Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1qgyFADFerredoxin--NADP reductase1.18.1.2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1qgyFADFerredoxin--NADP reductase1.18.1.21.000
1h85FADFerredoxin--NADP reductase1.18.1.20.860
1qh0FADFerredoxin--NADP reductase1.18.1.20.821
1go2FADFerredoxin--NADP reductase1.18.1.20.806
1b2rFADFerredoxin--NADP reductase1.18.1.20.805
1e64FADFerredoxin--NADP reductase1.18.1.20.796
1bjkFADFerredoxin--NADP reductase1.18.1.20.728
4c43FADFerredoxin--NADP reductase1.18.1.20.668
3zbtFADFerredoxin--NADP reductase1.18.1.20.636
2b5oFADFerredoxin--NADP reductase1.18.1.20.625
1gjrFADFerredoxin--NADP reductase1.18.1.20.624
3w5uFADFerredoxin/0.624
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.621
4bprFADFerredoxin--NADP reductase1.18.1.20.619
1qgzFADFerredoxin--NADP reductase1.18.1.20.617
1e63FADFerredoxin--NADP reductase1.18.1.20.614
3zc3FADFerredoxin--NADP reductase1.18.1.20.611
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.606
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.605
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.603
1sm4FADFerredoxin--NADP reductase/0.601
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.597
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.590
3vo2FADFerredoxin--NADP reductase/0.590
1w87FADFerredoxin--NADP reductase1.18.1.20.586
1ewyFADFerredoxin--NADP reductase1.18.1.20.580
1queFADFerredoxin--NADP reductase1.18.1.20.578
2rc6FADFerredoxin--NADP reductase/0.565
3qfsFADNADPH--cytochrome P450 reductase/0.565
1e62FADFerredoxin--NADP reductase1.18.1.20.560
1w35FADFerredoxin--NADP reductase1.18.1.20.560
1ogiFADFerredoxin--NADP reductase1.18.1.20.559
1gaqFADFerredoxin/0.554
1gawFADFerredoxin/0.554
1amoFADNADPH--cytochrome P450 reductase/0.547
1ogjFADFerredoxin--NADP reductase1.18.1.20.546
1fndFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.544
1h42FADFerredoxin--NADP reductase1.18.1.20.543
1ja1FADNADPH--cytochrome P450 reductase/0.537
4yaoFADNADPH--cytochrome P450 reductase/0.529
1gr1FADFerredoxin--NADP reductase1.18.1.20.526
3fpkFADFerredoxin-NADP reductase/0.524
2ok8FADFerredoxin--NADP reductase, apicoplast/0.515
2rc5FADFerredoxin--NADP reductase/0.514
2xncFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.514
3qftFADNADPH--cytochrome P450 reductase/0.512
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.494
1j9zFADNADPH--cytochrome P450 reductase/0.488
1cqxFADFlavohemoprotein/0.487
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.484
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.480
5ah5LSSLeucine--tRNA ligase/0.480
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.478
1krhFADBenzoate 1,2-dioxygenase electron transfer component1.18.1.30.476
2bpoFADNADPH--cytochrome P450 reductase/0.473
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.470
4fk8FADFerredoxin--NADP reductase/0.469
1f20FADNitric oxide synthase, brain1.14.13.390.467
3qfcFADNADPH--cytochrome P450 reductase/0.466
2v1aFMNNPH1-1/0.465
3vt7VDXVitamin D3 receptor/0.464
2zevIPEGeranylgeranyl pyrophosphate synthase/0.463
2bgiFADNADPH:ferredoxin reductase/0.461
1a8pFADFerredoxin--NADP reductase/0.459
2gjlFMNNitronate monooxygenase1.13.12.160.459
3br3ETHTH-type transcriptional regulator QacR/0.459
1dx6GNTAcetylcholinesterase3.1.1.70.457
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.457
3fsjD7KBenzoylformate decarboxylase4.1.1.70.457
3jqrFADFerredoxin--NADP reductase, apicoplast/0.457
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.456
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.456
4mv1ADPBiotin carboxylase6.3.4.140.454
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.452
3e6eDCSAlanine racemase/0.452
3otwCOAPhosphopantetheine adenylyltransferase/0.452
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.452
1fdrFADFerredoxin--NADP reductase1.18.1.20.451
3q43D66M1 family aminopeptidase3.4.110.451
4bfxZVXPantothenate kinase2.7.1.330.450
1u2rSO1Elongation factor 2/0.449
1x1cSAHC-20 methyltransferase/0.449
3wqmB29Diterpene synthase3.1.7.80.449
5a4wQCTGlutathione S-transferase F22.5.1.180.449
2ejzSAHDiphthine synthase/0.447
2wp9CBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.447
2wp9CBESuccinate dehydrogenase cytochrome b556 subunit/0.447
4b4dFADFerredoxin-NADP reductase/0.447
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.447
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.446
2qdxFADFerredoxin--NADP+ reductase/0.446
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.445
1hzzNAPNAD(P) transhydrogenase subunit beta1.6.1.20.445
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.445
3q9bB3NAcetylpolyamine amidohydrolase/0.445
1ae8AZLProthrombin3.4.21.50.444
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.444
2vnkFADNADPH:ferredoxin reductase/0.444
4fse0VABeta-secretase 13.4.23.460.444
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.443
3p0fBAUUridine phosphorylase 22.4.2.30.443
3vf60H6Glucokinase2.7.1.20.443
4bfwZVWPantothenate kinase2.7.1.330.443
1g28FMNPHY3/0.442
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.442
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.442
4e32DWNMethyltransferase/0.442
1lnmDTXBilin-binding protein/0.441
2owfSAHDiphthine synthase/0.441
3fazNOSPurine nucleoside phosphorylase/0.441
4ead0NPThymidine phosphorylase2.4.2.40.441
4q0kGA3Phytohormone-binding protein/0.441
2e0nSAHPrecorrin-2 C20-methyltransferase/0.440
2gevCOKPantothenate kinase2.7.1.330.440
2pk3GDDGDP-6-deoxy-D-mannose reductase/0.440
2vnhFADNADPH:ferredoxin reductase/0.440
3fr5I4AFatty acid-binding protein, adipocyte/0.440
4b68FADL-ornithine N(5)-monooxygenase/0.440
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4rh10TTSpore photoproduct lyase/0.440