Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5a05 NDP Glucose-fructose oxidoreductase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
5a05 NDPGlucose-fructose oxidoreductase / 1.400
5a03 NDPGlucose-fructose oxidoreductase / 1.393
5a04 NDPGlucose-fructose oxidoreductase / 1.360
5a02 NAPGlucose-fructose oxidoreductase / 1.319
5a06 NDPGlucose-fructose oxidoreductase / 1.302
1h6c NDPGlucose--fructose oxidoreductase 1.1.99.28 1.199
1ryd NDPGlucose--fructose oxidoreductase 1.1.99.28 1.123
1h6d NDPGlucose--fructose oxidoreductase 1.1.99.28 1.075
1h6a NDPGlucose--fructose oxidoreductase 1.1.99.28 1.058
1h6b NDPGlucose--fructose oxidoreductase 1.1.99.28 1.054
1evj NADGlucose--fructose oxidoreductase 1.1.99.28 1.016
1ofg NDPGlucose--fructose oxidoreductase 1.1.99.28 1.012
1zh8 NAPUncharacterized protein / 0.891
2glx NDP1,5-anhydro-D-fructose reductase / 0.821
2ixa NADAlpha-N-acetylgalactosaminidase 3.2.1.49 0.806
2ixb NADAlpha-N-acetylgalactosaminidase 3.2.1.49 0.799
3q2k NAIProbable oxidoreductase / 0.797
1rye NDPGlucose--fructose oxidoreductase 1.1.99.28 0.746
1nvm NADAcetaldehyde dehydrogenase 1.2.1.10 0.729
3oa2 NADUDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase / 0.712
3ec7 NADInositol 2-dehydrogenase / 0.710
1il0 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.701
1qr6 NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.701
1do8 NADNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.700
1m75 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.700
2dt5 NADRedox-sensing transcriptional repressor Rex / 0.698
2rcy NAPPyrroline-5-carboxylate reductase / 0.696
2yjz NAPMetalloreductase STEAP4 1.16.1 0.693
4pxz CLRP2Y purinoceptor 12 / 0.692
3o9z NADLipopolysaccaride biosynthesis protein wbpB / 0.690
3pdu NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.690
3wbf NAPMeso-diaminopimelate D-dehydrogenase / 0.690
1f0y NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.685
1pj2 NAINAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.683
4gmg NAPYersiniabactin biosynthetic protein YbtU / 0.683
2x6t NAPADP-L-glycero-D-manno-heptose-6-epimerase / 0.681
3h3j NADL-lactate dehydrogenase 1 1.1.1.27 0.681
3m2t NADProbable dehydrogenase / 0.681
3w6u NAP6-phosphogluconate dehydrogenase, NAD-binding protein / 0.680
3d4p NADL-lactate dehydrogenase 1 1.1.1.27 0.679
3two NDPMannitol dehydrogenase / 0.679
1kvr NADUDP-glucose 4-epimerase 5.1.3.2 0.678
2c29 NAPDihydroflavonol 4-reductase / 0.677
1nah NADUDP-glucose 4-epimerase 5.1.3.2 0.676
1p0f NAPNADP-dependent alcohol dehydrogenase 1.1.1.2 0.676
2vhw NAIAlanine dehydrogenase 1.4.1.1 0.676
3tri NAPPyrroline-5-carboxylate reductase / 0.676
1yjq NAP2-dehydropantoate 2-reductase 1.1.1.169 0.675
2q1t NADPutative nucleotide sugar epimerase/ dehydratase / 0.675
4xgi NADGlutamate dehydrogenase / 0.675
3cea NADMyo-inositol 2-dehydrogenase-like (Promiscuous) / 0.674
1lde NADAlcohol dehydrogenase E chain 1.1.1.1 0.673
4y0k NAPAntE / 0.673
3ruc NADUDP-N-acetylglucosamine 4-epimerase / 0.671
5bsf NADPyrroline-5-carboxylate reductase / 0.669
3bts NADGalactose/lactose metabolism regulatory protein GAL80 / 0.668
2w3b NDPDihydrofolate reductase 1.5.1.3 0.667
3h2s NDPPutative NADH-flavin reductase / 0.667
4c3s NADAldehyde Dehydrogenase / 0.665
2ahr NAPPyrroline-5-carboxylate reductase / 0.664
3wle NAD(R)-specific carbonyl reductase / 0.664
2f1k NAPPrephenate dehydrogenase / 0.663
3nt2 NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.663
3phi NDPShikimate dehydrogenase (NADP(+)) / 0.663
4py0 6ATP2Y purinoceptor 12 / 0.663
3mvq NDPGlutamate dehydrogenase 1, mitochondrial 1.4.1.3 0.662
3rua NADUDP-N-acetylglucosamine 4-epimerase / 0.662
3sxp NADADP-L-glycero-D-mannoheptose-6-epimerase / 0.662
1dr5 NAPDihydrofolate reductase 1.5.1.3 0.661
1xag NAD3-dehydroquinate synthase / 0.661
4fj2 NAP17beta-hydroxysteroid dehydrogenase / 0.661
4wji NAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase / 0.661
1dli UDXUDP-glucose 6-dehydrogenase / 0.660
1hyh NADL-2-hydroxyisocaproate dehydrogenase / 0.660
2q1w NADPutative nucleotide sugar epimerase/ dehydratase / 0.660
2qw8 NAPEugenol synthase 1 1.1.1.318 0.660
3b1j NADGlyceraldehyde-3-phosphate dehydrogenase / 0.660
2vq3 NAPMetalloreductase STEAP3 / 0.659
3zu2 NAIEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.658
1i3l NADUDP-glucose 4-epimerase / 0.657
1o8c NDPProbable acrylyl-CoA reductase AcuI 1.3.1.84 0.657
2gdz NAD15-hydroxyprostaglandin dehydrogenase [NAD(+)] 1.1.1.141 0.657
3sju NDPKeto reductase / 0.656
1hwz NDPGlutamate dehydrogenase 1, mitochondrial 1.4.1.3 0.655
1u8x NADMaltose-6'-phosphate glucosidase 3.2.1.122 0.655
1xg5 NAPDehydrogenase/reductase SDR family member 11 / 0.654
2i3g NAPN-acetyl-gamma-glutamyl-phosphate reductase 1.2.1.38 0.654
2nnl NAPDihydroflavonol 4-reductase 1.1.1.219 0.654
3had NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.654
1q0q NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.1.1.267 0.653
3l77 NJPShort-chain alcohol dehydrogenase / 0.652
3ru9 NADUDP-N-acetylglucosamine 4-epimerase / 0.651
4imp NDPPolyketide synthase extender modules 3-4 / 0.651
4z0p NDPNAD-dependent dehydrogenase / 0.651
1a71 NADAlcohol dehydrogenase E chain 1.1.1.1 0.650
1mv8 GDXGDP-mannose 6-dehydrogenase 1.1.1.132 0.650
1rkx NADCDP-D-glucose-4,6-dehydratase / 0.650
2yut NAPPutative short-chain oxidoreductase / 0.650
3tn7 NJPShort-chain alcohol dehydrogenase / 0.650
4bmv NAPShort-chain dehydrogenase / 0.650
4i3v NADAldehyde dehydrogenase (NAD+) / 0.650