Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1dss NAD Glyceraldehyde-3-phosphate dehydrogenase 1.2.1.12

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1dss NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 1.064
5c7o NADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific 1.2.1.12 0.927
4o59 NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.908
1u8f NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.887
4k9d NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.887
3qv1 NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic 1.2.1.13 0.879
2g82 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.878
3v1y NADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic 1.2.1.12 0.875
3cif NADGlyceraldehyde-3-phosphate dehydrogenase / 0.873
1vsv NADGlyceraldehyde-3-phosphate dehydrogenase / 0.865
3ksd NADGlyceraldehyde-3-phosphate dehydrogenase 1 / 0.865
4dbv NDPGlyceraldehyde-3-phosphate dehydrogenase / 0.864
2dbv NDPGlyceraldehyde-3-phosphate dehydrogenase / 0.860
3cps NADGlyceraldehyde-3-phosphate dehydrogenase / 0.855
4lsm NADGlyceraldehyde-3-phosphate dehydrogenase / 0.855
3cmc NADGlyceraldehyde-3-phosphate dehydrogenase / 0.848
1rm3 NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic 1.2.1.13 0.847
1hdg NADGlyceraldehyde-3-phosphate dehydrogenase / 0.845
3zcx NADGlyceraldehyde-3-phosphate dehydrogenase / 0.842
2vyn NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.836
3hja NADGlyceraldehyde-3-phosphate dehydrogenase / 0.835
1szj NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.833
2ep7 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.828
3lvf NADGlyceraldehyde-3-phosphate dehydrogenase 1 / 0.826
4o63 NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.826
4p8r NADGlyceraldehyde-3-phosphate dehydrogenase / 0.825
2vyv NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.823
3zdf NADGlyceraldehyde-3-phosphate dehydrogenase / 0.813
4z0h NADGlyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic 1.2.1.12 0.809
3b1j NADGlyceraldehyde-3-phosphate dehydrogenase / 0.808
3dmt NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal 1.2.1.12 0.806
1gd1 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.803
3dbv NADGlyceraldehyde-3-phosphate dehydrogenase / 0.803
3k2b NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic 1.2.1.13 0.799
1f0y NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.798
3l4s NADGlyceraldehyde-3-phosphate dehydrogenase 1 / 0.797
1ywg NADGlyceraldehyde-3-phosphate dehydrogenase / 0.794
1dc6 NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.790
1a7k NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal 1.2.1.12 0.787
3had NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.784
1jn0 NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic 1.2.1.13 0.780
1nqo NADGlyceraldehyde-3-phosphate dehydrogenase / 0.778
1gad NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.776
1npt NADGlyceraldehyde-3-phosphate dehydrogenase / 0.774
3ids NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal 1.2.1.12 0.773
1m76 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.772
1il0 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.769
1nq5 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.766
3pym NADGlyceraldehyde-3-phosphate dehydrogenase 3 1.2.1.12 0.765
3doc NADGlyceraldehyde-3-phosphate dehydrogenase / 0.764
3f3s NADLambda-crystallin homolog / 0.764
1nqa NADGlyceraldehyde-3-phosphate dehydrogenase / 0.761
2d2i NAPGlyceraldehyde-3-phosphate dehydrogenase / 0.761
1rm4 NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic 1.2.1.13 0.756
1m75 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.754
1j0x NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.742
3adp NAILambda-crystallin 1.1.1.45 0.740
1znq NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.738
2b4r NADGlyceraldehyde-3-phosphate dehydrogenase / 0.735
1rm5 NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic 1.2.1.13 0.733
1gyp NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal 1.2.1.12 0.724
3hdh NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.722
1f17 NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.721
4wji NAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase / 0.719
2vhw NAIAlanine dehydrogenase 1.4.1.1 0.715
1cer NADGlyceraldehyde-3-phosphate dehydrogenase / 0.710
1nvm NADAcetaldehyde dehydrogenase 1.2.1.10 0.710
3ggp NADPrephenate dehydrogenase / 0.708
2q3e NAIUDP-glucose 6-dehydrogenase 1.1.1.22 0.707
1h2b NAJNAD-dependent alcohol dehydrogenase / 0.704
1sc6 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.704
1vc2 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.704
1uxj NADMalate dehydrogenase / 0.703
2g5c NADPrephenate dehydrogenase / 0.702
4boy NADGlyceraldehyde-3-phosphate dehydrogenase / 0.701
3hwr NDP2-dehydropantoate 2-reductase / 0.700
3keo NADRedox-sensing transcriptional repressor Rex / 0.700
1pjc NADAlanine dehydrogenase / 0.698
2hdh NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.698
3pqf NADL-lactate dehydrogenase 1.1.1.27 0.697
3wv8 ATPHmd co-occurring protein HcgE / 0.695
4okn NAIL-lactate dehydrogenase A chain 1.1.1.27 0.695
1jki NAIInositol-3-phosphate synthase 5.5.1.4 0.694
3ec7 NADInositol 2-dehydrogenase / 0.694
2hu2 NADC-terminal binding protein 1 / 0.692
1cf2 NAPGlyceraldehyde-3-phosphate dehydrogenase / 0.691
1lso NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.691
2pkr NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic 1.2.1.13 0.690
4k28 NADShikimate dehydrogenase family protein / 0.689
1u3v NADAlcohol dehydrogenase 1B 1.1.1.1 0.688
3oet NADErythronate-4-phosphate dehydrogenase / 0.688
1ml3 NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal 1.2.1.12 0.687
1qxs NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal 1.2.1.12 0.686
3nt2 NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.685
3wv7 ADPHmd co-occurring protein HcgE / 0.685
1hku NADC-terminal-binding protein 1 1.1.1 0.684
1uxk NADMalate dehydrogenase / 0.683
3pvz NADUDP-N-acetylglucosamine 4,6-dehydratase / 0.683
1c1d NAIPhenylalanine dehydrogenase / 0.682
1lld NADL-lactate dehydrogenase 2 1.1.1.27 0.681
4j43 NADUncharacterized protein / 0.681
1wwk NAD307aa long hypothetical phosphoglycerate dehydrogenase / 0.680
1la2 NADInositol-3-phosphate synthase 5.5.1.4 0.679
2f1k NAPPrephenate dehydrogenase / 0.679
2vhz NAIAlanine dehydrogenase 1.4.1.1 0.679
2nad NADFormate dehydrogenase / 0.678
3tri NAPPyrroline-5-carboxylate reductase / 0.677
1agn NADAlcohol dehydrogenase class 4 mu/sigma chain 1.1.1.1 0.676
2cvz NDP3-hydroxyisobutyrate dehydrogenase / 0.675
4dlb NADS-(hydroxymethyl)glutathione dehydrogenase / 0.675
5ein NAP[LysW]-L-2-aminoadipate 6-phosphate reductase / 0.673
5kjc NAJAlcohol dehydrogenase E chain 1.1.1.1 0.672
5kjf NAJAlcohol dehydrogenase E chain 1.1.1.1 0.672
1ur5 NADMalate dehydrogenase / 0.671
2ldb NADL-lactate dehydrogenase 1.1.1.27 0.671
1q0q NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.1.1.267 0.670
4gae NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic 1.1.1.267 0.668
3cin NADMyo-inositol-1-phosphate synthase-related protein / 0.667
1gae NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.666
1ht0 NADAlcohol dehydrogenase 1C 1.1.1.1 0.665
2q1w NADPutative nucleotide sugar epimerase/ dehydratase / 0.665
5ig2 NADShort-chain dehydrogenase/reductase SDR / 0.665
1hyh NADL-2-hydroxyisocaproate dehydrogenase / 0.664
2qg4 NADUDP-glucose 6-dehydrogenase 1.1.1.22 0.664
3wsw NADL-lactate dehydrogenase / 0.664
4ywj NAD4-hydroxy-tetrahydrodipicolinate reductase / 0.664
2vhx NADAlanine dehydrogenase 1.4.1.1 0.663
3oq6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.663
3b20 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.662
3jyo NADQuinate/shikimate dehydrogenase (NAD(+)) / 0.662
3ruc NADUDP-N-acetylglucosamine 4-epimerase / 0.662
4dpl NAPMalonyl-CoA reductase 1.2.1.75 0.662
1h2h NADL-aspartate dehydrogenase 1.4.1.21 0.661
3w6u NAP6-phosphogluconate dehydrogenase, NAD-binding protein / 0.661
2g76 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.660
2pa3 NAID-3-phosphoglycerate dehydrogenase 1.1.1.95 0.660
3o9z NADLipopolysaccaride biosynthesis protein wbpB / 0.660
2yy7 NADL-threonine dehydrogenase / 0.659
3x2f NAIAdenosylhomocysteinase / 0.659
1gl3 NDPAspartate-semialdehyde dehydrogenase / 0.658
2dfv NADL-threonine 3-dehydrogenase / 0.658
3nt2 NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.658
4lcj NADC-terminal-binding protein 2 / 0.658
1hsz NADAlcohol dehydrogenase 1B 1.1.1.1 0.657
1zmd NAIDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.657
3cos NADAlcohol dehydrogenase 4 1.1.1.1 0.656
3ntq NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.655
5js6 NAD17-beta-hydroxysteroid dehydrogenase 14 1.1.1 0.654
1yjq NAP2-dehydropantoate 2-reductase 1.1.1.169 0.653
3qvt NAIMyo-inositol-1-phosphate synthase (Ino1) / 0.653
1u1i NADMyo-inositol-1-phosphate synthase (Ino1) / 0.652
2o4c NADErythronate-4-phosphate dehydrogenase / 0.651
3a4v NADNDP-sugar epimerase / 0.651
3nt4 NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.651
4jji NADAlcohol dehydrogenase class-3 / 0.651
3uko NADAlcohol dehydrogenase class-3 / 0.650
4j49 NADUncharacterized protein / 0.650
4j49 NAIUncharacterized protein / 0.650