sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3q23 | G2P | Virion DNA-directed RNA polymerase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3q23 | G2P | Virion DNA-directed RNA polymerase | / | 1.000 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.490 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.471 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.469 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.465 | |
| 1rej | B1L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.460 | |
| 1o23 | UPG | Beta-1,4-galactosyltransferase 1 | / | 0.455 | |
| 3dzl | 3OC | Phenazine biosynthesis protein A/B | / | 0.455 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 3arw | CTI | Chitinase A | / | 0.451 | |
| 4zo3 | C6L | Acylhomoserine lactonase | / | 0.450 | |
| 5c80 | URI | Uridine phosphorylase | / | 0.450 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.448 | |
| 3cw9 | 01A | 4-chlorobenzoyl CoA ligase | / | 0.448 | |
| 3fpb | ATP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
| 1svh | I08 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2fyc | GDU | Beta-1,4-galactosyltransferase 1 | 2.4.1 | 0.447 | |
| 4lez | 1SY | Cyclic GMP-AMP synthase | / | 0.447 | |
| 4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.447 | |
| 1t8x | PEP | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.446 | |
| 4m2a | UPG | UDP-glucose pyrophosphorylase | / | 0.446 | |
| 5dm3 | ADP | L-glutamine synthetase | / | 0.446 | |
| 1oqm | UD2 | Beta-1,4-galactosyltransferase 1 | / | 0.445 | |
| 3tyc | XHP | Dihydropteroate synthase | / | 0.445 | |
| 3fzm | 3GO | Heat shock cognate 71 kDa protein | / | 0.444 | |
| 4ihq | ADP | Conserved Archaeal protein | / | 0.444 | |
| 5aqz | SGV | Heat shock 70 kDa protein 1A | / | 0.444 | |
| 1l2o | ADP | Myosin heavy chain, striated muscle | / | 0.443 | |
| 2nmv | ADP | UvrABC system protein B | / | 0.443 | |
| 4bur | NAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.443 | |
| 4wbb | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 1cy1 | TMP | DNA topoisomerase 1 | / | 0.442 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.442 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.442 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.441 | |
| 4k97 | ATP | Cyclic GMP-AMP synthase | / | 0.441 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.440 |