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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1b39ATPCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1b39ATPCyclin-dependent kinase 22.7.11.221.000
2btrU73Cyclin-dependent kinase 22.7.11.220.602
3r1yX76Cyclin-dependent kinase 22.7.11.220.569
1b38ATPCyclin-dependent kinase 22.7.11.220.561
1hckATPCyclin-dependent kinase 22.7.11.220.542
2r3o2SCCyclin-dependent kinase 22.7.11.220.542
3r7yZ04Cyclin-dependent kinase 22.7.11.220.540
1h0vUN4Cyclin-dependent kinase 22.7.11.220.534
2r3p3SCCyclin-dependent kinase 22.7.11.220.532
4fkt48KCyclin-dependent kinase 22.7.11.220.527
2r3iSCFCyclin-dependent kinase 22.7.11.220.526
2r3r6SCCyclin-dependent kinase 22.7.11.220.524
3iggEFQCyclin-dependent kinase 22.7.11.220.521
2r3mSCXCyclin-dependent kinase 22.7.11.220.520
3r1sX73Cyclin-dependent kinase 22.7.11.220.516
2btsU32Cyclin-dependent kinase 22.7.11.220.514
4ek816KCyclin-dependent kinase 22.7.11.220.512
3lfqA28Cyclin-dependent kinase 22.7.11.220.511
4ek610KCyclin-dependent kinase 22.7.11.220.511
4fkpLS5Cyclin-dependent kinase 22.7.11.220.509
2r3gSC9Cyclin-dependent kinase 22.7.11.220.508
4fki09KCyclin-dependent kinase 22.7.11.220.505
1pxoCK7Cyclin-dependent kinase 22.7.11.220.503
2c6iDT1Cyclin-dependent kinase 22.7.11.220.502
3r7iX9ICyclin-dependent kinase 22.7.11.220.501
1vyzN5BCyclin-dependent kinase 22.7.11.220.498
1y91CT9Cyclin-dependent kinase 22.7.11.220.497
2c69CT8Cyclin-dependent kinase 22.7.11.220.497
1e1xNW1Cyclin-dependent kinase 22.7.11.220.496
2a4lRRCCyclin-dependent kinase 22.7.11.220.495
3ezvEZVCyclin-dependent kinase 22.7.11.220.495
3r7uX96Cyclin-dependent kinase 22.7.11.220.494
3ezrEZRCyclin-dependent kinase 22.7.11.220.493
3sqq99ZCyclin-dependent kinase 22.7.11.220.492
1e1vCMGCyclin-dependent kinase 22.7.11.220.491
1w8cN69Cyclin-dependent kinase 22.7.11.220.491
2c6o4SPCyclin-dependent kinase 22.7.11.220.491
3r7vZ02Cyclin-dependent kinase 22.7.11.220.491
1ke5LS1Cyclin-dependent kinase 22.7.11.220.490
4fkq42KCyclin-dependent kinase 22.7.11.220.490
3rm719ZCyclin-dependent kinase 22.7.11.220.487
3qqhX0ACyclin-dependent kinase 22.7.11.220.486
5aniES4Cyclin-dependent kinase 22.7.11.220.486
1qmzATPCyclin-dependent kinase 22.7.11.220.485
3lfsA07Cyclin-dependent kinase 22.7.11.220.485
3r73X87Cyclin-dependent kinase 22.7.11.220.485
2b52D42Cyclin-dependent kinase 22.7.11.220.484
3qwjX6ACyclin-dependent kinase 22.7.11.220.484
3qxoX65Cyclin-dependent kinase 22.7.11.220.483
3s2pPMUCyclin-dependent kinase 22.7.11.220.481
2r3jSCJCyclin-dependent kinase 22.7.11.220.480
1h1r6CPCyclin-dependent kinase 22.7.11.220.479
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.479
1gih1PUCyclin-dependent kinase 22.7.11.220.478
2fvdLIACyclin-dependent kinase 22.7.11.220.478
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.478
3fz1B98Cyclin-dependent kinase 22.7.11.220.478
4fklCK2Cyclin-dependent kinase 22.7.11.220.478
3lfnA27Cyclin-dependent kinase 22.7.11.220.476
3rak03ZCyclin-dependent kinase 22.7.11.220.476
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.474
4fkg4CKCyclin-dependent kinase 22.7.11.220.474
2a0cCK9Cyclin-dependent kinase 22.7.11.220.473
2r3fSC8Cyclin-dependent kinase 22.7.11.220.473
2r3kSCQCyclin-dependent kinase 22.7.11.220.473
2r3q5SCCyclin-dependent kinase 22.7.11.220.473
2uzoC62Cyclin-dependent kinase 22.7.11.220.472
1oitHDTCyclin-dependent kinase 22.7.11.220.471
1w0xOLOCyclin-dependent kinase 22.7.11.220.470
2r64740Cyclin-dependent kinase 22.7.11.220.470
3rm618ZCyclin-dependent kinase 22.7.11.220.470
1h0w207Cyclin-dependent kinase 22.7.11.220.469
3sw719KCyclin-dependent kinase 22.7.11.220.468
3qqfX07Cyclin-dependent kinase 22.7.11.220.467
3qzgX67Cyclin-dependent kinase 22.7.11.220.467
1gii1PUCyclin-dependent kinase 22.7.11.220.466
1ke6LS2Cyclin-dependent kinase 22.7.11.220.466
1p2a5BNCyclin-dependent kinase 22.7.11.220.466
3ddqRRCCyclin-dependent kinase 22.7.11.220.466
4nj32KDCyclin-dependent kinase 22.7.11.220.466
3r8vZ62Cyclin-dependent kinase 22.7.11.220.465
2vthLZ2Cyclin-dependent kinase 22.7.11.220.464
3r8lZ30Cyclin-dependent kinase 22.7.11.220.464
2exmZIPCyclin-dependent kinase 22.7.11.220.463
2uznC96Cyclin-dependent kinase 22.7.11.220.463
2xmyCDKCyclin-dependent kinase 22.7.11.220.463
3rk909ZCyclin-dependent kinase 22.7.11.220.463
2r3lSCWCyclin-dependent kinase 22.7.11.220.462
3pj8404Cyclin-dependent kinase 22.7.11.220.462
3qqlX03Cyclin-dependent kinase 22.7.11.220.462
3qzhX69Cyclin-dependent kinase 22.7.11.220.462
4ez30S0Cyclin-dependent kinase 22.7.11.220.462
1vyw292Cyclin-dependent kinase 22.7.11.220.461
1ykr628Cyclin-dependent kinase 22.7.11.220.459
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.459
1jstATPCyclin-dependent kinase 22.7.11.220.458
3r83Z14Cyclin-dependent kinase 22.7.11.220.458
3r8pZ46Cyclin-dependent kinase 22.7.11.220.458
3raiX85Cyclin-dependent kinase 22.7.11.220.458
3rpo24ZCyclin-dependent kinase 22.7.11.220.457
4fkj11KCyclin-dependent kinase 22.7.11.220.456
3qu0X40Cyclin-dependent kinase 22.7.11.220.455
3qziX72Cyclin-dependent kinase 22.7.11.220.454
4bgh3I6Cyclin-dependent kinase 22.7.11.220.454
1pxpCK8Cyclin-dependent kinase 22.7.11.220.453
3rjc06ZCyclin-dependent kinase 22.7.11.220.453
4bcpT3CCyclin-dependent kinase 22.7.11.220.453
4eon1ROCyclin-dependent kinase 22.7.11.220.453
1pxmCK5Cyclin-dependent kinase 22.7.11.220.452
2c5yMTWCyclin-dependent kinase 22.7.11.220.452
2b55D31Cyclin-dependent kinase 22.7.11.220.451
1h1s4SPCyclin-dependent kinase 22.7.11.220.450
3my5RFZCyclin-dependent kinase 22.7.11.220.450
3r6xX84Cyclin-dependent kinase 22.7.11.220.450
4fkr45KCyclin-dependent kinase 22.7.11.220.450
1ke7LS3Cyclin-dependent kinase 22.7.11.220.449
3ddpRC8Cyclin-dependent kinase 22.7.11.220.449
3r71X86Cyclin-dependent kinase 22.7.11.220.449
1ckpPVBCyclin-dependent kinase 22.7.11.220.447
3qtzX42Cyclin-dependent kinase 22.7.11.220.447
3r7eX88Cyclin-dependent kinase 22.7.11.220.447
1ke9LS5Cyclin-dependent kinase 22.7.11.220.446
1v1k3FPCyclin-dependent kinase 22.7.11.220.446
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.446
1ke8LS4Cyclin-dependent kinase 22.7.11.220.445
2vtqLZACyclin-dependent kinase 22.7.11.220.445
4acm7YGCyclin-dependent kinase 22.7.11.220.445
4lyn1YGCyclin-dependent kinase 22.7.11.220.445
1oiuN76Cyclin-dependent kinase 22.7.11.220.444
2iw84SPCyclin-dependent kinase 22.7.11.220.444
2j9mPY8Cyclin-dependent kinase 22.7.11.220.444
3pxyJWSCyclin-dependent kinase 22.7.11.220.444
3r9hZ67Cyclin-dependent kinase 22.7.11.220.444
1fvt106Cyclin-dependent kinase 22.7.11.220.443
1h1q2A6Cyclin-dependent kinase 22.7.11.220.443
3qqkX02Cyclin-dependent kinase 22.7.11.220.443
3r28XA0Cyclin-dependent kinase 22.7.11.220.443
3rpv26ZCyclin-dependent kinase 22.7.11.220.443
3plsANPMacrophage-stimulating protein receptor2.7.10.10.442
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.442
3s1h56ZCyclin-dependent kinase 22.7.11.220.440
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.440
4kd11QKCyclin-dependent kinase 22.7.11.220.440