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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rpy27ZCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3rpy27ZCyclin-dependent kinase 22.7.11.221.000
3rmf20ZCyclin-dependent kinase 22.7.11.220.712
3ral04ZCyclin-dependent kinase 22.7.11.220.640
3s1h56ZCyclin-dependent kinase 22.7.11.220.588
3rak03ZCyclin-dependent kinase 22.7.11.220.565
3sw418KCyclin-dependent kinase 22.7.11.220.554
4bgh3I6Cyclin-dependent kinase 22.7.11.220.552
2w06FRVCyclin-dependent kinase 22.7.11.220.545
1p2a5BNCyclin-dependent kinase 22.7.11.220.542
4fkg4CKCyclin-dependent kinase 22.7.11.220.542
3r9dX6BCyclin-dependent kinase 22.7.11.220.541
3ezvEZVCyclin-dependent kinase 22.7.11.220.540
4fko20KCyclin-dependent kinase 22.7.11.220.535
2btsU32Cyclin-dependent kinase 22.7.11.220.531
1pxmCK5Cyclin-dependent kinase 22.7.11.220.530
3rk507ZCyclin-dependent kinase 22.7.11.220.527
1pxlCK4Cyclin-dependent kinase 22.7.11.220.525
4fkq42KCyclin-dependent kinase 22.7.11.220.518
4fkj11KCyclin-dependent kinase 22.7.11.220.516
1w0xOLOCyclin-dependent kinase 22.7.11.220.515
1urwI1PCyclin-dependent kinase 22.7.11.220.514
1ke5LS1Cyclin-dependent kinase 22.7.11.220.513
2vv9IM9Cyclin-dependent kinase 22.7.11.220.512
4ek610KCyclin-dependent kinase 22.7.11.220.512
3qzgX67Cyclin-dependent kinase 22.7.11.220.511
2xmyCDKCyclin-dependent kinase 22.7.11.220.510
1gii1PUCyclin-dependent kinase 22.7.11.220.509
3qtzX42Cyclin-dependent kinase 22.7.11.220.509
2c6iDT1Cyclin-dependent kinase 22.7.11.220.507
3qtxX43Cyclin-dependent kinase 22.7.11.220.507
1oitHDTCyclin-dependent kinase 22.7.11.220.506
3unk0BYCyclin-dependent kinase 22.7.11.220.505
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.503
1pxoCK7Cyclin-dependent kinase 22.7.11.220.502
2c6o4SPCyclin-dependent kinase 22.7.11.220.500
3rk708ZCyclin-dependent kinase 22.7.11.220.500
3py0SU9Cyclin-dependent kinase 22.7.11.220.499
4fkr45KCyclin-dependent kinase 22.7.11.220.496
3qtuX44Cyclin-dependent kinase 22.7.11.220.495
3qxoX65Cyclin-dependent kinase 22.7.11.220.494
4acm7YGCyclin-dependent kinase 22.7.11.220.494
3wblPDYCyclin-dependent kinase 22.7.11.220.493
1gih1PUCyclin-dependent kinase 22.7.11.220.492
3fz1B98Cyclin-dependent kinase 22.7.11.220.492
2w17I19Cyclin-dependent kinase 22.7.11.220.491
3qxpX64Cyclin-dependent kinase 22.7.11.220.490
2uzoC62Cyclin-dependent kinase 22.7.11.220.488
3r1sX73Cyclin-dependent kinase 22.7.11.220.487
4fkt48KCyclin-dependent kinase 22.7.11.220.487
1v1k3FPCyclin-dependent kinase 22.7.11.220.486
3r8lZ30Cyclin-dependent kinase 22.7.11.220.486
3uli1N3Cyclin-dependent kinase 22.7.11.220.485
1y91CT9Cyclin-dependent kinase 22.7.11.220.484
2vthLZ2Cyclin-dependent kinase 22.7.11.220.484
2w05FRTCyclin-dependent kinase 22.7.11.220.483
3sw719KCyclin-dependent kinase 22.7.11.220.483
2r64740Cyclin-dependent kinase 22.7.11.220.482
3qu0X40Cyclin-dependent kinase 22.7.11.220.482
1ke6LS2Cyclin-dependent kinase 22.7.11.220.481
2r3lSCWCyclin-dependent kinase 22.7.11.220.481
2a0cCK9Cyclin-dependent kinase 22.7.11.220.479
3rjc06ZCyclin-dependent kinase 22.7.11.220.479
4fkv61KCyclin-dependent kinase 22.7.11.220.479
2btrU73Cyclin-dependent kinase 22.7.11.220.478
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.478
3r7uX96Cyclin-dependent kinase 22.7.11.220.478
2uznC96Cyclin-dependent kinase 22.7.11.220.477
1ke9LS5Cyclin-dependent kinase 22.7.11.220.475
1ke8LS4Cyclin-dependent kinase 22.7.11.220.474
2r3p3SCCyclin-dependent kinase 22.7.11.220.474
3s2pPMUCyclin-dependent kinase 22.7.11.220.474
3rzb02ZCyclin-dependent kinase 22.7.11.220.473
3r9oZ71Cyclin-dependent kinase 22.7.11.220.472
1fvv107Cyclin-dependent kinase 22.7.11.220.471
1oiyN41Cyclin-dependent kinase 22.7.11.220.471
2w1hL0FCyclin-dependent kinase 22.7.11.220.471
1vyzN5BCyclin-dependent kinase 22.7.11.220.470
3r71X86Cyclin-dependent kinase 22.7.11.220.470
3rni21ZCyclin-dependent kinase 22.7.11.220.470
3rkb12ZCyclin-dependent kinase 22.7.11.220.469
4ez30S0Cyclin-dependent kinase 22.7.11.220.469
2j9mPY8Cyclin-dependent kinase 22.7.11.220.468
3qtrX36Cyclin-dependent kinase 22.7.11.220.468
3sqq99ZCyclin-dependent kinase 22.7.11.220.468
1ke7LS3Cyclin-dependent kinase 22.7.11.220.467
2vttLZDCyclin-dependent kinase 22.7.11.220.466
3qzhX69Cyclin-dependent kinase 22.7.11.220.466
3unj0BXCyclin-dependent kinase 22.7.11.220.466
4fki09KCyclin-dependent kinase 22.7.11.220.466
1pxpCK8Cyclin-dependent kinase 22.7.11.220.465
3rm719ZCyclin-dependent kinase 22.7.11.220.465
3s0o50ZCyclin-dependent kinase 22.7.11.220.465
2c6lDT4Cyclin-dependent kinase 22.7.11.220.464
3qqfX07Cyclin-dependent kinase 22.7.11.220.464
3lfnA27Cyclin-dependent kinase 22.7.11.220.463
4fkpLS5Cyclin-dependent kinase 22.7.11.220.463
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.462
3qqkX02Cyclin-dependent kinase 22.7.11.220.462
3r7vZ02Cyclin-dependent kinase 22.7.11.220.462
3rpv26ZCyclin-dependent kinase 22.7.11.220.462
1pxkCK3Cyclin-dependent kinase 22.7.11.220.460
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.458
4nj32KDCyclin-dependent kinase 22.7.11.220.458
3r1yX76Cyclin-dependent kinase 22.7.11.220.457
3raiX85Cyclin-dependent kinase 22.7.11.220.457
1y8yCT7Cyclin-dependent kinase 22.7.11.220.456
2r3iSCFCyclin-dependent kinase 22.7.11.220.456
1g5sI17Cyclin-dependent kinase 22.7.11.220.455
3iggEFQCyclin-dependent kinase 22.7.11.220.455
3qqhX0ACyclin-dependent kinase 22.7.11.220.455
3r83Z14Cyclin-dependent kinase 22.7.11.220.455
4fx360KCyclin-dependent kinase 22.7.11.220.455
1b38ATPCyclin-dependent kinase 22.7.11.220.454
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.454
3r73X87Cyclin-dependent kinase 22.7.11.220.454
3ti1B49Cyclin-dependent kinase 22.7.11.220.453
2bheBRYCyclin-dependent kinase 22.7.11.220.452
1oirHDYCyclin-dependent kinase 22.7.11.220.451
2iw84SPCyclin-dependent kinase 22.7.11.220.451
4ek816KCyclin-dependent kinase 22.7.11.220.450
1di8DTQCyclin-dependent kinase 22.7.11.220.449
2fvdLIACyclin-dependent kinase 22.7.11.220.448
3roy22ZCyclin-dependent kinase 22.7.11.220.448
1w8cN69Cyclin-dependent kinase 22.7.11.220.447
3r8zZ63Cyclin-dependent kinase 22.7.11.220.447
1ykr628Cyclin-dependent kinase 22.7.11.220.446
4fks46KCyclin-dependent kinase 22.7.11.220.446
2r3kSCQCyclin-dependent kinase 22.7.11.220.444
4fkw62KCyclin-dependent kinase 22.7.11.220.444
3nynSGVG protein-coupled receptor kinase 62.7.11.160.443
3ddpRC8Cyclin-dependent kinase 22.7.11.220.441
1oi9N20Cyclin-dependent kinase 22.7.11.220.440
2bhhRYUCyclin-dependent kinase 22.7.11.220.440
2wihP48Cyclin-dependent kinase 22.7.11.220.440