Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3qzgX67Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3qzgX67Cyclin-dependent kinase 22.7.11.221.000
3r7yZ04Cyclin-dependent kinase 22.7.11.220.597
3rk708ZCyclin-dependent kinase 22.7.11.220.595
3r9dX6BCyclin-dependent kinase 22.7.11.220.575
2a0cCK9Cyclin-dependent kinase 22.7.11.220.570
1pxmCK5Cyclin-dependent kinase 22.7.11.220.560
3r8lZ30Cyclin-dependent kinase 22.7.11.220.560
1ke5LS1Cyclin-dependent kinase 22.7.11.220.558
3qtuX44Cyclin-dependent kinase 22.7.11.220.553
3lfnA27Cyclin-dependent kinase 22.7.11.220.551
3r83Z14Cyclin-dependent kinase 22.7.11.220.546
3r8vZ62Cyclin-dependent kinase 22.7.11.220.546
3qqkX02Cyclin-dependent kinase 22.7.11.220.543
3rk909ZCyclin-dependent kinase 22.7.11.220.540
1oitHDTCyclin-dependent kinase 22.7.11.220.539
2btrU73Cyclin-dependent kinase 22.7.11.220.538
3qwjX6ACyclin-dependent kinase 22.7.11.220.538
3rjc06ZCyclin-dependent kinase 22.7.11.220.536
2c6o4SPCyclin-dependent kinase 22.7.11.220.535
3s1h56ZCyclin-dependent kinase 22.7.11.220.535
3iggEFQCyclin-dependent kinase 22.7.11.220.533
3r71X86Cyclin-dependent kinase 22.7.11.220.531
3rk507ZCyclin-dependent kinase 22.7.11.220.529
1ykr628Cyclin-dependent kinase 22.7.11.220.524
3rpv26ZCyclin-dependent kinase 22.7.11.220.524
2btsU32Cyclin-dependent kinase 22.7.11.220.523
3rmf20ZCyclin-dependent kinase 22.7.11.220.523
3r73X87Cyclin-dependent kinase 22.7.11.220.521
2uznC96Cyclin-dependent kinase 22.7.11.220.520
2xmyCDKCyclin-dependent kinase 22.7.11.220.520
4fkq42KCyclin-dependent kinase 22.7.11.220.519
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.517
3qtxX43Cyclin-dependent kinase 22.7.11.220.515
3s0o50ZCyclin-dependent kinase 22.7.11.220.515
3rpo24ZCyclin-dependent kinase 22.7.11.220.512
4fki09KCyclin-dependent kinase 22.7.11.220.512
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.509
2a4lRRCCyclin-dependent kinase 22.7.11.220.508
4ek610KCyclin-dependent kinase 22.7.11.220.508
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.507
3wblPDYCyclin-dependent kinase 22.7.11.220.507
3qu0X40Cyclin-dependent kinase 22.7.11.220.506
4fkj11KCyclin-dependent kinase 22.7.11.220.505
4kd11QKCyclin-dependent kinase 22.7.11.220.505
3rahO1ZCyclin-dependent kinase 22.7.11.220.503
4acm7YGCyclin-dependent kinase 22.7.11.220.503
4fkt48KCyclin-dependent kinase 22.7.11.220.501
1pxlCK4Cyclin-dependent kinase 22.7.11.220.498
3s2pPMUCyclin-dependent kinase 22.7.11.220.497
1pxoCK7Cyclin-dependent kinase 22.7.11.220.496
1w8cN69Cyclin-dependent kinase 22.7.11.220.496
1g5sI17Cyclin-dependent kinase 22.7.11.220.494
1gii1PUCyclin-dependent kinase 22.7.11.220.494
3qxoX65Cyclin-dependent kinase 22.7.11.220.494
4fkpLS5Cyclin-dependent kinase 22.7.11.220.494
3rak03ZCyclin-dependent kinase 22.7.11.220.493
2r3jSCJCyclin-dependent kinase 22.7.11.220.491
3rm618ZCyclin-dependent kinase 22.7.11.220.491
3qqlX03Cyclin-dependent kinase 22.7.11.220.490
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.489
3rm719ZCyclin-dependent kinase 22.7.11.220.489
2vthLZ2Cyclin-dependent kinase 22.7.11.220.488
2w06FRVCyclin-dependent kinase 22.7.11.220.488
2exmZIPCyclin-dependent kinase 22.7.11.220.487
3qtrX36Cyclin-dependent kinase 22.7.11.220.487
2r3kSCQCyclin-dependent kinase 22.7.11.220.486
3rkb12ZCyclin-dependent kinase 22.7.11.220.484
3r1yX76Cyclin-dependent kinase 22.7.11.220.483
2b52D42Cyclin-dependent kinase 22.7.11.220.481
2w1hL0FCyclin-dependent kinase 22.7.11.220.481
3ral04ZCyclin-dependent kinase 22.7.11.220.480
3py0SU9Cyclin-dependent kinase 22.7.11.220.479
1w0xOLOCyclin-dependent kinase 22.7.11.220.478
4ek816KCyclin-dependent kinase 22.7.11.220.478
1b38ATPCyclin-dependent kinase 22.7.11.220.477
3ql8X01Cyclin-dependent kinase 22.7.11.220.477
3lfqA28Cyclin-dependent kinase 22.7.11.220.476
2c6kDT2Cyclin-dependent kinase 22.7.11.220.475
3ezvEZVCyclin-dependent kinase 22.7.11.220.475
3qqfX07Cyclin-dependent kinase 22.7.11.220.474
4fks46KCyclin-dependent kinase 22.7.11.220.474
2uzoC62Cyclin-dependent kinase 22.7.11.220.473
1y91CT9Cyclin-dependent kinase 22.7.11.220.472
3r6xX84Cyclin-dependent kinase 22.7.11.220.472
3raiX85Cyclin-dependent kinase 22.7.11.220.472
4fkg4CKCyclin-dependent kinase 22.7.11.220.472
1gih1PUCyclin-dependent kinase 22.7.11.220.471
1ke6LS2Cyclin-dependent kinase 22.7.11.220.471
1v1k3FPCyclin-dependent kinase 22.7.11.220.471
3r28XA0Cyclin-dependent kinase 22.7.11.220.471
4fkv61KCyclin-dependent kinase 22.7.11.220.469
1p2a5BNCyclin-dependent kinase 22.7.11.220.468
4fklCK2Cyclin-dependent kinase 22.7.11.220.468
3r7vZ02Cyclin-dependent kinase 22.7.11.220.467
2vv9IM9Cyclin-dependent kinase 22.7.11.220.466
4bgh3I6Cyclin-dependent kinase 22.7.11.220.466
4ez30S0Cyclin-dependent kinase 22.7.11.220.466
1ckpPVBCyclin-dependent kinase 22.7.11.220.465
1ke7LS3Cyclin-dependent kinase 22.7.11.220.465
1oirHDYCyclin-dependent kinase 22.7.11.220.465
3qqhX0ACyclin-dependent kinase 22.7.11.220.465
3qzhX69Cyclin-dependent kinase 22.7.11.220.465
3rni21ZCyclin-dependent kinase 22.7.11.220.465
2r3lSCWCyclin-dependent kinase 22.7.11.220.464
3pxyJWSCyclin-dependent kinase 22.7.11.220.463
3unk0BYCyclin-dependent kinase 22.7.11.220.463
2vtsLZCCyclin-dependent kinase 22.7.11.220.461
1ke9LS5Cyclin-dependent kinase 22.7.11.220.460
1hckATPCyclin-dependent kinase 22.7.11.220.459
3rpy27ZCyclin-dependent kinase 22.7.11.220.459
1e1xNW1Cyclin-dependent kinase 22.7.11.220.458
1h0w207Cyclin-dependent kinase 22.7.11.220.458
3sw719KCyclin-dependent kinase 22.7.11.220.458
1di8DTQCyclin-dependent kinase 22.7.11.220.457
3sqq99ZCyclin-dependent kinase 22.7.11.220.456
1h1s4SPCyclin-dependent kinase 22.7.11.220.455
3roy22ZCyclin-dependent kinase 22.7.11.220.455
3sw418KCyclin-dependent kinase 22.7.11.220.453
2r3p3SCCyclin-dependent kinase 22.7.11.220.452
2duv371Cyclin-dependent kinase 22.7.11.220.451
2r64740Cyclin-dependent kinase 22.7.11.220.450
3fz1B98Cyclin-dependent kinase 22.7.11.220.450
3qx2X63Cyclin-dependent kinase 22.7.11.220.450
3r8pZ46Cyclin-dependent kinase 22.7.11.220.449
3qtzX42Cyclin-dependent kinase 22.7.11.220.448
3my5RFZCyclin-dependent kinase 22.7.11.220.447
1pxpCK8Cyclin-dependent kinase 22.7.11.220.444
1vyzN5BCyclin-dependent kinase 22.7.11.220.444
3r9hZ67Cyclin-dependent kinase 22.7.11.220.443
4fkr45KCyclin-dependent kinase 22.7.11.220.443
1fvt106Cyclin-dependent kinase 22.7.11.220.442
3ti1B49Cyclin-dependent kinase 22.7.11.220.442
4lyn1YGCyclin-dependent kinase 22.7.11.220.442
2c6iDT1Cyclin-dependent kinase 22.7.11.220.441
2r3iSCFCyclin-dependent kinase 22.7.11.220.441
3qxpX64Cyclin-dependent kinase 22.7.11.220.441
3lfsA07Cyclin-dependent kinase 22.7.11.220.440
3r9nZ68Cyclin-dependent kinase 22.7.11.220.440