Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2itv ANP Epidermal growth factor receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2itv ANPEpidermal growth factor receptor 2.7.10.1 0.836
3vjo ANPEpidermal growth factor receptor 2.7.10.1 0.773
3vjn ANPEpidermal growth factor receptor 2.7.10.1 0.719
2itx ANPEpidermal growth factor receptor 2.7.10.1 0.711
1j1c ADPGlycogen synthase kinase-3 beta 2.7.11.26 0.696
2gs7 ANPEpidermal growth factor receptor 2.7.10.1 0.693
1pyx ANPGlycogen synthase kinase-3 beta 2.7.11.26 0.691
1j1b ANPGlycogen synthase kinase-3 beta 2.7.11.26 0.690
1u5r ATPSerine/threonine-protein kinase TAO2 2.7.11.1 0.687
2acx ANPG protein-coupled receptor kinase 6 2.7.11.16 0.687
4iir ANPSerine/threonine-protein kinase PRP4 homolog 2.7.11.1 0.685
4rqk ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.684
4xx9 ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.684
1q97 ATPSerine/threonine-protein kinase SKY1 2.7.11.1 0.682
3lct ADPALK tyrosine kinase receptor 2.7.10.1 0.679
5dr2 ATPAurora kinase A 2.7.11.1 0.679
2eb3 ANPEpidermal growth factor receptor 2.7.10.1 0.678
3b2t M33Fibroblast growth factor receptor 2 / 0.678
4cki ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.677
4xlv ACPInsulin receptor 2.7.10.1 0.677
2eva ADNMitogen-activated protein kinase kinase kinase 7 2.7.11.25 0.675
1u54 ACPActivated CDC42 kinase 1 / 0.674
4btj ATPTau-tubulin kinase 1 2.7.11.1 0.674
3a7h ATPSerine/threonine-protein kinase 24 2.7.11.1 0.673
4bix ADPSensor histidine kinase CpxA / 0.673
1ig1 ANPDeath-associated protein kinase 1 2.7.11.1 0.672
4nm0 ADPGlycogen synthase kinase-3 beta 2.7.11.26 0.672
4xw5 ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.672
4o1p ANPRibonuclease L / 0.671
4uak ADPSerine/threonine-protein kinase MRCK beta 2.7.11.1 0.671
1jkk ANPDeath-associated protein kinase 1 2.7.11.1 0.669
2pvr ANPCasein kinase II subunit alpha 2.7.11.1 0.669
4xhg ADPUncharacterized protein / 0.669
5dt3 ATPAurora kinase A 2.7.11.1 0.669
2xrw ANPMitogen-activated protein kinase 8 2.7.11.24 0.668
4iak ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.667
4bn1 ADPAurora kinase A 2.7.11.1 0.666
4dee ADPAurora kinase A 2.7.11.1 0.666
4ekk ANPRAC-alpha serine/threonine-protein kinase 2.7.11.1 0.666
3t8o ATPRhodopsin kinase / 0.665
4fl1 ANPTyrosine-protein kinase SYK 2.7.10.2 0.665
4ieb ANPCalmodulin-domain protein kinase 1 / 0.665
4oa9 ANPProtein BRASSINOSTEROID INSENSITIVE 1 2.7.10.1 0.665
4otp ADPSerine/threonine-protein kinase RIO1 2.7.11.1 0.665
2qoq ANPEphrin type-A receptor 3 2.7.10.1 0.664
4gva ADPMitogen-activated protein kinase 1 2.7.11.24 0.664
1jnk ANPMitogen-activated protein kinase 10 2.7.11.24 0.663
4gt3 ATPMitogen-activated protein kinase 1 2.7.11.24 0.663
4oau ADP2-5A-dependent ribonuclease 3.1.26 0.663
1mru AGSSerine/threonine-protein kinase PknB 2.7.11.1 0.662
2c2a ADPSensor histidine kinase / 0.662
3niz ADPCdc2-like CDK2/CDC28 like protein kinase / 0.662
4aw1 ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.662
4ckj ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.662
4dt8 ADNAPH(2'')-Id / 0.662
1ol6 ATPAurora kinase A 2.7.11.1 0.661
3bu5 ATPInsulin receptor 2.7.10.1 0.661
1vhz APRADP compounds hydrolase NudE 3.6.1 0.660
3mfs ANPPeripheral plasma membrane protein CASK 2.7.11.1 0.660
3mia ANPCyclin-dependent kinase 9 2.7.11.22 0.660
4ifc ADPSerine/threonine-protein kinase PRP4 homolog 2.7.11.1 0.660
3blq ATPCyclin-dependent kinase 9 2.7.11.22 0.659
2ijm ATPFocal adhesion kinase 1 2.7.10.2 0.658
2opn SUFFarnesyl pyrophosphate synthase 2.5.1.10 0.658
4oac ADPProtein BRASSINOSTEROID INSENSITIVE 1 2.7.10.1 0.658
4mv3 ACPBiotin carboxylase 6.3.4.14 0.657
1ir3 ANPInsulin receptor 2.7.10.1 0.655
2pwl ACPFibroblast growth factor receptor 2 / 0.655
4fic 0ULProto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.655
4fl3 ANPTyrosine-protein kinase SYK 2.7.10.2 0.655
4riy ADPEpidermal growth factor receptor 2.7.10.1 0.655
1jpa ANPEphrin type-B receptor 2 2.7.10.1 0.654
2yaa ATPDeath-associated protein kinase 2 / 0.654
3c50 ADPRhodopsin kinase / 0.654
4iaz ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.654
5dn3 ATPAurora kinase A 2.7.11.1 0.654
3akl ANPSerine/threonine-protein kinase CtkA 2.7.11.1 0.653
3f5u ANPDeath-associated protein kinase 1 2.7.11.1 0.653
3o7l ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.653
4gvj ADPNon-receptor tyrosine-protein kinase TYK2 2.7.10.2 0.653
2olc ADPMethylthioribose kinase 2.7.1.100 0.652
2vwi ANPSerine/threonine-protein kinase OSR1 2.7.11.1 0.652
2ydk YDKSerine/threonine-protein kinase Chk1 2.7.11.1 0.652
3c4z ADPRhodopsin kinase / 0.652
3nsz ANPCasein kinase II subunit alpha 2.7.11.1 0.652
4f99 ADPCell division cycle 7-related protein kinase 2.7.11.1 0.652
4bfm ANPMaternal embryonic leucine zipper kinase 2.7.11.1 0.651
4iay ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.651
4q5h ANPProtein kinase OspG 2.7 0.651
3hrf ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.650
4gyi ADPUncharacterized protein / 0.650
5cvh ADPCasein kinase II subunit alpha 2.7.11.1 0.650