sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 | 1.000 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.628 | |
| 1ef3 | FID | Aldose reductase | 1.1.1.21 | 0.618 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.612 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.610 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.604 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.604 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.603 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.603 | |
| 3s3g | TLT | Aldose reductase | 1.1.1.21 | 0.591 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.587 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.578 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.577 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.575 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.570 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.553 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.552 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.552 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.549 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.545 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.543 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.540 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.536 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.534 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.530 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.522 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.511 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.510 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.506 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.502 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.501 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.492 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.489 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.488 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.487 | |
| 3h4g | FID | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.487 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.482 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.481 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.480 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.479 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.479 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.478 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.477 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.477 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.476 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.475 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.475 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.473 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.472 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.472 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.471 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.471 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.471 | |
| 3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.471 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.470 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.470 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.469 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.469 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.468 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.468 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.468 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.468 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.467 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.467 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.467 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.467 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.466 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.466 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.465 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.464 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.464 | |
| 4nv0 | MG7 | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.464 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.463 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.463 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.462 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 3nhl | YTR | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.462 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.461 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.460 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.460 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.459 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.459 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.459 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.458 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.458 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.458 | |
| 3r94 | FLR | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.457 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.457 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.457 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.457 | |
| 2ycy | P32 | Beta-1 adrenergic receptor | / | 0.457 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.457 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.456 | |
| 5doz | NDP | JamJ | / | 0.456 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.455 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.455 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.455 | |
| 3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.455 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.455 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.455 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.454 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.454 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.454 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.454 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 3gsi | THG | Dimethylglycine oxidase | 1.5.3.10 | 0.454 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.454 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.453 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.453 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.452 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.452 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.452 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.452 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.452 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.452 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.452 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.451 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.451 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.451 | |
| 3qwi | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.451 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.450 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.450 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.450 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.450 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.450 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.450 | |
| 2jgs | BTN | Avidin | / | 0.449 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.449 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.449 | |
| 4bs4 | A64 | Tankyrase-2 | 2.4.2.30 | 0.449 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.449 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.449 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.449 | |
| 4gbr | CAU | Beta-2 adrenergic receptor | / | 0.449 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.448 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.448 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.448 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.448 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.448 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.448 | |
| 3qwh | KMP | 17beta-hydroxysteroid dehydrogenase | / | 0.448 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.448 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.448 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4kxj | P34 | Nucleoprotein | / | 0.448 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.448 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.447 | |
| 2ycw | CAU | Beta-1 adrenergic receptor | / | 0.447 | |
| 3nhj | A2Z | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.447 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 4n1f | CZH | Obelin | / | 0.447 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.446 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.446 | |
| 4u15 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.446 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.445 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2hzq | STR | Apolipoprotein D | / | 0.445 | |
| 3owx | XRA | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.445 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.445 | |
| 4kmz | FOL | Folate receptor beta | / | 0.445 | |
| 4nqg | CZH | Mitrocomin | / | 0.445 | |
| 1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.444 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.444 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.444 | |
| 3nhr | RZW | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.444 | |
| 4l0t | 1V0 | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.444 | |
| 5a8e | XTK | Beta-1 adrenergic receptor | / | 0.444 | |
| 1pk9 | 2FA | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.443 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.443 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3zpq | XF5 | Beta-1 adrenergic receptor | / | 0.443 | |
| 4hlf | 15Z | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.443 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.442 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.442 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.442 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.442 | |
| 4hlh | 20D | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.442 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 2bzs | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.441 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.441 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.441 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 4l34 | 1VG | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1nbh | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.440 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.440 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.440 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.440 |