sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2e8h | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2e8h | SAH | Diphthine synthase | / | 1.000 | |
| 2dek | SAH | Diphthine synthase | / | 0.856 | |
| 2p6l | SAH | Diphthine synthase | / | 0.824 | |
| 2owv | SAH | Diphthine synthase | / | 0.795 | |
| 2dsg | SAH | Diphthine synthase | / | 0.792 | |
| 2egl | SAH | Diphthine synthase | / | 0.786 | |
| 2e16 | SAH | Diphthine synthase | / | 0.765 | |
| 2e08 | SAH | Diphthine synthase | / | 0.762 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.745 | |
| 2eni | SAH | Diphthine synthase | / | 0.741 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.732 | |
| 2emu | SAH | Diphthine synthase | / | 0.730 | |
| 2eeq | SAH | Diphthine synthase | / | 0.729 | |
| 2p6i | SAH | Diphthine synthase | / | 0.725 | |
| 2owu | SAH | Diphthine synthase | / | 0.716 | |
| 2egb | SAH | Diphthine synthase | / | 0.714 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.713 | |
| 2emr | SAH | Diphthine synthase | / | 0.710 | |
| 2dxv | SAH | Diphthine synthase | / | 0.705 | |
| 2ejj | SAH | Diphthine synthase | / | 0.705 | |
| 2en5 | SAH | Diphthine synthase | / | 0.703 | |
| 2dxw | SAH | Diphthine synthase | / | 0.697 | |
| 2e15 | SAH | Diphthine synthase | / | 0.692 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.689 | |
| 2ejk | SAH | Diphthine synthase | / | 0.687 | |
| 1wng | SAH | Diphthine synthase | / | 0.685 | |
| 2ehl | SAH | Diphthine synthase | / | 0.682 | |
| 2hux | SAH | Diphthine synthase | / | 0.682 | |
| 1vce | SAH | Diphthine synthase | / | 0.679 | |
| 2e17 | SAH | Diphthine synthase | / | 0.676 | |
| 2egs | SAH | Diphthine synthase | / | 0.676 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.671 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.670 | |
| 2el0 | SAH | Diphthine synthase | / | 0.669 | |
| 2hut | SAH | Diphthine synthase | / | 0.667 | |
| 2e8q | SAH | Diphthine synthase | / | 0.666 | |
| 2z6r | SAH | Diphthine synthase | / | 0.665 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.663 | |
| 2pcm | SAH | Diphthine synthase | / | 0.662 | |
| 2e8s | SAH | Diphthine synthase | / | 0.660 | |
| 2pck | SAH | Diphthine synthase | / | 0.659 | |
| 2e07 | SAH | Diphthine synthase | / | 0.658 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.658 | |
| 2p6d | SAH | Diphthine synthase | / | 0.655 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.654 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.653 | |
| 2pci | SAH | Diphthine synthase | / | 0.653 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.651 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.647 | |
| 2p6k | SAH | Diphthine synthase | / | 0.644 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.636 | |
| 2dsi | SAH | Diphthine synthase | / | 0.635 | |
| 2p5c | SAH | Diphthine synthase | / | 0.633 | |
| 2dsh | SAH | Diphthine synthase | / | 0.631 | |
| 2owk | SAH | Diphthine synthase | / | 0.630 | |
| 2eka | SAH | Diphthine synthase | / | 0.629 | |
| 2eld | SAH | Diphthine synthase | / | 0.628 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.624 | |
| 2e7r | SAH | Diphthine synthase | / | 0.621 | |
| 2ele | SAH | Diphthine synthase | / | 0.620 | |
| 2pch | SAH | Diphthine synthase | / | 0.620 | |
| 2pcg | SAH | Diphthine synthase | / | 0.616 | |
| 2e4n | SAH | Diphthine synthase | / | 0.615 | |
| 2dxx | SAH | Diphthine synthase | / | 0.614 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.606 | |
| 2p5f | SAH | Diphthine synthase | / | 0.606 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.606 | |
| 2e8r | SAH | Diphthine synthase | / | 0.602 | |
| 2huq | SAH | Diphthine synthase | / | 0.600 | |
| 2p2x | SAH | Diphthine synthase | / | 0.598 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.586 | |
| 2el3 | SAH | Diphthine synthase | / | 0.586 | |
| 2owf | SAH | Diphthine synthase | / | 0.586 | |
| 2p9d | SAH | Diphthine synthase | / | 0.582 | |
| 2pca | SAH | Diphthine synthase | / | 0.582 | |
| 2huv | SAH | Diphthine synthase | / | 0.575 | |
| 2ejz | SAH | Diphthine synthase | / | 0.567 | |
| 2owg | SAH | Diphthine synthase | / | 0.541 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.493 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.493 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.484 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.483 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.483 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.480 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.478 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.477 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.470 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.470 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.470 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.470 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.470 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.469 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.469 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.469 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.468 | |
| 2y3s | TIR | TamL | / | 0.468 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.467 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.466 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.466 | |
| 4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.466 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.464 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.464 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.463 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.462 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.461 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.461 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.461 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.461 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.461 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.460 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.460 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.460 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.460 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.459 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.459 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.459 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.458 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.458 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.458 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.458 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.457 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.457 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.457 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.457 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.457 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.457 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.457 | |
| 1vp6 | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.456 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.456 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.456 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.454 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.454 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.453 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.453 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.453 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.453 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.453 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4kgn | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.452 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.452 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.451 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.451 | |
| 3a3g | DLZ | Lumazine protein | / | 0.451 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.451 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.451 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.450 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.450 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.450 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.450 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.450 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 4kb9 | G79 | Protease | / | 0.449 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.449 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.448 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.446 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.446 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.446 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.446 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.446 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.446 | |
| 4jl5 | ADP | Adenylate kinase | / | 0.446 | |
| 4qec | NAP | ElxO | / | 0.446 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.445 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.445 | |
| 3b2e | ADP | ATPase GET3 | / | 0.445 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.445 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.445 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.445 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.445 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.445 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4pgh | SAM | Caffeic acid O-methyltransferase | / | 0.445 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.444 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.444 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.444 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.444 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.444 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.444 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1zdw | FLV | Prenyltransferase | / | 0.443 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.443 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.443 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.443 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.443 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.443 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.442 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.442 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.442 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.442 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.442 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.442 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.442 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 5dp2 | NAP | CurF | / | 0.442 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.441 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.441 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.441 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.441 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.441 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.441 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.441 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.440 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.440 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.440 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.440 | |
| 4blr | UTP | NTPase P4 | / | 0.440 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.440 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.440 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 |