sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2osc | MUH | Angiopoietin-1 receptor | 2.7.10.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2osc | MUH | Angiopoietin-1 receptor | 2.7.10.1 | 1.000 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.575 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.555 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.526 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.524 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.520 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.519 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.516 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.516 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.514 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.510 | |
| 4c8b | 0LI | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.510 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.509 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.509 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.506 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.505 | |
| 2ofv | 242 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.505 | |
| 4v01 | 0LI | Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b | / | 0.500 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.498 | |
| 4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.496 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.491 | |
| 3vo3 | 0KF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.489 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.486 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.483 | |
| 3dko | IHZ | Ephrin type-A receptor 7 | 2.7.10.1 | 0.482 | |
| 3vw8 | DF6 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.482 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.480 | |
| 1fgi | SU1 | Fibroblast growth factor receptor 1 | / | 0.480 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.478 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.476 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.476 | |
| 4af3 | VX6 | Aurora kinase B | 2.7.11.1 | 0.475 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.473 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.472 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.472 | |
| 4b8m | VX6 | Aurora kinase B-A | 2.7.11.1 | 0.472 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.472 | |
| 3hng | 8ST | Vascular endothelial growth factor receptor 1 | 2.7.10.1 | 0.471 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.471 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.470 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3qri | 919 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.468 | |
| 5doz | NDP | JamJ | / | 0.468 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.467 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.466 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.466 | |
| 2jj2 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.466 | |
| 2jj2 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.466 | |
| 3fkn | FKN | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.466 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 3b2w | 9NH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.465 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 4o4f | ATP | Kinase | / | 0.465 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.464 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.464 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.464 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.464 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.464 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.463 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.463 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.462 | |
| 4agw | NG7 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.462 | |
| 2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.460 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.460 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.460 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.459 | |
| 3h1j | SMA | Cytochrome b | / | 0.459 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.459 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.458 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.458 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.458 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.458 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.457 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.457 | |
| 3eta | 351 | Insulin receptor | 2.7.10.1 | 0.457 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.456 | |
| 1qxo | FMN | Chorismate synthase | / | 0.456 | |
| 2wqb | QQ1 | Angiopoietin-1 receptor | 2.7.10.1 | 0.456 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.456 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.456 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.456 | |
| 3lu8 | IQX | Serum albumin | / | 0.456 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.456 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.456 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.456 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.456 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.456 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.455 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.455 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.454 | |
| 2g44 | T3O | Estrogen receptor | / | 0.454 | |
| 2qjy | SMA | Cytochrome b | / | 0.454 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.454 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.453 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.453 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.453 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.452 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.452 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.452 | |
| 3up3 | XCA | aceDAF-12 | / | 0.452 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.452 | |
| 1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.451 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.451 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.451 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.451 | |
| 4d9f | DCS | D-cysteine desulfhydrase | / | 0.451 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.451 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.451 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1w83 | L11 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 2fmn | 4HF | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.450 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.450 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.450 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.450 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.450 | |
| 1ppj | SMA | Cytochrome b | / | 0.449 | |
| 3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 4bc6 | XZN | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.449 | |
| 4o4e | ATP | Kinase | / | 0.449 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.449 | |
| 2bxo | OPB | Serum albumin | / | 0.448 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.448 | |
| 3eel | 53T | Uncharacterized protein | / | 0.448 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3mcy | ZH1 | FimH | / | 0.448 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.448 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.447 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.447 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.447 | |
| 2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.447 | |
| 2qu6 | 857 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.447 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.447 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.447 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2xsz | ATP | RuvB-like 2 | 3.6.4.12 | 0.446 | |
| 3fl4 | FL4 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4ag8 | AXI | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.446 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.445 | |
| 3cin | NAD | Myo-inositol-1-phosphate synthase-related protein | / | 0.445 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.445 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.445 | |
| 1eio | GCH | Gastrotropin | / | 0.444 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.444 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.444 | |
| 4qrc | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.444 | |
| 4v26 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.444 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.443 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.443 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.443 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.443 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 4cry | ACO | PanD regulatory factor | / | 0.443 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.443 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.443 | |
| 4qbj | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.443 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.443 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.443 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.442 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3fml | FML | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.442 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 4ict | 1ED | Mycocyclosin synthase | 1.14.21.9 | 0.442 | |
| 4o7u | THF | Thymidylate synthase | / | 0.442 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.441 | |
| 1pp9 | SMA | Cytochrome b | / | 0.441 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.441 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.441 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.441 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
| 4v12 | POG | MaoC like domain protein | / | 0.441 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.440 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.440 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.440 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.440 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 3acy | 702 | Dehydrosqualene synthase | / | 0.440 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.440 | |
| 3qcj | NX4 | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.440 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.440 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.440 | |
| 4agc | AXI | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.440 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.440 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.440 |