1.27 0.661
3zw9 NADPeroxisomal bifunctional enzyme 1.1.1.35 0.661
4c4o NADSADH / 0.660
2ep7 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.659
3gvh NADMalate dehydrogenase / 0.659
4z0p NDPNAD-dependent dehydrogenase / 0.658
1lsj NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.657
1yqd NAPSinapyl alcohol dehydrogenase / 0.657
4wlv NADMalate dehydrogenase, mitochondrial 1.1.1.37 0.657
1pjc NADAlanine dehydrogenase / 0.656
1sow NADL-lactate dehydrogenase 1.1.1.27 0.655
1yba NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.655
2dfd NADMalate dehydrogenase, mitochondrial 1.1.1.37 0.655
2g5c NADPrephenate dehydrogenase / 0.655
2cdc NAPGlucose 1-dehydrogenase / 0.653
3jyo NADQuinate/shikimate dehydrogenase (NAD(+)) / 0.653
2ldb NADL-lactate dehydrogenase 1.1.1.27 0.652
4lcj NADC-terminal-binding protein 2 / 0.652
1b8v NADMalate dehydrogenase / 0.651
1h2h NADL-aspartate dehydrogenase 1.4.1.21 0.651
2ph5 NADHomospermidine synthase / 0.651
1p0f NAPNADP-dependent alcohol dehydrogenase 1.1.1.2 0.650
1psd NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.650
1yqx NAPSinapyl alcohol dehydrogenase / 0.650
2o4c NADErythronate-4-phosphate dehydrogenase / 0.650
3pvz NADUDP-N-acetylglucosamine 4,6-dehydratase / 0.650