Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.11.000
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.547
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.526
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.523
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.522
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.517
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.511
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.506
1zys199Serine/threonine-protein kinase Chk12.7.11.10.496
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.496
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.494
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.492
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.490
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.490
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.489
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.485
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.483
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.481
4jq8KJ8Epidermal growth factor receptor2.7.10.10.481
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.480
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.479
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.477
3gubGUBDeath-associated protein kinase 12.7.11.10.476
2bkzSBCCyclin-dependent kinase 22.7.11.220.475
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.475
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.475
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.475
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.473
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.473
4y95746Tyrosine-protein kinase/0.473
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.472
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.472
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.472
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.472
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.471
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.469
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.469
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.468
1wvxBD4Death-associated protein kinase 12.7.11.10.468
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.468
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.466
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.466
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.466
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.466
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.466
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.465
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.465
2j0lANPFocal adhesion kinase 12.7.10.20.465
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.465
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.465
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.465
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.465
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.464
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.463
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.463
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.463
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.462
4y93746Tyrosine-protein kinase/0.462
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.462
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.460
3zdu38RCyclin-dependent kinase-like 32.7.11.220.460
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.459
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.458
2ckeIQUDeath-associated protein kinase 2/0.458
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.458
4fob0USALK tyrosine kinase receptor2.7.10.10.458
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.457
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.457
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.457
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.457
4o0wADNAurora kinase A2.7.11.10.457
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.456
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.456
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.455
2hog710Serine/threonine-protein kinase Chk12.7.11.10.455
3a62STURibosomal protein S6 kinase beta-12.7.11.10.455
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.455
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.455
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.454
2itpAEEEpidermal growth factor receptor2.7.10.10.454
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.454
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
4bgg844Activin receptor type-12.7.11.300.454
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.454
4j99ACPFibroblast growth factor receptor 2/0.454
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.454
2ijmADPFocal adhesion kinase 12.7.10.20.453
3bhy7CPDeath-associated protein kinase 3/0.453
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.453
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.452
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.452
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.451
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.451
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.451
5av2KMPDeath-associated protein kinase 12.7.11.10.451
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.450
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.450
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.450
5auwQUEDeath-associated protein kinase 12.7.11.10.450
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.449
3w2sW2REpidermal growth factor receptor2.7.10.10.449
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.449
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.449
5av3KMPDeath-associated protein kinase 12.7.11.10.449
1ppm0P1Penicillopepsin-13.4.23.200.448
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.448
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.448
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.448
3mtfA3FActivin receptor type-12.7.11.300.448
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.448
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.448
4dymIYZActivin receptor type-12.7.11.300.448
2wihP48Cyclin-dependent kinase 22.7.11.220.447
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.447
3ztxZTXAurora kinase B-A2.7.11.10.447
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.447
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.447
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.446
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.446
2wxvWXVCyclin-dependent kinase 22.7.11.220.445
3bqr4RBDeath-associated protein kinase 3/0.445
3nynSGVG protein-coupled receptor kinase 62.7.11.160.445
3zh8C58Protein kinase C iota type2.7.11.130.445
4gu610NFocal adhesion kinase 12.7.10.20.445
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.444
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.444
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.443
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.443
3gu6ADPDeath-associated protein kinase 12.7.11.10.442
4brxKGWFocal adhesion kinase 12.7.10.20.442
1py5PY1TGF-beta receptor type-12.7.11.300.441
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.441
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.441
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.441
4jrvKJVEpidermal growth factor receptor2.7.10.10.441
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.440
2i40BLZCyclin-dependent kinase 22.7.11.220.440
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.440
2x1nX1NCyclin-dependent kinase 22.7.11.220.440
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.440
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.440