sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 1.000 | |
| 3c74 | ANU | Uridine phosphorylase | 2.4.2.3 | 0.637 | |
| 2hwu | URI | Uridine phosphorylase | 2.4.2.3 | 0.627 | |
| 5c80 | URI | Uridine phosphorylase | / | 0.604 | |
| 1tgv | 5UD | Uridine phosphorylase | 2.4.2.3 | 0.601 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.584 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.576 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.559 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.551 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.548 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.547 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.530 | |
| 4ts9 | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.521 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.515 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.514 | |
| 4tti | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.514 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.507 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.505 | |
| 1odi | ADN | Purine nucleoside phosphorylase | / | 0.498 | |
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.495 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.492 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.491 | |
| 2isc | 223 | Purine nucleoside phosphorylase, putative | / | 0.482 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.480 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.477 | |
| 3jsz | UPG | Uncharacterized protein | / | 0.476 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.470 | |
| 2i4t | UA2 | Purine nucleoside phosphorylase, putative | / | 0.457 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.453 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.450 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 4ogk | THM | Uridine phosphorylase | 2.4.2.3 | 0.445 | |
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.443 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.441 | |
| 1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.440 | |
| 4lrl | TTP | HD domain protein | / | 0.440 |