Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1byq ADP Heat shock protein HSP 90-alpha

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1byq ADPHeat shock protein HSP 90-alpha / 0.860
2xk2 ADPHeat shock protein HSP 90-alpha / 0.850
2yef ANPHeat shock protein HSP 90-alpha / 0.823
3t2s AGSHeat shock protein HSP 90-alpha / 0.821
3t1k ANPHeat shock protein HSP 90-alpha / 0.818
3t10 ACPHeat shock protein HSP 90-alpha / 0.813
4xcl AGSHeat shock cognate 90 kDa protein / 0.803
4xcj ADPHeat shock cognate 90 kDa protein / 0.802
3t0z ATPHeat shock protein HSP 90-alpha / 0.800
4gqt ADPHeat shock protein 90 / 0.793
4xc0 ACPHeat shock cognate 90 kDa protein / 0.780
2ior ADPChaperone protein HtpG / 0.751
4wud ANPDNA gyrase subunit B / 0.737
2e0a ANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.736
4gt8 ADPSensor protein VraS 2.7.13.3 0.733
5f5r ANPHeat shock protein 75 kDa, mitochondrial / 0.731
1yt0 ADPEndoplasmin / 0.729
4ivg ANPTNF receptor-associated protein 1 / 0.728
1gjv AGS[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 2.7.11.4 0.723
2o1u ANPEndoplasmin / 0.720
2wep ADPATP-dependent molecular chaperone HSP82 / 0.719
1z5c ADPType 2 DNA topoisomerase 6 subunit B / 0.712
1i59 ANPChemotaxis protein CheA 2.7.13.3 0.703
1y4s ADPChaperone protein HtpG / 0.699
1mx0 ANPType 2 DNA topoisomerase 6 subunit B / 0.695
4ipe ANPTNF receptor-associated protein 1 / 0.687
2xcm ADPCytosolic heat shock protein 90 / 0.686
3zkb ANPDNA gyrase subunit B / 0.686
3ehj ACPSensor histidine kinase DesK 2.7.13.3 0.683
1zxm ANPDNA topoisomerase 2-alpha 5.99.1.3 0.675
3ied AN2HSP90 / 0.674
1i58 ACPChemotaxis protein CheA 2.7.13.3 0.671
1i5b ANPChemotaxis protein CheA 2.7.13.3 0.671
2o1v ADPEndoplasmin / 0.670
4r3a ANPBlue-light-activated histidine kinase 2 2.7.13.3 0.670
3zkd ANPDNA gyrase subunit B / 0.669
1ea6 ADPMismatch repair endonuclease PMS2 3.1 0.668
1z59 ADPType 2 DNA topoisomerase 6 subunit B / 0.667
3d2r ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.662
2zkj ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.656
1amw ADPATP-dependent molecular chaperone HSP82 / 0.655
1pvg ANPDNA topoisomerase 2 5.99.1.3 0.650