Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3zdu38RCyclin-dependent kinase-like 32.7.11.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3zdu38RCyclin-dependent kinase-like 32.7.11.221.000
2cchATPCyclin-dependent kinase 22.7.11.220.504
3qxpX64Cyclin-dependent kinase 22.7.11.220.497
5e8ySTUTGF-beta receptor type-22.7.11.300.494
1di8DTQCyclin-dependent kinase 22.7.11.220.492
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.489
3rkb12ZCyclin-dependent kinase 22.7.11.220.489
2wihP48Cyclin-dependent kinase 22.7.11.220.488
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.488
3rak03ZCyclin-dependent kinase 22.7.11.220.487
2uzbC75Cyclin-dependent kinase 22.7.11.220.485
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.485
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
3at4CCKCasein kinase II subunit alpha2.7.11.10.484
2wxvWXVCyclin-dependent kinase 22.7.11.220.480
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.480
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.479
3s1h56ZCyclin-dependent kinase 22.7.11.220.477
4acm7YGCyclin-dependent kinase 22.7.11.220.477
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.476
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.476
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.476
4bgg844Activin receptor type-12.7.11.300.476
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.473
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.473
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.472
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.472
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.471
2vu3LZECyclin-dependent kinase 22.7.11.220.470
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.468
4fx360KCyclin-dependent kinase 22.7.11.220.468
2i40BLZCyclin-dependent kinase 22.7.11.220.467
3oom507Activin receptor type-12.7.11.300.466
3i60E86Mitogen-activated protein kinase 12.7.11.240.465
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.465
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.464
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.464
4fkw62KCyclin-dependent kinase 22.7.11.220.463
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.462
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.462
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.462
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.461
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.461
1g5sI17Cyclin-dependent kinase 22.7.11.220.460
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.460
2vv9IM9Cyclin-dependent kinase 22.7.11.220.460
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.460
4eok4SPCyclin-dependent kinase 22.7.11.220.460
4erwSTUCyclin-dependent kinase 22.7.11.220.460
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.460
1gih1PUCyclin-dependent kinase 22.7.11.220.459
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.459
3qtxX43Cyclin-dependent kinase 22.7.11.220.459
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.458
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.458
4bgq38RCyclin-dependent kinase-like 52.7.11.220.458
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.458
2iw84SPCyclin-dependent kinase 22.7.11.220.457
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.457
2pvnP63Casein kinase II subunit alpha2.7.11.10.457
2wpa889Cyclin-dependent kinase 22.7.11.220.457
3dogNNNCyclin-dependent kinase 22.7.11.220.457
3ral04ZCyclin-dependent kinase 22.7.11.220.457
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.457
2vttLZDCyclin-dependent kinase 22.7.11.220.456
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.456
1zys199Serine/threonine-protein kinase Chk12.7.11.10.455
3pe2E1BCasein kinase II subunit alpha2.7.11.10.455
3r9dX6BCyclin-dependent kinase 22.7.11.220.455
4ivb1J5Tyrosine-protein kinase JAK1/0.455
1fvv107Cyclin-dependent kinase 22.7.11.220.454
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.454
3be9P04Casein kinase II subunit alpha2.7.11.10.454
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.454
3sw418KCyclin-dependent kinase 22.7.11.220.454
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.454
1pkdUCNCyclin-dependent kinase 22.7.11.220.453
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.453
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.453
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.453
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.453
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.453
4grb0XGCasein kinase II subunit alpha2.7.11.10.453
4jia1K3Tyrosine-protein kinase JAK2/0.453
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.452
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.451
3rk708ZCyclin-dependent kinase 22.7.11.220.451
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.451
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.450
3tnwF18Cyclin-dependent kinase 22.7.11.220.450
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.450
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.450
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.449
4fkv61KCyclin-dependent kinase 22.7.11.220.449
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.449
4fv6E57Mitogen-activated protein kinase 12.7.11.240.449
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.448
2fvdLIACyclin-dependent kinase 22.7.11.220.448
2w17I19Cyclin-dependent kinase 22.7.11.220.448
2x1nX1NCyclin-dependent kinase 22.7.11.220.448
3r9hZ67Cyclin-dependent kinase 22.7.11.220.448
3rmf20ZCyclin-dependent kinase 22.7.11.220.448
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.448
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.448
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.448
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.448
4ii5ADPCyclin-dependent kinase 22.7.11.220.448
4wsqKSAAP2-associated protein kinase 12.7.11.10.448
5cvhADPCasein kinase II subunit alpha2.7.11.10.448
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.447
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.447
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.447
3nieANPMitogen-activated protein kinase/0.447
3rk507ZCyclin-dependent kinase 22.7.11.220.447
4btjATPTau-tubulin kinase 12.7.11.10.447
4hge15VTyrosine-protein kinase JAK2/0.447
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.447
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.447
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
1h1r6CPCyclin-dependent kinase 22.7.11.220.446
2hog710Serine/threonine-protein kinase Chk12.7.11.10.446
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.446
4qnyANPMitogen activated protein kinase, putative/0.446
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.446
5cvfATPCasein kinase II subunit alpha2.7.11.10.446
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.445
3uli1N3Cyclin-dependent kinase 22.7.11.220.445
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.445
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.445
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.444
1oirHDYCyclin-dependent kinase 22.7.11.220.444
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.444
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.444
2pvlP55Casein kinase II subunit alpha2.7.11.10.444
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.444
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.444
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.444
3sw719KCyclin-dependent kinase 22.7.11.220.444
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.444
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.444
4jqeANPCasein kinase II subunit alpha2.7.11.10.444
1xo2FSECyclin-dependent kinase 62.7.11.220.443
3lq5SLQCyclin-dependent kinase 92.7.11.220.443
3rk909ZCyclin-dependent kinase 22.7.11.220.443
3rni21ZCyclin-dependent kinase 22.7.11.220.443
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.443
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.443
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.443
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.443
4j95ACPFibroblast growth factor receptor 2/0.443
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.442
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.442
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.442
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.442
2zjwREFCasein kinase II subunit alpha2.7.11.10.442
3gxlQIGTGF-beta receptor type-12.7.11.300.442
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
3pj8404Cyclin-dependent kinase 22.7.11.220.442
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.442
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.442
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.442
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.442
5av2KMPDeath-associated protein kinase 12.7.11.10.442
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.441
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.441
3hmm855TGF-beta receptor type-12.7.11.300.441
3lpbNVBTyrosine-protein kinase JAK2/0.441
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.441
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.441
4dymIYZActivin receptor type-12.7.11.300.441
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.441
5e92ANPTGF-beta receptor type-22.7.11.300.441
2wipP49Cyclin-dependent kinase 22.7.11.220.440
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.440
3begANPSRSF protein kinase 12.7.11.10.440