sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3of3 | DIH | Purine nucleoside phosphorylase DeoD-type 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3of3 | DIH | Purine nucleoside phosphorylase DeoD-type 1 | / | 1.000 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.665 | |
| 4ts9 | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.592 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.586 | |
| 1k9s | FM2 | Purine nucleoside phosphorylase DeoD-type | / | 0.569 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.567 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.547 | |
| 1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.541 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.541 | |
| 1pr6 | XYA | Purine nucleoside phosphorylase DeoD-type | / | 0.540 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.540 | |
| 1a69 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.537 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.537 | |
| 1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.529 | |
| 2i4t | UA2 | Purine nucleoside phosphorylase, putative | / | 0.528 | |
| 2isc | 223 | Purine nucleoside phosphorylase, putative | / | 0.524 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.521 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.521 | |
| 4ts3 | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.515 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.508 | |
| 1pk9 | 2FA | Purine nucleoside phosphorylase DeoD-type | / | 0.508 | |
| 3phc | IM5 | Purine nucleoside phosphorylase | / | 0.504 | |
| 3uaw | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.493 | |
| 4tti | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.493 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.492 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.487 | |
| 1pr5 | TBN | Purine nucleoside phosphorylase DeoD-type | / | 0.484 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.481 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.473 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.471 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.464 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.461 | |
| 4da0 | GNG | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.460 | |
| 1odi | ADN | Purine nucleoside phosphorylase | / | 0.459 | |
| 5doz | NDP | JamJ | / | 0.458 | |
| 3arv | SAU | Chitinase A | / | 0.451 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.451 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.451 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.447 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.444 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.441 | |
| 5dp2 | NAP | CurF | / | 0.441 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 |