scPDB - Distribution of Binding site Similarity values of 2zro entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2zro	ADP	Protein RecA

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2zro	ADP	Protein RecA	/	1.000
2zrf	DTP	Protein RecA	/	0.673
2zre	AGS	Protein RecA	/	0.608
2zrj	AGS	Protein RecA	/	0.593
1xp8	AGS	Protein RecA	/	0.580
2zr9	DTP	Protein RecA	/	0.540
1xmv	ADP	Protein RecA	/	0.496
2a1h	GBN	Branched-chain-amino-acid aminotransferase, mitochondrial	2.6.1.42	0.484
2ewm	NAD	(S)-1-Phenylethanol dehydrogenase	1.1.1.311	0.474
3jsw	JAR	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.471
4b13	X25	Glycylpeptide N-tetradecanoyltransferase	/	0.469
1bil	0IU	Renin	3.4.23.15	0.468
3kpb	SAM	Uncharacterized protein MJ0100	/	0.468
4g2j	0WF	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.468
3k3h	BYE	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.466
1kbo	340	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.463
4c7k	NAP	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.463
2g1o	2IG	Renin	3.4.23.15	0.462
3gqv	NAP	Enoyl reductase LovC	1	0.461
3hl0	NAD	Maleylacetate reductase	/	0.461
2g1r	3IG	Renin	3.4.23.15	0.460
3rsv	3RS	Beta-secretase 1	3.4.23.46	0.460
2iko	7IG	Renin	3.4.23.15	0.459
4a31	2CB	Glycylpeptide N-tetradecanoyltransferase	/	0.458
2i7p	ACO	Pantothenate kinase 3	2.7.1.33	0.457
4amb	DUD	Putative glycosyl transferase	/	0.457
2y0m	ACO	Histone acetyltransferase KAT8	/	0.456
3r95	ACO	MccE protein	/	0.456
4e90	7RG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.456
1me6	IVS	Plasmepsin-2	3.4.23.39	0.455
2bf4	FMN	NADPH--cytochrome P450 reductase	/	0.455
5d3q	GDP	Dynamin-1	3.6.5.5	0.455
3q43	D66	M1 family aminopeptidase	3.4.11	0.454
2a57	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.453
3cb2	GDP	Tubulin gamma-1 chain	/	0.453
2i4q	UA4	Renin	3.4.23.15	0.452
2iku	LIY	Renin	3.4.23.15	0.452
4nd2	A3D	Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase	/	0.452
2ylz	FAD	Phenylacetone monooxygenase	1.14.13.92	0.451
3ieu	GDP	GTPase Era	/	0.451
4nbt	NAD	3-oxoacyl-[acyl-carrier-protein] reductase	/	0.451
1ju2	FAD	(R)-mandelonitrile lyase 2	4.1.2.10	0.450
3dy8	5GP	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.450
4m49	22Y	L-lactate dehydrogenase A chain	1.1.1.27	0.450
1kvk	ATP	Mevalonate kinase	2.7.1.36	0.449
2giq	NN2	Genome polyprotein	2.7.7.48	0.449
3ogw	IMN	Lactoperoxidase	1.11.1.7	0.449
4k36	SAM	Anaerobic sulfatase-maturating enzyme	1.8.98	0.449
4kby	C2E	Stimulator of interferon genes protein	/	0.449
4b14	4XB	Glycylpeptide N-tetradecanoyltransferase	/	0.448
2hun	NAD	336aa long hypothetical dTDP-glucose 4,6-dehydratase	/	0.447
3d91	REM	Renin	3.4.23.15	0.446
3mpi	FAD	Glutaryl-CoA dehydrogenase	1.3.99.32	0.446
4ge9	0L0	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.446
1odc	A8B	Acetylcholinesterase	3.1.1.7	0.445
1teh	NAD	Alcohol dehydrogenase class-3	1.1.1.1	0.445
2g1n	1IG	Renin	3.4.23.15	0.445
2g1s	4IG	Renin	3.4.23.15	0.445
3wqm	B29	Diterpene synthase	3.1.7.8	0.445
4bft	ZVT	Pantothenate kinase	2.7.1.33	0.445
4is3	NAD	3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2	1.17.98.1	0.445
1kp2	ATP	Argininosuccinate synthase	6.3.4.5	0.444
1mja	COA	Histone acetyltransferase ESA1	/	0.444
2vig	FAD	Short-chain specific acyl-CoA dehydrogenase, mitochondrial	1.3.8.1	0.444
2vij	C44	Beta-secretase 1	3.4.23.46	0.444
2zsa	ADP	Pantothenate kinase	2.7.1.33	0.444
3vsw	R31	Renin	3.4.23.15	0.444
4jlm	1NN	Deoxycytidine kinase	2.7.1.74	0.444
2a59	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.443
2g1y	5IG	Renin	3.4.23.15	0.443
2ivi	ACW	Isopenicillin N synthase	1.21.3.1	0.443
3a1c	ACP	Probable copper-exporting P-type ATPase A	3.6.3.54	0.443
3zbr	NAP	2',3'-cyclic-nucleotide 3'-phosphodiesterase	3.1.4.37	0.443
4nd3	NAD	Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase	/	0.443
2g22	6IG	Renin	3.4.23.15	0.442
2xlr	FAD	Putative flavin-containing monooxygenase	/	0.442
3dyl	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.442
1pq9	44B	Oxysterols receptor LXR-beta	/	0.441
2giv	ACO	Histone acetyltransferase KAT8	/	0.441
2ojt	UBA	Glutamate receptor ionotropic, kainate 1	/	0.441
3aez	GDP	Pantothenate kinase	2.7.1.33	0.441
3hk1	B64	Fatty acid-binding protein, adipocyte	/	0.441
4rvg	TYD	D-mycarose 3-C-methyltransferase	/	0.441
1q12	ATP	Maltose/maltodextrin import ATP-binding protein MalK	/	0.440
2fs4	PZ1	Renin	3.4.23.15	0.440
3duy	AFJ	Beta-secretase 1	3.4.23.46	0.440
3k3e	PDB	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.440
3mpj	FAD	Glutaryl-CoA dehydrogenase	1.3.99.32	0.440
3phi	NDP	Shikimate dehydrogenase (NADP(+))	/	0.440
4a2z	VIQ	Glycylpeptide N-tetradecanoyltransferase	/	0.440
4nbw	NAD	Short-chain dehydrogenase/reductase SDR	/	0.440
4nd4	NAD	Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase	/	0.440
5a3b	APR	SIR2 family protein	/	0.440