scPDB - Distribution of Binding site Similarity values of 1pwy entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1pwy	AC2	Purine nucleoside phosphorylase	2.4.2.1

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1pwy	AC2	Purine nucleoside phosphorylase	2.4.2.1	1.000
1rfg	GMP	Purine nucleoside phosphorylase	2.4.2.1	0.659
1v3q	2DI	Purine nucleoside phosphorylase	2.4.2.1	0.614
2a0x	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.597
1yry	MSG	Purine nucleoside phosphorylase	2.4.2.1	0.569
1fxu	GU7	Purine nucleoside phosphorylase	2.4.2.1	0.528
1rct	NOS	Purine nucleoside phosphorylase	2.4.2.1	0.511
1v48	HA1	Purine nucleoside phosphorylase	2.4.2.1	0.511
2a0w	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.509
3ggs	2FD	Purine nucleoside phosphorylase	2.4.2.1	0.509
1a9p	9DI	Purine nucleoside phosphorylase	2.4.2.1	0.508
1v45	3DG	Purine nucleoside phosphorylase	2.4.2.1	0.508
1a9s	NOS	Purine nucleoside phosphorylase	2.4.2.1	0.500
1rt9	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.499
1lv8	9PP	Purine nucleoside phosphorylase	2.4.2.1	0.498
1lvu	9PP	Purine nucleoside phosphorylase	2.4.2.1	0.497
1rr6	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.497
2a0y	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.496
2on6	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.471
1rsz	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.470
2q1w	NAD	Putative nucleotide sugar epimerase/ dehydratase	/	0.469
1b8n	IMG	Purine nucleoside phosphorylase	2.4.2.1	0.464
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.460
2q1t	NAD	Putative nucleotide sugar epimerase/ dehydratase	/	0.460
2q7o	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.460
2geu	COK	Pantothenate kinase	2.7.1.33	0.459
3k8q	22A	Purine nucleoside phosphorylase	2.4.2.1	0.457
1v2h	GUN	Purine nucleoside phosphorylase	2.4.2.1	0.455
2d1y	NAD	Oxidoreductase, short-chain dehydrogenase/reductase family	/	0.455
3bgs	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.454
1odc	A8B	Acetylcholinesterase	3.1.1.7	0.453
1drf	FOL	Dihydrofolate reductase	1.5.1.3	0.452
1g6k	NAD	Glucose 1-dehydrogenase	1.1.1.47	0.452
1zgb	A1E	Acetylcholinesterase	3.1.1.7	0.452
2gs9	SAH	Uncharacterized protein	/	0.450
5doz	NDP	JamJ	/	0.450
2ges	COK	Pantothenate kinase	2.7.1.33	0.449
4ey6	GNT	Acetylcholinesterase	3.1.1.7	0.449
1nup	NMN	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3	/	0.447
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.447
2iyf	ERY	Oleandomycin glycosyltransferase	2.4.1	0.446
2pzj	NAD	Putative nucleotide sugar epimerase/ dehydratase	/	0.446
2whq	HI6	Acetylcholinesterase	3.1.1.7	0.445
3zei	AWH	O-acetylserine sulfhydrylase	/	0.445
4bfs	ZVS	Pantothenate kinase	2.7.1.33	0.445
4b4v	L34	Bifunctional protein FolD	/	0.444
1h60	STR	Pentaerythritol tetranitrate reductase	/	0.443
2lfo	GCH	Fatty acid-binding protein, liver	/	0.443
4tvj	09L	Poly [ADP-ribose] polymerase 2	2.4.2.30	0.443
1v5y	4HC	Major NAD(P)H-flavin oxidoreductase	1.6.99	0.442
1v5z	2HC	Major NAD(P)H-flavin oxidoreductase	1.6.99	0.442
2cek	N8T	Acetylcholinesterase	3.1.1.7	0.440
2wzw	FMN	Nitroreductase NfnB	/	0.440
3zky	WT4	Isopenicillin N synthase	1.21.3.1	0.440
4ara	C56	Acetylcholinesterase	3.1.1.7	0.440
4yfy	0FX	VioF	/	0.440
5jy1	NAD	Putative short-chain dehydrogenase/reductase	/	0.440