sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4b67 | FAD | L-ornithine N(5)-monooxygenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4b67 | FAD | L-ornithine N(5)-monooxygenase | / | 1.287 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 1.049 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.971 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.957 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.956 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.932 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.898 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.880 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.871 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.815 | |
| 4tlx | FDA | KtzI | / | 0.809 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.759 | |
| 4tm4 | FDA | KtzI | / | 0.757 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.756 | |
| 4tm3 | FAD | KtzI | / | 0.755 | |
| 4tm1 | FDA | KtzI | / | 0.754 | |
| 4tlz | FAD | KtzI | / | 0.740 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.738 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.732 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.728 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.727 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.727 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.723 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.719 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.716 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.712 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.709 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.708 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.706 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.703 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.702 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.699 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.699 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.699 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.698 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.698 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.696 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.696 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.695 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.694 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.692 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.692 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.691 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.691 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.691 | |
| 4tm0 | FAD | KtzI | / | 0.690 | |
| 4d04 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.689 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.684 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.684 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.681 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.680 | |
| 1h2h | NAD | L-aspartate dehydrogenase | 1.4.1.21 | 0.680 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.680 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.679 | |
| 3h5n | ATP | MccB protein | / | 0.679 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.678 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.674 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.674 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.674 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.673 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.672 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.670 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.670 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.670 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.670 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.668 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.668 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.668 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.668 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.667 | |
| 4d79 | ATP | tRNA threonylcarbamoyladenosine dehydratase | 6.1 | 0.667 | |
| 4nte | FAD | DepH | / | 0.667 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.667 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.665 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.665 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.665 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.665 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.664 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.663 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.663 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.662 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.662 | |
| 4iv8 | SAM | Phosphoethanolamine N-methyltransferase,putative | / | 0.661 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.660 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.660 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.659 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.658 | |
| 2dki | FAD | 3-hydroxybenzoate 4-monooxygenase | 1.14.13.23 | 0.658 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.658 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.658 | |
| 1pl6 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.657 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.657 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.657 | |
| 4jn9 | FAD | DepH | / | 0.657 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.656 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.656 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.656 | |
| 4k5r | FAD | Oxygenase | / | 0.655 | |
| 2qa1 | FAD | PgaE | / | 0.654 | |
| 3qj4 | FAD | Renalase | / | 0.654 | |
| 4x4j | FAD | Putative oxygenase | / | 0.654 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.653 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.653 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.653 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.653 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.653 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.652 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.652 | |
| 4y9d | NAI | C alpha-dehydrogenase | / | 0.652 | |
| 4k7y | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.651 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.650 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.650 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.650 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.650 |