scPDB - Distribution of Cavity Similarity values of 3sm0 entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3sm0	AEK	Queuine tRNA-ribosyltransferase	2.4.2.29

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
3sm0	AEK	Queuine tRNA-ribosyltransferase	2.4.2.29	1.000
4gh1	0WX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.831
3ge7	AFQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.708
4gh3	0EV	Queuine tRNA-ribosyltransferase	2.4.2.29	0.687
4gg9	0WW	Queuine tRNA-ribosyltransferase	2.4.2.29	0.663
1q63	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.660
4fps	0UX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.657
1y5v	NE8	Queuine tRNA-ribosyltransferase	2.4.2.29	0.629
4gi4	0EX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.626
2z1x	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.624
4gkt	0O1	Queuine tRNA-ribosyltransferase	2.4.2.29	0.610
1y5x	E89	Queuine tRNA-ribosyltransferase	2.4.2.29	0.602
1q65	BHB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.596
1q4w	DQU	Queuine tRNA-ribosyltransferase	2.4.2.29	0.586
1efz	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.583
4giy	0WY	Queuine tRNA-ribosyltransferase	2.4.2.29	0.575
4fr1	0V2	Queuine tRNA-ribosyltransferase	2.4.2.29	0.571
2z1w	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.563
1ozq	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.558
1f3e	DPZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.557
1q66	KMB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.552
4hvx	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.552
1y5w	NEZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.542
3gc5	2MQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.542
4hqv	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.542
4gcx	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.541
2bbf	344	Queuine tRNA-ribosyltransferase	2.4.2.29	0.539
2qzr	S79	Queuine tRNA-ribosyltransferase	2.4.2.29	0.539
3gc4	AAQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.536
1k4g	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.532
4hsh	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.532
2pot	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.510
1ve3	SAM	Uncharacterized protein	/	0.509
4h7z	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.509
1n2v	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.498
4fsa	0V3	Queuine tRNA-ribosyltransferase	2.4.2.29	0.495
1pxg	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.490
1k4h	APQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.488
4q8p	CKR	Queuine tRNA-ribosyltransferase	2.4.2.29	0.484
1r5y	DQU	Queuine tRNA-ribosyltransferase	2.4.2.29	0.472
2wo7	ASV	Isopenicillin N synthase	1.21.3.1	0.470
4gkh	0J9	Aminoglycoside 3'-phosphotransferase AphA1-IAB	/	0.467
1vbn	YSA	Tyrosine--tRNA ligase	6.1.1.1	0.465
3n87	N87	3-dehydroquinate dehydratase	4.2.1.10	0.464
1zdg	UPG	Glycogenin-1	2.4.1.186	0.462
2uzu	L20	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.461
1efy	BZC	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.460
1it7	GUN	tRNA-guanine(15) transglycosylase	2.4.2.48	0.460
2a4x	BLM	Mitomycin-binding protein	/	0.459
2xau	ADP	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43	3.6.4.13	0.458
3bll	BPQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.458
4fgc	PQ0	NADPH-dependent 7-cyano-7-deazaguanine reductase	1.7.1.13	0.458
2g28	TDK	Pyruvate dehydrogenase E1 component	1.2.4.1	0.454
3g5i	DNB	Pyrimidine-specific ribonucleoside hydrolase RihA	/	0.454
2ivp	ATP	tRNA N6-adenosine threonylcarbamoyltransferase	/	0.451
3anm	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	1.1.1.267	0.451
4fex	0TO	Aminoglycoside 3'-phosphotransferase AphA1-IAB	/	0.451
4u7w	NDP	MxaA	/	0.451
4ug5	H4B	Nitric oxide synthase oxygenase	1.14.13.165	0.451
2oci	TYC	Valacyclovir hydrolase	3.1	0.450
2zzc	NAP	Thioredoxin reductase 1, cytoplasmic	1.8.1.9	0.450
1gax	VAA	Valine--tRNA ligase	6.1.1.9	0.449
2vcm	M11	Isopenicillin N synthase	1.21.3.1	0.448
3ele	PLP	Aminotransferase	/	0.447
4dan	2FA	Purine nucleoside phosphorylase DeoD-type	2.4.2.1	0.447
2a0y	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.446
4h4x	FAD	Biphenyl dioxygenase ferredoxin reductase subunit	/	0.446
2oal	FAD	Flavin-dependent tryptophan halogenase RebH	1.14.19.9	0.445
3jyo	NAD	Quinate/shikimate dehydrogenase (NAD(+))	/	0.445
1x8b	824	Wee1-like protein kinase	2.7.10.2	0.444
3exh	TPP	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	1.2.4.1	0.444
3exh	TPP	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	1.2.4.1	0.444
3ts1	TYA	Tyrosine--tRNA ligase	6.1.1.1	0.444
3p9k	SAH	Caffeic acid O-methyltransferase	/	0.443
2z2w	770	Wee1-like protein kinase	2.7.10.2	0.442
4gt8	ADP	Sensor protein VraS	2.7.13.3	0.442
1w1r	ZEA	Cytokinin dehydrogenase 1	1.5.99.12	0.441
4at0	FAD	Possible succinate dehydrogenase	/	0.441
4gmg	NAP	Yersiniabactin biosynthetic protein YbtU	/	0.441
4z9r	NAD	Omega-3 polyunsaturated fatty acid synthase subunit PfaD	/	0.441
2in6	839	Wee1-like protein kinase	2.7.10.2	0.440
3fhx	PLP	Pyridoxal kinase	2.7.1.35	0.440
3s6a	ANP	Adenosine monophosphate-protein transferase NmFic	2.7.7.n1	0.440
4l17	DNQ	Glutamate receptor 2	/	0.440
4o4e	ATP	Kinase	/	0.440