sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5c80 | URI | Uridine phosphorylase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5c80 | URI | Uridine phosphorylase | / | 1.000 | |
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.592 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.592 | |
| 2hwu | URI | Uridine phosphorylase | 2.4.2.3 | 0.588 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.583 | |
| 3c74 | ANU | Uridine phosphorylase | 2.4.2.3 | 0.578 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.565 | |
| 1tgv | 5UD | Uridine phosphorylase | 2.4.2.3 | 0.562 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.560 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.552 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.538 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.536 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.504 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.499 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.491 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.483 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.476 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.472 | |
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.462 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.460 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.457 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 2isc | 223 | Purine nucleoside phosphorylase, putative | / | 0.455 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.451 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4ogk | THM | Uridine phosphorylase | 2.4.2.3 | 0.447 | |
| 4ts9 | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.446 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.443 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.440 |