Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1yl7 NAI 4-hydroxy-tetrahydrodipicolinate reductase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1yl7 NAI4-hydroxy-tetrahydrodipicolinate reductase / 1.038
4ywj NAD4-hydroxy-tetrahydrodipicolinate reductase / 0.814
5ees NAP4-hydroxy-tetrahydrodipicolinate reductase / 0.798
5kcz NAJAlcohol dehydrogenase E chain 1.1.1.1 0.736
3oq6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.734
4dwv NAJAlcohol dehydrogenase E chain 1.1.1.1 0.734
5kje NAJAlcohol dehydrogenase E chain 1.1.1.1 0.734
4nfh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.733
1h2b NAJNAD-dependent alcohol dehydrogenase / 0.728
1o6z NADMalate dehydrogenase / 0.723
4gkv NADAlcohol dehydrogenase, propanol-preferring 1.1.1.1 0.721
2ohx NADAlcohol dehydrogenase E chain 1.1.1.1 0.720
5env NADAlcohol dehydrogenase 1 1.1.1.1 0.720
4xd2 NAIAlcohol dehydrogenase E chain 1.1.1.1 0.719
2oxi NADAlcohol dehydrogenase E chain 1.1.1.1 0.718
1c1d NAIPhenylalanine dehydrogenase / 0.707
1axe NADAlcohol dehydrogenase E chain 1.1.1.1 0.706
5cds NAJAlcohol dehydrogenase E chain 1.1.1.1 0.706
5kjf NAJAlcohol dehydrogenase E chain 1.1.1.1 0.704
5kjc NAJAlcohol dehydrogenase E chain 1.1.1.1 0.703
1yqd NAPSinapyl alcohol dehydrogenase / 0.702
2dt5 NADRedox-sensing transcriptional repressor Rex / 0.702
1agn NADAlcohol dehydrogenase class 4 mu/sigma chain 1.1.1.1 0.697
2x0i NAIMalate dehydrogenase / 0.694
1pj2 NAINAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.693
4dxh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.692
5cdg NAJAlcohol dehydrogenase E chain 1.1.1.1 0.692
5kj6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.692
5cdt NAJAlcohol dehydrogenase E chain 1.1.1.1 0.691
1adc PADAlcohol dehydrogenase E chain 1.1.1.1 0.688
1heu NADAlcohol dehydrogenase E chain 1.1.1.1 0.687
1ht0 NADAlcohol dehydrogenase 1C 1.1.1.1 0.684
2jhf NADAlcohol dehydrogenase E chain 1.1.1.1 0.682
4e5n NADPhosphonate dehydrogenase 1.20.1.1 0.682
4gl4 NAIAlcohol dehydrogenase class-3 / 0.679
2fze APRAlcohol dehydrogenase class-3 1.1.1.1 0.678
5kj1 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.678
1lde NADAlcohol dehydrogenase E chain 1.1.1.1 0.677
4ng5 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.677
1efk NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.675
1het NADAlcohol dehydrogenase E chain 1.1.1.1 0.674
4xrg NADHomospermidine synthase 2.5.1.44 0.674
1llu NADAlcohol dehydrogenase / 0.673
1pj3 NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.672
3q2k NAIProbable oxidoreductase / 0.672
4nfs NAJAlcohol dehydrogenase E chain 1.1.1.1 0.672
1yqx NAPSinapyl alcohol dehydrogenase / 0.671
2ixa NADAlpha-N-acetylgalactosaminidase 3.2.1.49 0.669
2o4c NADErythronate-4-phosphate dehydrogenase / 0.669
3pdu NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.669
4bv9 NDPKetimine reductase mu-crystallin 1.5.1.25 0.669
1adb CNDAlcohol dehydrogenase E chain 1.1.1.1 0.668
1llq NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.668
2pv7 NADT-protein 1.3.1.12 0.668
1gq2 NAPNADP-dependent malic enzyme 1.1.1.40 0.667
1yba NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.666
4k28 NADShikimate dehydrogenase family protein / 0.666
1do8 NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.665
3n7u NADFormate dehydrogenase, chloroplastic/mitochondrial / 0.665
1u3v NADAlcohol dehydrogenase 1B 1.1.1.1 0.664
1u7h NADPutative ornithine cyclodeaminase / 0.664
3nt4 NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.664
3x2f NAIAdenosylhomocysteinase / 0.664
4okn NAIL-lactate dehydrogenase A chain 1.1.1.27 0.664
3jv7 NADSecondary alcohol dehydrogenase / 0.662
1npt NADGlyceraldehyde-3-phosphate dehydrogenase / 0.661
3nt2 NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.661
2p9c NAID-3-phosphoglycerate dehydrogenase 1.1.1.95 0.660
1gad NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.659
3cin NADMyo-inositol-1-phosphate synthase-related protein / 0.658
1uxj NADMalate dehydrogenase / 0.657
2eer NADNAD-dependent alcohol dehydrogenase 1.1.1.1 0.657
2g76 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.657
2ixb NADAlpha-N-acetylgalactosaminidase 3.2.1.49 0.657
2x0r NADMalate dehydrogenase / 0.657
3d4p NADL-lactate dehydrogenase 1 1.1.1.27 0.655
2jcv NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase / 0.654
4j43 NADUncharacterized protein / 0.654
4j49 NADUncharacterized protein / 0.653
5a02 NAPGlucose-fructose oxidoreductase / 0.653
3cos NADAlcohol dehydrogenase 4 1.1.1.1 0.651
3pef NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.651