Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1yqd NAP Sinapyl alcohol dehydrogenase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1yqd NAPSinapyl alcohol dehydrogenase / 1.433
1yqx NAPSinapyl alcohol dehydrogenase / 1.133
4gkv NADAlcohol dehydrogenase, propanol-preferring 1.1.1.1 1.031
4oaq NDPR-specific carbonyl reductase / 1.019
1r37 NADNAD-dependent alcohol dehydrogenase 1.1.1.1 0.981
3two NDPMannitol dehydrogenase / 0.962
4nfh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.936
1hld NADAlcohol dehydrogenase E chain 1.1.1.1 0.935
5kjc NAJAlcohol dehydrogenase E chain 1.1.1.1 0.935
1u3v NADAlcohol dehydrogenase 1B 1.1.1.1 0.925
1h2b NAJNAD-dependent alcohol dehydrogenase / 0.923
1mgo NADAlcohol dehydrogenase E chain 1.1.1.1 0.923
5cdt NAJAlcohol dehydrogenase E chain 1.1.1.1 0.921
4dxh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.919
5kcz NAJAlcohol dehydrogenase E chain 1.1.1.1 0.919
5kj1 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.919
5cdg NAJAlcohol dehydrogenase E chain 1.1.1.1 0.918
5cds NAJAlcohol dehydrogenase E chain 1.1.1.1 0.918
5kj6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.918
2ohx NADAlcohol dehydrogenase E chain 1.1.1.1 0.915
4dwv NAJAlcohol dehydrogenase E chain 1.1.1.1 0.913
5kje NAJAlcohol dehydrogenase E chain 1.1.1.1 0.907
1ht0 NADAlcohol dehydrogenase 1C 1.1.1.1 0.906
1hf3 NADAlcohol dehydrogenase E chain 1.1.1.1 0.904
5kcp NAJAlcohol dehydrogenase E chain 1.1.1.1 0.903
3oq6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.902
5kjf NAJAlcohol dehydrogenase E chain 1.1.1.1 0.898
2oxi NADAlcohol dehydrogenase E chain 1.1.1.1 0.897
3jv7 NADSecondary alcohol dehydrogenase / 0.896
1hsz NADAlcohol dehydrogenase 1B 1.1.1.1 0.894
4w6z 8IDAlcohol dehydrogenase 1 1.1.1.1 0.891
1lde NADAlcohol dehydrogenase E chain 1.1.1.1 0.878
1axe NADAlcohol dehydrogenase E chain 1.1.1.1 0.873
3cos NADAlcohol dehydrogenase 4 1.1.1.1 0.870
4nfs NAJAlcohol dehydrogenase E chain 1.1.1.1 0.860
2eer NADNAD-dependent alcohol dehydrogenase 1.1.1.1 0.851
4ng5 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.845
1het NADAlcohol dehydrogenase E chain 1.1.1.1 0.844
3wle NAD(R)-specific carbonyl reductase / 0.842
2jhf NADAlcohol dehydrogenase E chain 1.1.1.1 0.822
4c4o NADSADH / 0.819
1hdz NADAlcohol dehydrogenase 1B 1.1.1.1 0.817
1heu NADAlcohol dehydrogenase E chain 1.1.1.1 0.815
2xaa NADSecondary alcohol dehydrogenase / 0.809
1h6c NDPGlucose--fructose oxidoreductase 1.1.99.28 0.801
1adb CNDAlcohol dehydrogenase E chain 1.1.1.1 0.799
4xd2 NAIAlcohol dehydrogenase E chain 1.1.1.1 0.794
5env NADAlcohol dehydrogenase 1 1.1.1.1 0.790
1axg NADAlcohol dehydrogenase E chain 1.1.1.1 0.789
1a71 NADAlcohol dehydrogenase E chain 1.1.1.1 0.785
1qor NDPQuinone oxidoreductase 1 / 0.773
3d4p NADL-lactate dehydrogenase 1 1.1.1.27 0.772
1o8c NDPProbable acrylyl-CoA reductase AcuI 1.3.1.84 0.770
1llu NADAlcohol dehydrogenase / 0.769
3h3j NADL-lactate dehydrogenase 1 1.1.1.27 0.767
5a06 NDPGlucose-fructose oxidoreductase / 0.760
1u7h NADPutative ornithine cyclodeaminase / 0.757
4dlb NADS-(hydroxymethyl)glutathione dehydrogenase / 0.755
6adh NADAlcohol dehydrogenase E chain 1.1.1.1 0.755
1agn NADAlcohol dehydrogenase class 4 mu/sigma chain 1.1.1.1 0.752
1x7d NADPutative ornithine cyclodeaminase / 0.750
4cpd NADAlcohol dehydrogenase / 0.750
5a03 NDPGlucose-fructose oxidoreductase / 0.749
4rvu NDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) / 0.746
5a02 NAPGlucose-fructose oxidoreductase / 0.746
1p0f NAPNADP-dependent alcohol dehydrogenase 1.1.1.2 0.743
1h6a NDPGlucose--fructose oxidoreductase 1.1.99.28 0.741
1ofg NDPGlucose--fructose oxidoreductase 1.1.99.28 0.736
1hyh NADL-2-hydroxyisocaproate dehydrogenase / 0.731
4rqu NADAlcohol dehydrogenase class-P / 0.731
1mp0 NADAlcohol dehydrogenase class-3 1.1.1.1 0.730
1h6d NDPGlucose--fructose oxidoreductase 1.1.99.28 0.726
3jyn NDPQuinone oxidoreductase / 0.726
1uxj NADMalate dehydrogenase / 0.722
2fn7 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.721
3nx4 NAPPutative oxidoreductase / 0.719
2x0i NAIMalate dehydrogenase / 0.718
5a1t NAIL-lactate dehydrogenase / 0.717
3wbf NAPMeso-diaminopimelate D-dehydrogenase / 0.716
1gv0 NADMalate dehydrogenase / 0.715
1q0q NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.1.1.267 0.713
4ywj NAD4-hydroxy-tetrahydrodipicolinate reductase / 0.711
1pzh NADLactate dehydrogenase / 0.709
2x0r NADMalate dehydrogenase / 0.707
1t2d NADL-lactate dehydrogenase 1.1.1.27 0.706
1teh NADAlcohol dehydrogenase class-3 1.1.1.1 0.706
4nd3 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.706
1yb5 NAPQuinone oxidoreductase 1.6.5.5 0.705
4mdh NADMalate dehydrogenase, cytoplasmic 1.1.1.37 0.704
4nd2 A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.704
1ma0 NADAlcohol dehydrogenase class-3 1.1.1.1 0.702
1o6z NADMalate dehydrogenase / 0.702
1yl7 NAI4-hydroxy-tetrahydrodipicolinate reductase / 0.702
1wwk NAD307aa long hypothetical phosphoglycerate dehydrogenase / 0.701
2ekl NADD-3-phosphoglycerate dehydrogenase / 0.701
2zb3 NDPProstaglandin reductase 2 1.3.1.48 0.701
4tvb NADHomospermidine synthase 2.5.1.44 0.701
1adc PADAlcohol dehydrogenase E chain 1.1.1.1 0.699
1lld NADL-lactate dehydrogenase 2 1.1.1.27 0.697
2o4c NADErythronate-4-phosphate dehydrogenase / 0.697
4plp NADHomospermidine synthase 2.5.1.44 0.697
2vna NAPProstaglandin reductase 2 1.3.1.48 0.696
4b7x NAPProbable oxidoreductase / 0.696
2y05 NAPProstaglandin reductase 1 / 0.692
4ejm NAPPutative zinc-binding dehydrogenase / 0.692
2vhv NAIAlanine dehydrogenase 1.4.1.1 0.691
2yjz NAPMetalloreductase STEAP4 1.16.1 0.691
3baz NAPHydroxyphenylpyruvate reductase 1.1.1.237 0.691
3pdu NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.689
1h6b NDPGlucose--fructose oxidoreductase 1.1.99.28 0.688
1rye NDPGlucose--fructose oxidoreductase 1.1.99.28 0.688
2dt5 NADRedox-sensing transcriptional repressor Rex / 0.687
3abi NADUncharacterized protein / 0.687
3wbb NAPMeso-diaminopimelate D-dehydrogenase / 0.687
4nd4 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.686
1zh8 NAPUncharacterized protein / 0.685
4dl9 NADS-(hydroxymethyl)glutathione dehydrogenase / 0.685
4hfm NAP2-alkenal reductase (NADP(+)-dependent) / 0.684
4k28 NADShikimate dehydrogenase family protein / 0.684
4y1b NAPAntE / 0.684
3hwr NDP2-dehydropantoate 2-reductase / 0.683
4xqc NADHomospermidine synthase 2.5.1.44 0.683
1sow NADL-lactate dehydrogenase 1.1.1.27 0.682
2nnl NAPDihydroflavonol 4-reductase 1.1.1.219 0.681
3wyc NAPMeso-diaminopimelate D-dehydrogenase 1.4.1.16 0.681
5ees NAP4-hydroxy-tetrahydrodipicolinate reductase / 0.681
2c0c NAPProstaglandin reductase 3 1 0.680
3w6u NAP6-phosphogluconate dehydrogenase, NAD-binding protein / 0.679
4nu5 NADPhosphonate dehydrogenase 1.20.1.1 0.679
2g76 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.678
5mdh NADMalate dehydrogenase, cytoplasmic 1.1.1.37 0.675
2dfd NADMalate dehydrogenase, mitochondrial 1.1.1.37 0.674
2cvz NDP3-hydroxyisobutyrate dehydrogenase / 0.671
2gsd NADFormate dehydrogenase / 0.671
2yy7 NADL-threonine dehydrogenase / 0.671
2vhz NAIAlanine dehydrogenase 1.4.1.1 0.669
1guf NDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial 1.3.1.10 0.668
2voj NADAlanine dehydrogenase 1.4.1.1 0.667
2vwh NAPGlucose 1-dehydrogenase / 0.667
3m6i NADL-arabinitol 4-dehydrogenase 1.1.1.12 0.667
2h63 NAPBiliverdin reductase A 1.3.1.24 0.666
3pef NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.666
4nu6 NADPhosphonate dehydrogenase 1.20.1.1 0.666
1yon A2R2-dehydropantoate 2-reductase 1.1.1.169 0.665
3cin NADMyo-inositol-1-phosphate synthase-related protein / 0.665
3wsw NADL-lactate dehydrogenase / 0.665
1ryd NDPGlucose--fructose oxidoreductase 1.1.99.28 0.664
5lc1 NADL-threonine 3-dehydrogenase / 0.664
1piw NAPNADP-dependent alcohol dehydrogenase 6 1.1.1.2 0.663
3mvq NDPGlutamate dehydrogenase 1, mitochondrial 1.4.1.3 0.663
1do8 NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.662
2q3e NAIUDP-glucose 6-dehydrogenase 1.1.1.22 0.662
4z0p NDPNAD-dependent dehydrogenase / 0.662
1ez4 NADL-lactate dehydrogenase 1.1.1.27 0.661
3uko NADAlcohol dehydrogenase class-3 / 0.661
3x2f NAIAdenosylhomocysteinase / 0.661
4j4b NAIUncharacterized protein / 0.661
5doz NDPJamJ / 0.661
2ldb NADL-lactate dehydrogenase 1.1.1.27 0.660
2p5y NADUDP-glucose 4-epimerase / 0.660
3anm NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.1.1.267 0.660
3oet NADErythronate-4-phosphate dehydrogenase / 0.660
1uxk NADMalate dehydrogenase / 0.659
1vi2 NADQuinate/shikimate dehydrogenase / 0.659
3qwb NDPProbable quinone oxidoreductase 1.6.5.5 0.658
1e3l NADAlcohol dehydrogenase 4 1.1.1.1 0.657
1yba NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.657
3w8f NAD3-hydroxybutyrate dehydrogenase / 0.657
4e5m NAPPhosphonate dehydrogenase 1.20.1.1 0.657
1b8u NADMalate dehydrogenase / 0.656
3qvs NADMyo-inositol-1-phosphate synthase (Ino1) / 0.656
1pzg A3DLactate dehydrogenase / 0.655
4e5k NADPhosphonate dehydrogenase 1.20.1.1 0.655
4i1i NADMalate dehydrogenase / 0.655
4xr9 NADCalS8 / 0.655
4xrg NADHomospermidine synthase 2.5.1.44 0.655
1ybm NAPUncharacterized protein At5g02240 / 0.654
2q1t NADPutative nucleotide sugar epimerase/ dehydratase / 0.654
4e5n NADPhosphonate dehydrogenase 1.20.1.1 0.654
3anl NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.1.1.267 0.653
4xgi NADGlutamate dehydrogenase / 0.653
1wp4 NDP3-hydroxyisobutyrate dehydrogenase / 0.652
2aky AP5Adenylate kinase / 0.652
2q1u NADPutative nucleotide sugar epimerase/ dehydratase / 0.652
1ie3 NADMalate dehydrogenase / 0.651
5dul NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase / 0.651
2a92 NAIL-lactate dehydrogenase / 0.650
2q1s NAIPutative nucleotide sugar epimerase/ dehydratase / 0.650
4gae NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic 1.1.1.267 0.650
4j43 NADUncharacterized protein / 0.650
4u7w NDPMxaA / 0.650