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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3qtrX36Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3qtrX36Cyclin-dependent kinase 22.7.11.221.000
3r9dX6BCyclin-dependent kinase 22.7.11.220.635
3rpv26ZCyclin-dependent kinase 22.7.11.220.603
3rak03ZCyclin-dependent kinase 22.7.11.220.581
3rjc06ZCyclin-dependent kinase 22.7.11.220.579
3iggEFQCyclin-dependent kinase 22.7.11.220.574
2r3kSCQCyclin-dependent kinase 22.7.11.220.572
3rk708ZCyclin-dependent kinase 22.7.11.220.563
3ral04ZCyclin-dependent kinase 22.7.11.220.552
2w1hL0FCyclin-dependent kinase 22.7.11.220.549
2b52D42Cyclin-dependent kinase 22.7.11.220.548
1g5sI17Cyclin-dependent kinase 22.7.11.220.547
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.542
3s1h56ZCyclin-dependent kinase 22.7.11.220.542
2vttLZDCyclin-dependent kinase 22.7.11.220.541
3qqhX0ACyclin-dependent kinase 22.7.11.220.541
3rm618ZCyclin-dependent kinase 22.7.11.220.541
4acm7YGCyclin-dependent kinase 22.7.11.220.538
3qzgX67Cyclin-dependent kinase 22.7.11.220.537
3rni21ZCyclin-dependent kinase 22.7.11.220.535
2xmyCDKCyclin-dependent kinase 22.7.11.220.528
3qtxX43Cyclin-dependent kinase 22.7.11.220.526
3rkb12ZCyclin-dependent kinase 22.7.11.220.525
2a0cCK9Cyclin-dependent kinase 22.7.11.220.524
3rmf20ZCyclin-dependent kinase 22.7.11.220.524
4fks46KCyclin-dependent kinase 22.7.11.220.524
1w0xOLOCyclin-dependent kinase 22.7.11.220.523
3lfnA27Cyclin-dependent kinase 22.7.11.220.523
3qqlX03Cyclin-dependent kinase 22.7.11.220.523
3r83Z14Cyclin-dependent kinase 22.7.11.220.522
3ig7EFPCyclin-dependent kinase 22.7.11.220.516
3rk909ZCyclin-dependent kinase 22.7.11.220.515
4bgh3I6Cyclin-dependent kinase 22.7.11.220.514
3qwjX6ACyclin-dependent kinase 22.7.11.220.512
1y91CT9Cyclin-dependent kinase 22.7.11.220.511
3qtuX44Cyclin-dependent kinase 22.7.11.220.510
1pxlCK4Cyclin-dependent kinase 22.7.11.220.508
2fvdLIACyclin-dependent kinase 22.7.11.220.508
3rahO1ZCyclin-dependent kinase 22.7.11.220.506
2vv9IM9Cyclin-dependent kinase 22.7.11.220.504
3r8vZ62Cyclin-dependent kinase 22.7.11.220.504
3r1yX76Cyclin-dependent kinase 22.7.11.220.503
3ezvEZVCyclin-dependent kinase 22.7.11.220.502
3r8lZ30Cyclin-dependent kinase 22.7.11.220.501
4fkj11KCyclin-dependent kinase 22.7.11.220.500
1ykr628Cyclin-dependent kinase 22.7.11.220.498
4ek816KCyclin-dependent kinase 22.7.11.220.498
2r3jSCJCyclin-dependent kinase 22.7.11.220.497
3qu0X40Cyclin-dependent kinase 22.7.11.220.497
1pxmCK5Cyclin-dependent kinase 22.7.11.220.496
1urwI1PCyclin-dependent kinase 22.7.11.220.496
2w17I19Cyclin-dependent kinase 22.7.11.220.495
3py0SU9Cyclin-dependent kinase 22.7.11.220.495
4fkv61KCyclin-dependent kinase 22.7.11.220.494
2c6o4SPCyclin-dependent kinase 22.7.11.220.493
4fkr45KCyclin-dependent kinase 22.7.11.220.492
4fkw62KCyclin-dependent kinase 22.7.11.220.491
1ke5LS1Cyclin-dependent kinase 22.7.11.220.490
3qruX19Cyclin-dependent kinase 22.7.11.220.490
3rpo24ZCyclin-dependent kinase 22.7.11.220.489
3sw418KCyclin-dependent kinase 22.7.11.220.489
1gih1PUCyclin-dependent kinase 22.7.11.220.488
2r3lSCWCyclin-dependent kinase 22.7.11.220.488
3fz1B98Cyclin-dependent kinase 22.7.11.220.487
3qqkX02Cyclin-dependent kinase 22.7.11.220.486
1oitHDTCyclin-dependent kinase 22.7.11.220.485
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.485
2vtsLZCCyclin-dependent kinase 22.7.11.220.484
3lfqA28Cyclin-dependent kinase 22.7.11.220.484
1p2a5BNCyclin-dependent kinase 22.7.11.220.483
2b55D31Cyclin-dependent kinase 22.7.11.220.483
4fko20KCyclin-dependent kinase 22.7.11.220.483
2vu3LZECyclin-dependent kinase 22.7.11.220.482
2w06FRVCyclin-dependent kinase 22.7.11.220.482
4fkpLS5Cyclin-dependent kinase 22.7.11.220.481
1pxoCK7Cyclin-dependent kinase 22.7.11.220.480
1v1k3FPCyclin-dependent kinase 22.7.11.220.480
2btrU73Cyclin-dependent kinase 22.7.11.220.480
3sqq99ZCyclin-dependent kinase 22.7.11.220.480
4ii5ADPCyclin-dependent kinase 22.7.11.220.479
3pj8404Cyclin-dependent kinase 22.7.11.220.478
3qtzX42Cyclin-dependent kinase 22.7.11.220.478
4fkt48KCyclin-dependent kinase 22.7.11.220.478
3qtwX3ACyclin-dependent kinase 22.7.11.220.477
1ckpPVBCyclin-dependent kinase 22.7.11.220.473
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.473
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.472
3pxyJWSCyclin-dependent kinase 22.7.11.220.471
3qxoX65Cyclin-dependent kinase 22.7.11.220.471
1gii1PUCyclin-dependent kinase 22.7.11.220.468
3lfsA07Cyclin-dependent kinase 22.7.11.220.467
4ek610KCyclin-dependent kinase 22.7.11.220.467
4fkq42KCyclin-dependent kinase 22.7.11.220.467
3wblPDYCyclin-dependent kinase 22.7.11.220.465
4eon1ROCyclin-dependent kinase 22.7.11.220.465
2c6iDT1Cyclin-dependent kinase 22.7.11.220.464
2w05FRTCyclin-dependent kinase 22.7.11.220.464
3rk507ZCyclin-dependent kinase 22.7.11.220.464
4fki09KCyclin-dependent kinase 22.7.11.220.464
4fx360KCyclin-dependent kinase 22.7.11.220.464
3rpy27ZCyclin-dependent kinase 22.7.11.220.463
2r3p3SCCyclin-dependent kinase 22.7.11.220.462
1h1pCMGCyclin-dependent kinase 22.7.11.220.460
2iw84SPCyclin-dependent kinase 22.7.11.220.460
3r7yZ04Cyclin-dependent kinase 22.7.11.220.460
3r9oZ71Cyclin-dependent kinase 22.7.11.220.460
3s0o50ZCyclin-dependent kinase 22.7.11.220.459
2btsU32Cyclin-dependent kinase 22.7.11.220.458
2uzoC62Cyclin-dependent kinase 22.7.11.220.457
4nj32KDCyclin-dependent kinase 22.7.11.220.457
1aq1STUCyclin-dependent kinase 22.7.11.220.455
1oiyN41Cyclin-dependent kinase 22.7.11.220.455
3r8pZ46Cyclin-dependent kinase 22.7.11.220.455
3r9hZ67Cyclin-dependent kinase 22.7.11.220.455
4fkg4CKCyclin-dependent kinase 22.7.11.220.455
1oirHDYCyclin-dependent kinase 22.7.11.220.454
2uznC96Cyclin-dependent kinase 22.7.11.220.454
2vtqLZACyclin-dependent kinase 22.7.11.220.454
3s2pPMUCyclin-dependent kinase 22.7.11.220.454
1ke8LS4Cyclin-dependent kinase 22.7.11.220.453
4kd11QKCyclin-dependent kinase 22.7.11.220.453
3r7uX96Cyclin-dependent kinase 22.7.11.220.452
1ke6LS2Cyclin-dependent kinase 22.7.11.220.451
3qtsX46Cyclin-dependent kinase 22.7.11.220.450
3rzb02ZCyclin-dependent kinase 22.7.11.220.450
1pkdUCNCyclin-dependent kinase 22.7.11.220.449
3r8zZ63Cyclin-dependent kinase 22.7.11.220.449
4i3zADPCyclin-dependent kinase 22.7.11.220.449
3qwkX62Cyclin-dependent kinase 22.7.11.220.448
3sw719KCyclin-dependent kinase 22.7.11.220.448
1fvv107Cyclin-dependent kinase 22.7.11.220.447
2i40BLZCyclin-dependent kinase 22.7.11.220.447
3ti1B49Cyclin-dependent kinase 22.7.11.220.447
3unk0BYCyclin-dependent kinase 22.7.11.220.447
1e9hINRCyclin-dependent kinase 22.7.11.220.446
1fvt106Cyclin-dependent kinase 22.7.11.220.446
1oi9N20Cyclin-dependent kinase 22.7.11.220.446
2a4lRRCCyclin-dependent kinase 22.7.11.220.446
2j9mPY8Cyclin-dependent kinase 22.7.11.220.446
1di8DTQCyclin-dependent kinase 22.7.11.220.445
1h1s4SPCyclin-dependent kinase 22.7.11.220.445
1ke7LS3Cyclin-dependent kinase 22.7.11.220.444
1w8cN69Cyclin-dependent kinase 22.7.11.220.444
2r3r6SCCyclin-dependent kinase 22.7.11.220.444
1qmzATPCyclin-dependent kinase 22.7.11.220.442
4btjATPTau-tubulin kinase 12.7.11.10.442
3zh8C58Protein kinase C iota type2.7.11.130.441
4ivb1J5Tyrosine-protein kinase JAK1/0.441
2duv371Cyclin-dependent kinase 22.7.11.220.440
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3rpr25ZCyclin-dependent kinase 22.7.11.220.440