scPDB - Distribution of Binding site Similarity values of 4h7z entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4h7z	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4h7z	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	1.000
3blo	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.728
4hsh	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.709
1f3e	DPZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.645
3bld	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.629
4hqv	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.619
1efz	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.593
3bll	BPQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.582
1k4g	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.569
4gcx	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.566
1ozq	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.559
4gg9	0WW	Queuine tRNA-ribosyltransferase	2.4.2.29	0.544
4hvx	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.526
4fsa	0V3	Queuine tRNA-ribosyltransferase	2.4.2.29	0.516
1k4h	APQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.503
2z1w	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.500
2vcm	M11	Isopenicillin N synthase	1.21.3.1	0.499
1pxg	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.497
3ge7	AFQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.486
4a4o	664	Serine/threonine-protein kinase PLK1	2.7.11.21	0.482
1q4w	DQU	Queuine tRNA-ribosyltransferase	2.4.2.29	0.481
1blz	ACV	Isopenicillin N synthase	1.21.3.1	0.480
1n2v	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.473
2wo7	ASV	Isopenicillin N synthase	1.21.3.1	0.470
2a9y	26A	Adenosine kinase	2.7.1.20	0.469
1qiq	ACC	Isopenicillin N synthase	1.21.3.1	0.467
2jb4	A14	Isopenicillin N synthase	1.21.3.1	0.467
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.466
3zoi	M2W	Isopenicillin N synthase	1.21.3.1	0.466
4gh1	0WX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.466
1d3d	BZT	Prothrombin	3.4.21.5	0.464
1ygk	RRC	Pyridoxal kinase	2.7.1.35	0.464
2ejz	SAH	Diphthine synthase	/	0.464
2c94	TSF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.463
1ejb	INJ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.462
4twn	B96	Ephrin type-A receptor 3	2.7.10.1	0.460
1bk0	ACV	Isopenicillin N synthase	1.21.3.1	0.459
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.459
2y60	M8F	Isopenicillin N synthase	1.21.3.1	0.459
3biz	61E	Wee1-like protein kinase	2.7.10.2	0.456
1p33	MTX	Pteridine reductase 1	1.5.1.33	0.453
2ouy	CMP	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.453
3zky	WT4	Isopenicillin N synthase	1.21.3.1	0.453
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.452
1syn	F89	Thymidylate synthase	/	0.451
2bbf	344	Queuine tRNA-ribosyltransferase	2.4.2.29	0.451
2rlc	CHD	Choloylglycine hydrolase	3.5.1.24	0.451
3pdq	KC6	Lysine-specific demethylase 4A	1.14.11	0.451
3tfy	COA	N-alpha-acetyltransferase 50	2.3.1	0.451
1tf7	ATP	Circadian clock protein kinase KaiC	2.7.11.1	0.450
1u9i	ATP	Circadian clock protein kinase KaiC	2.7.11.1	0.450
2rab	NAD	Glutathione amide reductase	/	0.450
1hb1	OCV	Isopenicillin N synthase	1.21.3.1	0.449
1qjf	ACS	Isopenicillin N synthase	1.21.3.1	0.449
2h44	7CA	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.449
1uae	UD1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.448
3rsv	3RS	Beta-secretase 1	3.4.23.46	0.448
4a32	2CD	Glycylpeptide N-tetradecanoyltransferase	/	0.448
4bbh	YBN	Glycylpeptide N-tetradecanoyltransferase	/	0.448
1hb3	SCV	Isopenicillin N synthase	1.21.3.1	0.447
1x8b	824	Wee1-like protein kinase	2.7.10.2	0.447
2vbp	VB1	Isopenicillin N synthase	1.21.3.1	0.447
3n0y	APC	Adenylate cyclase 2	/	0.447
1fgi	SU1	Fibroblast growth factor receptor 1	/	0.446
1obn	ASV	Isopenicillin N synthase	1.21.3.1	0.446
3rvh	HQ2	Lysine-specific demethylase 4A	1.14.11	0.446
1oc1	ASV	Isopenicillin N synthase	1.21.3.1	0.445
2qzr	S79	Queuine tRNA-ribosyltransferase	2.4.2.29	0.445
3gnc	QQQ	Glutaryl-CoA dehydrogenase	/	0.445
3k0f	ATP	Circadian clock protein kinase KaiC	2.7.11.1	0.445
2yne	YNE	Glycylpeptide N-tetradecanoyltransferase	/	0.444
2zre	AGS	Protein RecA	/	0.444
3lfe	Z84	Mitogen-activated protein kinase 14	/	0.444
2iya	ZIO	Oleandomycin glycosyltransferase	/	0.443
2mok	FMN	Flavodoxin 1	/	0.443
3qpg	3QP	Aspartate aminotransferase	2.6.1.1	0.443
1cq7	PY5	Aspartate aminotransferase	2.6.1.1	0.442
2bf7	HBI	Pteridine reductase 1	1.5.1.33	0.442
1e5q	NDP	Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]	1.5.1.10	0.440
4gh3	0EV	Queuine tRNA-ribosyltransferase	2.4.2.29	0.440