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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2w71L23Biotin carboxylase6.3.4.14

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2w71L23Biotin carboxylase6.3.4.141.000
2v58LZJBiotin carboxylase6.3.4.140.570
2v5aLZLBiotin carboxylase6.3.4.140.563
2w6nOA2Biotin carboxylase6.3.4.140.546
2vr1ATFBiotin carboxylase6.3.4.140.537
2v59LZKBiotin carboxylase6.3.4.140.534
4mv4ACPBiotin carboxylase6.3.4.140.519
2j9gANPBiotin carboxylase6.3.4.140.509
2w6pOA4Biotin carboxylase6.3.4.140.491
2w6oOA3Biotin carboxylase6.3.4.140.486
2w6qOA5Biotin carboxylase6.3.4.140.486
4mv8ACPBiotin carboxylase6.3.4.140.485
2w6zL21Biotin carboxylase6.3.4.140.479
1blzACVIsopenicillin N synthase1.21.3.10.467
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.462
3jziJZLBiotin carboxylase6.3.4.140.461
2vn0TDZCytochrome P450 2C8/0.458
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.457
4mv1ADPBiotin carboxylase6.3.4.140.457
3jzfJZKBiotin carboxylase6.3.4.140.453
5a3bAPRSIR2 family protein/0.453
1xddAAYIntegrin alpha-L/0.452
2w6mOA1Biotin carboxylase6.3.4.140.451
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.450
4g1z0VPVitamin D3 receptor A/0.449
1dv2ATPBiotin carboxylase6.3.4.140.448
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.448
1cjvFOKAdenylate cyclase type 2/0.447
1cjvFOKAdenylate cyclase type 5/0.447
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.447
2y6fM9FIsopenicillin N synthase1.21.3.10.446
4uymVOR14-alpha sterol demethylase Cyp51B/0.446
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.444
4o701QKBromodomain-containing protein 4/0.442
4a8v2ANMajor pollen allergen Bet v 1-J/0.440