sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Farnesyl pyrophosphate synthase
ID:	FPPS_HUMAN
AC:	P14324
Organism:	Homo sapiens
Reign:	Eukaryota
TaxID:	9606
EC Number:	2.5.1.10

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Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

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Ligand binding site composition:

B-Factor:	44.040
Number of residues:	25
Including
Standard Amino Acids:	21
Non Standard Amino Acids:	3
Water Molecules:	1
Cofactors:
Metals:	MG MG MG

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Cavity properties

Ligandability	Volume (Å3)
0.830	1144.125

% Hydrophobic	% Polar
40.12	59.88
According to VolSite

HET Code:	SUF
Formula:	C4H10O7P2S
Molecular weight:	264.131 g/mol
DrugBank ID:	-
Buried Surface Area:	59.2 %
Polar Surface area:	170.43 Å2

Number of
H-Bond Acceptors:	7
H-Bond Donors:	2
Rings:	0
Aromatic rings:	0
Anionic atoms:	4
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	4

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Mass center Coordinates

X	Y	Z
15.2783	78.2668	25.6876

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