sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.819 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.804 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.791 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.791 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.774 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.766 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.764 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.747 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.743 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.739 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.734 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.722 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.602 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.585 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.577 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.574 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.563 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.562 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.561 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.558 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.556 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.556 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.555 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.554 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.541 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.529 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.527 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.524 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.520 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.517 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.514 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.513 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.511 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.504 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.504 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.499 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.495 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.492 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.491 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.491 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.487 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.486 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.485 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.485 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.484 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.481 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.481 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.480 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.480 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.478 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.475 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.475 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.472 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.470 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.470 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.467 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.467 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.467 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.467 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.463 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.461 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.460 | |
| 4iae | 1DX | Alr2278 protein | / | 0.460 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.459 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.459 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.459 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.459 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4nvk | 2NY | Peroxidase | / | 0.459 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.458 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.458 | |
| 4boe | CLR | Japanin | / | 0.458 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.458 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.457 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.457 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.457 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.456 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.456 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.454 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.453 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.453 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.453 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.453 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.453 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.452 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.452 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.451 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.451 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.449 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.449 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.448 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.448 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.448 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.447 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.447 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.447 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.445 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.445 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.444 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4iah | 1DX | Alr2278 protein | / | 0.444 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.444 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.443 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1s36 | CEI | Obelin | / | 0.443 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.443 | |
| 4h0v | NAD | Iota toxin component Ia | / | 0.443 | |
| 4rel | KMP | Glycosyltransferase | / | 0.443 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.442 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.442 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.442 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.442 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4n1g | CEI | Obelin | / | 0.442 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.442 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.441 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.441 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.441 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.441 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.441 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.441 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.440 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.440 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.440 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.440 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.440 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.440 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 |